Pathology

Simple Urine Test Significantly Improves Detection of Adrenal Cancer
Prognosis for patients discovered to have an adrenal cortical carcinoma (ACC), a cancerous adrenal mass, is poor, and a cure is only achievable through early detection and surgery. The incidental discovery of an adrenal mass often triggers additional scans to determine whether the mass is cancerous. More...06 Aug 2020

Somatic Evolution Identified in Non-Neoplastic IBD-Affected Colon
Inflammatory bowel disease (IBD) is a debilitating disease characterized by repeated flares of intestinal inflammation. The two major subtypes of IBD, Crohn’s disease (CD) and ulcerative colitis (UC) are distinguished by the location, continuity, and nature of the inflammatory lesions. More...06 Aug 2020

Digital Pathology Solution Resolves the Tissue Floater Conundrum
In routine clinical practice, pathologists may encounter extraneous pieces of tissue on glass slides that could be because of contamination from other specimens. These are typically called tissue floaters. The dilemma pathologists often face is whether such a tissue floater truly belongs to the case in question, or if instead it represents a true contaminant from another patient’s sample in which case it should be ignored. More...30 Jul 2020

Pediatric Ependymoma Single-Cell Analysis Signatures Linked to Outcomes
An ependymoma is a tumor that arises from the ependyma, a tissue of the central nervous system. Usually, in pediatric cases the location is intracranial, while in adults it is spinal. The common location of intracranial ependymomas is the fourth ventricle. More...30 Jul 2020

Circulating Tumor DNA Associated with Triple-Negative Breast Cancer Recurrence
Patients with early-stage triple-negative breast cancer (TNBC) are frequently treated with neoadjuvant chemotherapy, based on the increased risk for recurrence and death associated with this category of tumors. More...27 Jul 2020

CtDNA Assay for Cancer Recurrence, MRD Applications Demonstrated
Circulating tumor DNA (ctDNA) is found in the bloodstream and refers to DNA that comes from cancerous cells and tumors. Most DNA is inside a cell's nucleus. As a tumor grows, cells die and are replaced by new ones. The dead cells get broken down and their contents, including DNA, are released into the bloodstream. More...22 Jul 2020

In Other News
Type 2 Diabetes Associated with Arrhythmic Daily Gut Microbe
Gene Genomic Prostate Score Test Evaluated as Prognosis Predictor
Early-Onset Preeclampsia Risk Reflected in Circulating Maternal Transcripts
Rapid Genomic Profiling of Colon Cancers Improves Therapy Selection
RNA Sequencing as Alternative to Immunohistochemistry in Cancer Diagnostics
Immune Cells Hampered Fighting Soft Tissue and Bone Sarcomas
Blood Test Could Predict Multiple Sclerosis Progression
Precision Medicine-Based Genetic Testing Developed for Prostate Cancer
Roche Advances Personalized Healthcare with Development of Image Analysis Algorithms Using Artificial Intelligence
Blood Test Predicts Prostate Cancer Treatment Response
Tumor Microbiome Appears to Vary with Cancer Type
Precision Oncology Confers Clinical Benefit in Relapsed Pediatric Cancer
Saliva-Based Assay Developed for HPV-Driven Oropharyngeal Cancer
Representative Tumor Sampling Method Lessens Molecular Analyses Bias
Germline Risk Variants Found in Prostate Cancer Patients
Non-Invasive Blood Assay Can Detect Early Colorectal Cancer
Microcytosis Is a Risk Marker of Cancer in Primary Care
Rare Kidney Cancer Marked by Molecular Features
Blood Test Shows Promise for Predicting Cancer
Bacterial Blood Infections Tied to Heightened Colon Cancer Risk
Multicancer Blood Test Aids Screen for Cancer Guide Intervention
Biomarker Data Improves Risk Prediction for Pancreatic Cancer
Targeted Next-Generation Sequencing Validated for Lysosomal Storage Disorders Diagnosis
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.