Pathology

Pathogenic Germline Variants Found in Breast Cancer Patients
There is still considerable debate on the value of multigene panel testing for inherited cancer in patients with breast cancer, based on both the prevalence of pathogenic/likely pathogenic (P/LP) variants and any therapeutic implications from genetic test results. More...18 Sep 2019

Gut Bacteria Linked to High Blood Pressure and Depression
The microbiome is the genetic material of all the microbes, bacteria, fungi, protozoa and viruses that live on and inside the human body. The number of genes in all the microbes in one person's microbiome is 200 times the number of genes in the human genome. More...17 Sep 2019

Vaping Illness Characterized by Lipid-Laden Cells in Lungs
Lung scans from patients with vaping illness look like a serious viral or bacterial pneumonia, but those tests come back negative. Instead, diagnosis has been based on exclusion of known causes of similar respiratory illnesses combined with knowing the patient has a history of vaping. More...17 Sep 2019

New Blood Test Helps Detect Brain Injury in Minutes
After traumatic brain injury (TBI), plasma concentration of glial fibrillary acidic protein (GFAP) correlates with intracranial injury visible on computerized axial tomography (CT) scan. Some patients with suspected TBI with normal CT findings show pathology on magnetic resonance imaging (MRI). More...11 Sep 2019


CTC Purification Enables Identification of Cancer-Linked Genetic Arrangements
The use of circulating tumor cells (CTCs) as a surrogate tumor source for molecular profiling of disease offers a potential noninvasive diagnostic solution for understanding underlying tumor biology, guiding treatment interventions, and monitoring disease progression. More...29 Aug 2019
In Other News
Proteinuria Contributes to Greater CKD Progression Risk in Men
Hormone Levels of Diabetic Men Not Related to Prostate Cancer Risk
Circulating Tumor Cells Directly Detected in Blood Samples
Combination of Gene Mutations Linked to Endometrial Cancer
Non-Invasive Imaging Detects Cancer at Molecular Level
Prognostic Value of Specific Biomarker in Prostate Cancer Authenticated
Pancreatic Cancer Risk Rises with Fasting Glucose
Electronic Device May Help Diagnose Early Bladder Cancer
Mutation Study Suggests Changes to Clinical Management
Molecular Test Accurately Distinguishes Breast Tumors
Urine Test Used to Individualize Bladder Cancer Treatment
Proteomics Approach Used for Analyses of Breast Cancer
Rare Inherited Enzyme Disorder Yields Insight into Fibrosis
Test Improves Accuracy in Identifying Precancerous Pancreatic Cysts
GWAS Links Novel Loci to Peripheral Artery Disease Risk
Immune Molecules Expressed Inside Mycetoma Lesions
Next-Generation Sequencing Identifies Monogenic Diabetes
Multigene Expression Profiling Assays Compared for Cancer
Low-Frequency TP53 Gene Mutations Also Found in Healthy Women
Blood Test Complements Colonoscopy for Lynch Syndrome Patients
Microbiome Composition Altered in Fibromyalgia Patients
Protein Linked to Aggressive Skin Cancer
Test Determines If Cancer Patients Require Chemotherapy
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.