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Pathology

Image: Autoantibody order, timing helps predict genetically susceptible children most likely to get type 1 diabetes (Photo courtesy of the Morsani College of Medicine).

Autoantibody Timing Predicts Genetically At-Risk Children for Diabetes

While antibodies are molecules produced by the body's immune system to detect and destroy specific viruses, bacteria and other harmful substances, autoantibodies are antibodies that target a person's own healthy tissue. In the case of type 1 diabetes (T1D), a misdirected autoimmune response attacks the pancreas and gradually destroys the organ's insulin-producing beta cells. More...
11 Nov 2020
Image: The Qiagen miRNeasy serum/plasma miRNA isolation kit (Photo courtesy of Qiagen).

Molecular Blood Test Kit Detects Gastric Cancer Early

Gastric cancer (GC) is the fifth most common cancer and the third-leading cause of cancer deaths worldwide. GC mortality is high due to late presentation. In most countries, mass screening is neither feasible nor cost-effective because such screening methods are costly and invasive, with poor compliance. More...
09 Nov 2020
Image: The HM-JACKarc analytical system is a compact bench top system that uses Integrated Sphere Latex Turbidimetry to measure fecal hemoglobin concentration using a highly sensitive latex reagent coated with polyclonal antibodies to human hemoglobin (Photo courtesy of Hitachi Chemical Diagnostics Systems).

Fecal Immunochemical Test Assessed in Suspected Colorectal Cancer

Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine). Signs and symptoms may include blood in the stool, a change in bowel movements, weight loss, and fatigue. More...
05 Nov 2020
Image: A neural stem cell model of sporadic congenital hydrocephalus (Photo courtesy of Yale University School of Medicine).

Genetic Alterations Associated with Sporadic Congenital Hydrocephalus

Congenital hydrocephalus (CH), characterized by enlarged brain ventricles, is considered a disease of excessive cerebrospinal fluid (CSF) accumulation and thereby treated with neurosurgical CSF diversion with high morbidity and failure rates. More...
02 Nov 2020
Image: A sample collection kit for the expanded Multi-Cancer 83-gene comprehensive panel that increases diagnostic yield. Germline testing after tumor sequencing uncovers clinically actionable variants (Photo courtesy of Invitae).

Germline Testing After Tumor Sequencing Uncovers Clinically Actionable Variants

Genetic counseling and germline testing are recommended for patients with cancer who have suspected hereditary disease based on each patient’s presentation and family history. Separately, tumor DNA sequencing is increasingly used, most often in patients with advanced disease. More...
27 Oct 2020
Image: Circulating tumor cells (CTCs) are cancer cells that are released and disseminated into the bloodstream and lymphatic system. CTC cultures were successfully propagated from breast epithelial cells (Photo courtesy of Menarini Silicon Biosystems).

Novel CTC Culture Method Developed to Study Metastatic Cancer

Cancer metastasis is responsible for most cancer-associated death. During metastasis, cells that escape the primary tumor into the circulatory system are known as circulating tumor cells (CTCs). More...
26 Oct 2020
Image: Photomicrograph of histology of a Ewing sarcoma in lung. The PAS stain highlights glycogen and the staining was negative with a PAS diastase stain (Photo courtesy of Nephron).

Comprehensive Molecular Profiling Matches Pediatric Patients to Therapies

A major challenge of using a comprehensive profiling approach for precision medicine is separating pathogenic from non-pathogenic molecular changes within a tumor. More...
22 Oct 2020
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Antipsychotic TDM Assays
Saladax Antipsychotic Assays
Verification Panels for Assay Development & QC
Seroconversion Panels
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TORCH Infections Test
TORCH Panel
New
Multi-Function Pipetting Platform
apricot PP5


The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
Sekisui Diagnostics UK Ltd.