Pathology

Autoantibody Timing Predicts Genetically At-Risk Children for Diabetes
While antibodies are molecules produced by the body's immune system to detect and destroy specific viruses, bacteria and other harmful substances, autoantibodies are antibodies that target a person's own healthy tissue. In the case of type 1 diabetes (T1D), a misdirected autoimmune response attacks the pancreas and gradually destroys the organ's insulin-producing beta cells. More...11 Nov 2020

Molecular Blood Test Kit Detects Gastric Cancer Early
Gastric cancer (GC) is the fifth most common cancer and the third-leading cause of cancer deaths worldwide. GC mortality is high due to late presentation. In most countries, mass screening is neither feasible nor cost-effective because such screening methods are costly and invasive, with poor compliance. More...09 Nov 2020

Fecal Immunochemical Test Assessed in Suspected Colorectal Cancer
Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine). Signs and symptoms may include blood in the stool, a change in bowel movements, weight loss, and fatigue. More...05 Nov 2020

Genetic Alterations Associated with Sporadic Congenital Hydrocephalus
Congenital hydrocephalus (CH), characterized by enlarged brain ventricles, is considered a disease of excessive cerebrospinal fluid (CSF) accumulation and thereby treated with neurosurgical CSF diversion with high morbidity and failure rates. More...02 Nov 2020

Germline Testing After Tumor Sequencing Uncovers Clinically Actionable Variants
Genetic counseling and germline testing are recommended for patients with cancer who have suspected hereditary disease based on each patient’s presentation and family history. Separately, tumor DNA sequencing is increasingly used, most often in patients with advanced disease. More...27 Oct 2020


In Other News
Urine-Based Liquid Biopsy Test Detects Urothelial Carcinoma
Breath Test Developed for Head and Neck Cancer Diagnosis
Lymphocytic Infiltration Explored as Biomarker for Stable Colorectal Tumors
Hematological Biomarkers Predict Prognosis in Hepatocellular Carcinoma
HPV, p16 Offers Different Prognostic Clues in Oropharyngeal Cancer
Serum Thyroglobulin Assays Compared for Differentiated Thyroid Carcinoma
Epigenetic Markers Predict Type 2 Diabetes Patients Response to Metformin
New Diagnosed Anemia Linked to Crohn’s Disease Risk
Genomic Copy Number Predicts Esophageal Cancer Years Before Transformation
Circulating Tumor DNA Analysis Directs Therapy in Breast Cancer
Gut Microbiome Data Helps Routine Screening of Cardiovascular Disease
Genetics Influence Risk for Spontaneous Coronary Artery Dissection
Sequencing Could Augment Other Newborn Screening Methods
Jagged Ends of Double-Stranded DNA Characterized
Diabetes Blood Markers Linked to Alzheimer’s Disease Pathology
Saliva Test Fast Tracks Heart Attack Diagnosis
Pan-Cancer Study Reveals Extrachromosomal DNA Frequency
Adaptive Immune Cells in Ulcerative Colitis Revealed by Single-Cell Analyses
Cancer-Associated T Cell Receptors Evaluated for Malignancy Detection
Single-Cell Analysis Provides New Insights into Mitochondrial Diseases
Prostate Cancer Identified By Profiling Immune Cell Subsets
Circulating tumor DNA Test Predicts Immunotherapy Response
Renal Expression of Immunomodulators in Diabetic Nephropathy
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.