Pathology
Novel Inherited Mutation Predisposes Children to Medulloblastoma
Cancer genomics has revealed many genes and core molecular processes that contribute to human malignancies, but the genetic and molecular bases of many rare cancers remains unclear. Genetic predisposition accounts for 5% to 10% of cancer diagnoses in children. More...16 Apr 2020
Reactive Pneumocytes Identified by Distinctive Cytology
One of the most challenging and exceedingly common diagnostic dilemmas in pulmonary pathology is the distinction between reactive and neoplastic epithelial atypia. In particular, reactive pneumocytes in various infectious or inflammatory lung diseases can exhibit marked cytological atypia, which can closely resemble malignancy. More...15 Apr 2020
Susceptibility Gene Identified for Idiopathic Pulmonary Arterial Hypertension
Idiopathic pulmonary arterial hypertension (IPAH) is a lung disorder characterized by high blood pressure in the pulmonary arteries. In this instance, “idiopathic” means that the cause of the pulmonary artery hypertension is unknown. More...14 Apr 2020
Liquid Biopsy Lung Cancer Screening Method Developed
Genomic blood tests for cancer screening and early detection have become the focus of attention in the molecular diagnostic space, though most activity so far has been either toward pan-cancer screening tools, or in a few other specific tumor types like colorectal cancer, where tests hope to vie against colonoscopy and existing stool-based methods. More...09 Apr 2020
Potential Microbial Markers Identified for Cervical Pre-Cancer Progression
Human papillomavirus (HPV) infection is one of the most common sexually transmitted infections. However, only a small percentage of high-risk (HR) HPV infections progress to cervical pre-cancer and cancer. The role of the cervicovaginal microbiome (CVM) in the natural history of HR-HPV has been investigated. More...08 Apr 2020
Early Prediction of Resistance to Tyrosine Kinase Inhibitors Reported
Epidermal growth factor receptor (EGFR) gene mutations that confer sensitivity to tyrosine kinase inhibitors (TKI) in non-small cell lung carcinomas paved the way for a precision medicine approach in this neoplastic form. More...31 Mar 2020
Urine-Based Kidney Transplantation Rejection Risk Assay Launched
For kidney transplant recipients, prompt and accurate detection of transplant rejection is vital for timely intervention. Unfortunately, the gold standard for diagnosis of rejection is kidney biopsy, an invasive procedure. More...30 Mar 2020
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In Other News
Genetic Testing Benefits Postmenopausal Women with Breast Cancer
Multitarget Stool DNA Predicts Colorectal Neoplasia
Liquid Biopsy Assays Target Mutations and Improves Recurrence Prediction
EGFR Mutation Assay Cartridges Evaluated
Prognostic Values of Platelet Parameters in Gynecological Tumors Patients
Combining Biomarkers Predicts Metastasis in Medullary Thyroid Carcinoma
Neurofibromatosis Gene and Breast Cancer Resistance to Hormone Therapy
Combined Biopsy Method Improves Prostate Cancer Diagnosis
Blood-Based MicroRNA Signatures Distinguishes Individuals with Lung Cancer
Gut Bacteria Linked to Pulmonary Artery Hypertension
Blood Test Predicts Response to Immunotherapy in Metastatic NSCLC
Esophageal Cancer Precursor Detected by Electronic Nose Device
Heterogeneous Populations of Melanoma Circulating Tumor Cells Detected
Severe Strongyloidiasis Infection Reported in Kidney Transplant Recipients
Proteogenomic Characterization of Endometrial Carcinoma Analyzed
All-Digital Histopathology Attained by Infrared-Optical Hybrid Microscopy
Several Genes Linked to Long QT Syndrome Reappraised
Lung Adenocarcinoma Genomic Features Differ in East Asians, Europeans
Blood Test Lead to Earlier Detection of Gastrointestinal Cancers
Lung Cancer Liquid Biopsy Guides MRD-Directed Adjuvant Therapy
Single-Cell Sequencing Identifies Breast Cancer Risk
Heart Transplant Monitoring Test Validated
Microbiota’s Role Explored in Colorectal Cancer Among the Young
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.