Technology

Developed Immunoassay Predicts Benefits of Anti-PD-1 Therapy in NSCLC
Lung cancer is the most common cause of cancer-related deaths worldwide. However, current targeted therapies and immunotherapies have gradually improved patient survival. Anti-programmed cell death-1 (PD-1) antibodies (Abs) are key drugs in non-small-cell lung cancer treatment; however, clinical benefits with anti-PD-1 monotherapy are limited. More...12 May 2021
Holographic Histopathology Enables Fast, Precise Diagnostics
Microscopic assessment of biopsied and resected tissues is central to understanding the underlying pathophysiology and clinical states of many patients. Because most microscopic specimens are translucent to visible light, conventional histological methods achieve image contrast using exogenous labels. More...10 May 2021

A Novel Capsule-Based Smell Test for Diagnosis of Neurological and Respiratory Diseases
To aid in diagnosing diseases where loss of the sense of smell is a symptom, such as in chronic neurological conditions like Parkinson's and Alzheimer's diseases and in acute respiratory infections such as that caused by COVID-19, a team of researchers at Queen Mary University of London (United Kingdom) developed a novel smell testing kit based on capsules of aromatic oils placed between two strips of single-sided tape. More...10 May 2021
Spatial Tissue Profiled by Imaging-Free Molecular Tomography
Spatially resolved molecular atlases help scientists understand where different types of cells are located in the body and map their gene expression in specific locations in tissues and organs. However, many sequencing modalities lack spatial counterparts. More...06 May 2021
Different Methods Compared for Isolating Fungal DNA
Mucormycosis (previously called zygomycosis) is a serious, but rare fungal infection, caused by a group of molds called mucormycetes. These molds live throughout the environment. Mucormycosis mainly affects people who are immunocompromised or diabetic. More...26 Apr 2021

Breath Test Determines Severity of Methylmalonic Acidemia Disease
Methylmalonic acidemia is a disorder in which the body cannot break down certain proteins and fats. The result is a buildup of a substance called methylmalonic acid in the blood. This condition is passed down through families and is one of several conditions called an "inborn error of metabolism." More...20 Apr 2021

Breast Cancer Histopathology Employs Infrared Spectroscopic Imaging
Digital analysis of cancer specimens using spectroscopic imaging coupled to machine learning is an emerging area that links spatially localized spectral signatures to tissue structure and disease. Breast histopathology, as an example of the broad relevance of these techniques, is critically important for clinical diagnoses. More...19 Apr 2021
In Other News
Immunoassay Developed for Quantitative Detection of Serum Interleukin‐6
NMR-Based Method Measures Circulating Blood Citrate Levels
PCR Method Identifies Microsatellite Instability in Tumor-Derived Samples
Epidermal Patch Simultaneously Monitors Hemodynamic and Metabolic Biomarkers
Hemoglobin Levels Measured with AI Microscope, Microfluidic Chips
Magneto-Optical Diagnosis Evaluated for Symptomatic Malaria
Pulse-Controlled Amplification Tested for Infectious Disease Diagnostics
Biosensing Microneedle Patch Quantifies Biomarkers in Interstitial Fluid
Automated Urine Microscopy Analyzer Detects Uropathogen Morphology
MALDI-TOF-MS Evaluated for Rapid Diagnosis of Bacteremia and Fungemia
Novel Biomarker Candidate for Amyotrophic Lateral Sclerosis Explored
Quick Ultra-Sensitive System Identifies Multidrug-Resistant Bacteria
Lab-on-a-Chip Infection Test Provides Cheaper, Faster Portable Diagnostics
Interstitial Fluid Sampled from Skin Using a Microneedle Patch
Nanodiamonds Dramatically Boost Immunoassay Sensitivity
Fast Antibacterial Susceptibility Testing by Measuring Electron Transfer Metabolism
Breath Ammonia Biomarker Predicts Kidney Function in CKD Patients
Paper Diagnostic Directly Measures Fibrinogen in Whole Blood
Fecal Immunochemical Test Assessed in Suspected Colorectal Cancer
Artificial Enzyme Increases Sensitivity of Alzheimer's Disease Immunoassay
Single-Molecule Tethering Detects Nucleic Acids and Microorganisms
New Technology Rapidly Diagnoses Sickle Cell Disease
An Electrochemical Bio-barcode Device for Home Disease Monitoring and Diagnosis
LabMedica's Lab Technology channel informs on laboratory medicine techniques, while keeping an eye on new hardware, LIM software, consumables, and lab trends, techniques and safety.








