Pathology
African-American MS Patients Experience More Rapid B-Cell Repopulation
Multiple sclerosis (MS) is a potentially disabling disease of the brain and spinal cord (central nervous system). In MS, the immune system attacks the protective sheath (myelin) that covers nerve fibers and causes communication problems between the brain and the rest of the body. More...06 May 2021
GPS Assay Associated with Long-Term Prostate Cancer Outcomes
Long-term cancer outcomes are an important consideration when deciding between active surveillance (AS) and immediate treatment for newly diagnosed prostate cancer. Multiple prospective AS studies that predominantly include patients at the lowest risk of progression have demonstrated a low risk of distant metastasis (DM) and prostate cancer–specific mortality (PCSM) with extended follow-up. More...03 May 2021
New Genetic Factors Involved in Sudden Unexpected Death in Children
About 10% of deaths in infants and children occur suddenly and have no apparent cause. Sudden Unexpected Death in Pediatrics (SUDP) encompasses several related phenomena, including Sudden Infant Death Syndrome (SIDS), Sudden Unexplained Death in Childhood (SUDC), and Sudden Unexpected Infant Death (SUID). More...29 Apr 2021
Altered Perivascular Fibroblast Activity Precedes ALS Disease Onset
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease of the motor neurons that eventually causes muscular atrophy, paralysis and death. There is currently no cure. The cause of ALS is only understood in the 5% to 10% of patients who have an inherited form of the disease. More...28 Apr 2021
RNA-Sequencing Predicts Immunotherapy Success in Bladder Cancer
Urothelial carcinoma, also known as transitional cell carcinoma (TCC), is by far the most common type of bladder cancer. Urothelial cells also line other parts of the urinary tract, such as the part of the kidney that connects to the ureter (called the renal pelvis), the ureters, and the urethra. More...22 Apr 2021
Tissue Counterpart to Monoclonal B-Cell Lymphocytosis Characterized
Monoclonal B-cell lymphocytosis (MBL) was initially proposed to recognize patients with a monotypic B cell population identified by peripheral blood (PB) flow cytometry (FC) that did not meet numerical criteria for chronic lymphocytic leukemia (CLL). More...21 Apr 2021
Breast Cancer Histopathology Employs Infrared Spectroscopic Imaging
Digital analysis of cancer specimens using spectroscopic imaging coupled to machine learning is an emerging area that links spatially localized spectral signatures to tissue structure and disease. Breast histopathology, as an example of the broad relevance of these techniques, is critically important for clinical diagnoses. More...19 Apr 2021
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In Other News
Coagulation Dysfunction and Infection Evaluated in Patients with AECOPD
Spatial Landscape of Lung Pathology Investigated During COVID-19 Progression
Leukocyte Epigenomics and Artificial Intelligence Predict Late-Onset Alzheimer’s Disease
Single-Cell Transcriptomic Analysis Traces Neuroblastomas to Developing Adrenal Neuroblasts
Whole-Genome Sequencing Aids Rare Disease Diagnosis
Calcitonin and Procalcitonin Immunoassays Investigated for Medullary Thyroid Carcinoma
Immune Cells in Cerebrospinal Fluid Predict Response to Immunotherapy
Pediatric Pancreatic Cancer Diagnosed From cfDNA Fragments in Urine
CSF Biomarker Flags Parkinson's Pathology Much Earlier
Five Genes Help Predict Lewy Body Dementia
Clinical Germline Testing Evaluated for Pediatric Cancer Patients
Genetic Risk of Inflammatory Bowel Disease Appears Distinct in African Americans
ctDNA Provides Prognostic Clues in Advanced BRAF-Mutated Melanoma Cases
22-Gene Genomic Classifier Validated in Recurrent Prostate Cancer Patients
Blood Biomarker Predicts Dementia in Cerebral Small Vessel Disease
Proteogenomic And Metabolomic Studies Characterize Human Glioblastoma
Exome Sequencing Identified Pathogenic Variants in Cerebral Palsy Patients
Biomarkers Evaluate Kidney Injury in Cancer Patients
Biomarker Predicts Pancreatic Cancer Patients’ Response to CD40 Immunotherapy
TAP1 Gene Polymorphisms Associated with Recurrent Respiratory Papillomatosis
Blood Test Detects Early Colorectal Adenomas
Liquid Biopsy Predicts Colon Cancer Relapse Months Earlier
Cell-Free DNA Detects Heart Allograft Acute Rejection
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
