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Pathology

Image: Petri dish culture plate with bacterial colonial growth of Prevotella spp., The men with cancer had increased levels Prevotella-9 (Photo courtesy of Dr. V.R. Dowell)

Gut Microbiota Differ in Men With Prostate Cancer

Gut microbiota are the collection of microbes in the gastrointestinal tract and they affect processes and mechanisms in the body. The state of gut microbiota has been linked to many conditions, even in organs that are far from the intestines, but their role in prostate cancer is not understood. More...
06 Jul 2022
Image: Photomicrograph of histology stained preparation showing a non-small cell lung carcinoma (Photo courtesy of Wikipedia/Librepath)

Pan-Cancer Analysis of Tumor Mutations Points to Predictive Biomarkers

Quantifying the effectiveness of different cancer therapies in patients with specific tumor mutations is critical for improving patient outcomes and advancing precision medicine. A key goal of precision medicine is to characterize how patients with specific genetic mutations respond to therapies. More...
05 Jul 2022
Image: New data demonstrates promise of novel extracellular vesicle biomarker-based approach for early cancer detection (Photo courtesy of Mercy BioAnalytics)

Assay Uses Novel Method for Early Detection of Ovarian Cancer

A new assay that uses a novel method of analyzing biomarkers based on individual extracellular vesicles (EVs) has substantially outperformed CA125 when distinguishing patients with early-stage high-grade serious ovarian cancer (HGSOC) from women with benign conditions. More...
05 Jul 2022
Image: New digital biomarker assay identifies patients with expression of HER2 in breast cancer (Photo courtesy of Paige)

Digital Biomarker Assay Identifies Breast Cancer Patients with Low Expression of HER2 Protein

A new AI software can identify patients with breast cancer whose tumors have expressions of human epidermal growth factor receptor 2 (HER2) protein, with results generated rapidly at the click of a button. More...
05 Jul 2022
Image: VENTANA DP 600 slide scanner (Photo courtesy of Roche Diagnostics)

Next-Gen, High-Capacity Slide Scanner for Digital Pathology to Help Diagnose Cancer

A new, high-capacity slide scanner creates high-resolution, digital images of stained tissue samples that help to diagnose cancer and determine a patient’s treatment. More...
29 Jun 2022
Image: Neuronal marker positivity in the middle frontal and inferior temporal gyrus of human post-mortem brains with common tauopathies (Photo courtesy of University of California San Francisco)

Caspase-6-Cleaved Tau is Relevant in Alzheimer's Disease

Alzheimer’s disease (AD) is characterized by the formation of aggregates of the tau protein in brain cells called neurofibrillary tangles. Although deposits of the amyloid β-protein are also found in AD brains, some scientists think that the tau protein aggregates are primarily responsible for the development of AD. More...
27 Jun 2022
Image: Colonic biopsy with features of collagenous colitis. Trichrome stain highlights irregular subepithelial collagen with entrapment of capillaries and inflammatory cells (Photo courtesy of Catherine E. Hagen, MD)

Appendectomy Linked to Higher Risk of Microscopic Colitis

The most common symptom of microscopic colitis is chronic, watery, non-bloody diarrhea. Episodes of diarrhea can last for weeks, months, or even years. However, many people with microscopic colitis may have long periods without diarrhea. More...
23 Jun 2022
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.