Pathology
Neurofibromatosis Gene and Breast Cancer Resistance to Hormone Therapy
The cells of estrogen receptor positive (ER+) breast cancer have receptors that allow them to use the hormone estrogen to grow. Treatment with anti-estrogen hormone (endocrine) therapy can block the growth of the cancer cells. More...17 Mar 2020
Combined Biopsy Method Improves Prostate Cancer Diagnosis
Prostate cancer can vary widely in severity and its potential to spread. Low-grade prostate cancer is associated with a very low risk of cancer-specific death and often does not require treatment, whereas high-grade cancers are much more likely to spread and are responsible for most prostate cancer deaths. This makes the correct assessment of the cancer grade very important for treatment decisions. More...16 Mar 2020
Blood-Based MicroRNA Signatures Distinguishes Individuals with Lung Cancer
The overall low survival rate of patients with lung cancer calls for improved detection tools to enable better treatment options and improved patient outcomes. Lung cancer affects about 228,000 people a year in the USA and has a five-year survival rate just shy of 20%. More...16 Mar 2020
Blood Test Predicts Response to Immunotherapy in Metastatic NSCLC
Non-small cell lung cancer (NSCLC) patients with higher measures of tumor mutations that show up in a blood test generally have a better clinical response to PD-1-based immunotherapy treatments than patients with a lower measure of mutations. More...10 Mar 2020
Esophageal Cancer Precursor Detected by Electronic Nose Device
Barrett's esophagus is a condition in which the lining of the esophagus changes, becoming more like the lining of the small intestine rather than the esophagus. This occurs in the area where the esophagus is joined to the stomach. More...10 Mar 2020
Heterogeneous Populations of Melanoma Circulating Tumor Cells Detected
Circulating tumor cells (CTCs) can be assessed through a minimally invasive blood sample with potential utility as a predictive, prognostic and pharmacodynamic biomarker. The large heterogeneity of melanoma CTCs has hindered their detection and clinical application. More...02 Mar 2020
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In Other News
Severe Strongyloidiasis Infection Reported in Kidney Transplant Recipients
Proteogenomic Characterization of Endometrial Carcinoma Analyzed
All-Digital Histopathology Attained by Infrared-Optical Hybrid Microscopy
Several Genes Linked to Long QT Syndrome Reappraised
Lung Adenocarcinoma Genomic Features Differ in East Asians, Europeans
Blood Test Lead to Earlier Detection of Gastrointestinal Cancers
Lung Cancer Liquid Biopsy Guides MRD-Directed Adjuvant Therapy
Single-Cell Sequencing Identifies Breast Cancer Risk
Heart Transplant Monitoring Test Validated
Microbiota’s Role Explored in Colorectal Cancer Among the Young
Technique Predicts Cancer Recurrence Risk for Melanoma Patients
Imaging Mass Cytometry Uncovers Novel Breast Cancer Subgroups
Ovarian Cancer Protein Contributes to Alzheimer`s Disease Neurodegeneration
Homologous Recombination Defects Prevalent in African-American Cancer Patients
Genome-Wide Association Leads to Heart Failure Risk Loci
Helicobacter pylori Triggers Development of Stomach Disease
Prostate Cancer Diagnosed Better Using Artificial Intelligence
Diagnostic Biomarker Found for Esophageal Squamous Cell Carcinoma
21-Gene Recurrence Score Helps Radiation Decision-Making
Molecular Characteristics of Leptomeningeal Melanoma Metastases Identified
Patterns of Circulating MicroRNAs Characterize Lack of Sleep in Children and Adolescents
Tumor DNA Platform Classifies Colorectal Cancer
Plasma HSP90α Levels Used for Detection of Hepatocellular Carcinoma
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.