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Technology

Image: A mobile phone app called HandLens was designed to read and report paper strip SHERLOCK results (Photo courtesy of Anna Lachenauer, Stanford University School of Medicine)

Rapid CRISPR/Cas Assay for Diagnosis of Viral Fevers in Low-Tech Environments

Rapid diagnostic tests for Ebola and Lassa fever viruses based on the RNA-targeting CRISPR/Cas13a complex have been tested successfully under field conditions in several African countries. More...
07 Sep 2020
Image: A magnified image captured by the device used to perform the STAR (single telomere absolute-length rapid) assay. Different fluorescent intensities reflect the length variations in individual telomere molecules (Photo courtesy of National University of Singapore).

Streamlined Method for Telomere Length Measurement Opens New Cancer Diagnostic Opportunities

In a novel approach to cancer diagnosis, researchers have developed a high-throughput digital real-time PCR method for rapidly measuring the absolute lengths and quantities of individual telomere molecules. More...
01 Sep 2020
Image: De novo prediction of cancer-associated T cell receptors for noninvasive cancer detection (Photo courtesy of UT Southwestern Medical Center).

Cancer-Associated T Cell Receptors Evaluated for Malignancy Detection

A key goal in oncology is diagnosing cancer early, when it is more treatable. Despite decades of progress, early diagnosis of asymptomatic patients remains a major challenge. Most methods for this involve detecting cancer cells, but a different approach, focused on the body’s immune response. More...
31 Aug 2020
Image: The CDC 2019 Novel Coronavirus (2019-nCoV) Real-Time Reverse Transcriptase (RT)–PCR Diagnostic Panel detects the SARS-CoV-2 virus in upper and lower respiratory specimens. The new P-BEST approach provides both an eight-fold improvement in testing efficiency as well as an eight-fold reduction in cost of PCR testing (Photo courtesy of Center for Disease Control and Prevention)

New Pooling Strategy Increases Efficiency and Reduces Cost of COVID-19 PCR Tests

A new way of manipulating samples for COVID-19 testing of asymptomatic and symptomatic individuals provides both an eight-fold increase in testing efficiency, as well as an eight-fold reduction in test costs. More...
31 Aug 2020
Image: Schematic diagram of the OvCa-Chip microsystem that recreates vascular endothelium–mediated platelet extravasation in ovarian cancer (Photo courtesy of Texas A&M College of Engineering).

Microfluidic Device Explores Ovarian Cancer Interactions

In many cancers, platelet interactions with circulating tumor cells and their role in metastasis have been studied extensively. In ovarian cancer, platelet extravasation into the tumor and resulting metastasis is thought to be regulated mostly by the vascular endothelium. More...
26 Aug 2020
The TriVersa NanoMate LESA uses chip-based electrospray ionization technology that combines the benefits of liquid chromatography, mass spectrometry, chip-based infusion, fraction collection, and direct surface analysis into one integrated ion source platform (Photo courtesy of Advion BioSciences).

Nanoparticle System Captures Heart-Disease Biomarker From Blood

Physicians currently use an antibody-based test called enzyme-linked immunosorbent assay (ELISA) to help diagnose heart attacks based on elevated levels of cardiac troponin I (cTnI) in the patient's blood sample. While the ELISA test is sensitive, patients can have high levels of cTnI in the blood without having heart disease, which can lead to expensive and unnecessary treatments for patients. More...
20 Aug 2020
Cells in wells of a 96 well-plate before (A) and after (B) lysis cell by Direct PCR (B1) and Chelex100 (B2) (Photo courtesy of University Hospital Hamburg‐Eppendorf).

Two Simple Methods Prepare DNA Suitable For Digital PCR

Although DNA of high quality can be easily prepared from cultured cells with commercially available kits, many studies involve a large number of samples which increases the cost drastically. More...
19 Aug 2020
New
Gold Member
Clinical Chemistry Assay
Sorbitol Dehydrogenase (SDH)
POC Helicobacter Pylori Test Kit
Hepy Urease Test
New
HPV Molecular Test
BD Onclarity HPV Assay
New
CMV CLIA Diagnostic
CLIA CMV IgA Screen Group


LabMedica's Lab Technology channel informs on laboratory medicine techniques, while keeping an eye on new hardware, LIM software, consumables, and lab trends, techniques and safety.