Technology
A New Image for Cell Sorting Introduced
Methods that physically separate cells of interest on the basis of measurable characteristics have numerous uses in clinical studies and applications, including cellular therapies. Cells can also be sorted on the basis of signals from extrinsic probes. More...10 May 2022
Novel Automated Procalcitonin Immunoassay Compared with Four Different Assays
Procalcitonin (PCT) is an important biomarker of sepsis and respiratory infections. An increase in PCT expression in parenchymal tissue can typically be observed in severe bacterial, but not or significantly less, respectively, in viral infections; thus, measurement of plasma PCT concentrations is an important diagnostic tool for clinicians to distinguish between infections from a bacterial versus viral origin. More...05 May 2022
Magnetic Needle Performs Less Invasive, More Precise Surgery and Diagnostic Tests
A team of researchers at the Johns Hopkins Whiting School of Engineering (Baltimore, MD, USA) have demonstrated for the first time that untethered magnetic needles can be forceful enough to accomplish surgery. The researchers call their device the "Pulse Actuated Collisions for Tissue-penetrating Needle," or MPACT-Needle. More...25 Apr 2022
Electronic Nose Technology May Facilitate Accurate Diagnosis of Sarcoidosis
Sarcoidosis is a granulomatous inflammatory disease without a known cause that can affect roughly any organ. The lungs are involved in the vast majority of patients (89% to 99%). Diagnosis can be challenging because no standardized diagnostic procedure exists. The three major criteria for diagnosis are compatible clinical features, pathology tissue assessment, and exclusion of other granulomatous diagnoses. More...12 Apr 2022
New Fluorescent DNA Label Reveals Nanoscopic Cancer Features
Researchers have developed a new fluorescent label that gives a clearer picture of how DNA architecture is disrupted in cancer cells. The findings could improve cancer diagnoses for patients and classification of future cancer risk. More...15 Mar 2022
Clinical Application of Leukocyte Counts Based on Targeted DNA Methylation Analysis (
Differential leukocyte counts are usually measured based on cellular morphology or surface marker expression. It has recently been shown that leukocyte counts can also be determined by cell-type–specific DNA methylation (DNAm). Such epigenetic leukocyte counting is applicable to small blood volumes and even frozen material, but for clinical translation, the method needs to be further refined and validated. More...14 Mar 2022
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In Other News
Paper-Based Portable Diagnostic Platform Accurately Detects Mosquito-Borne Diseases Under Field Conditions
Single Channel Pipetting Module Enables Hands-Free Transfers from Individual Tubes or Wells
Micro-Mechanical Blood Clot Testing Using Smartphones
P-O-C Assay Detects Respiratory Syncytial Virus in Older Adults
CRISPR-based Assay Platform Detects Multiple Viruses and COVID-19 Variants
Rapid COVID Test Developed Solves Problems With LAMP Sensitivity
RNA Sequencing Improves Gene Fusion Detection for Childhood Cancer Diagnostics
Automating Blood Smears Developed for Easier Malaria Diagnosis
High-Speed Fluorescence Image-Enabled Cell Sorting Tested
Immuno-CRISPR Assay Helps Diagnose Early Kidney Transplant Rejection
MCDA-LFB Assay Developed for Rapid Detection of Legionnaires’ Disease
Nomograms Including Rapid Antigen Test Detects Primary Bladder Cancer
Benchtop Cell Sorter Validated in Biosafety Containment Setting
3D Imaging Method Determines Prostate Cancer Aggressiveness
Rapid, Highly Accurate Test Developed to Detect Viruses
Rapid Diagnostic Testing Analyzed in Suspected Meningitis Diagnosis
Assay Developed for Patient-Specific Monitoring and Treatment for Ovarian Cancer
Point-of-Care Device Accurately Rapidly Diagnoses Sickle Cell Disease
PerkinElmer’s New Cloud-Based Platform Enables Laboratory Personnel to Remotely Manage Its Instruments in Real-Time
Breath Test Can Identify COVID-19 in Critically Ill Patients
Near-Infrared Set-Up Evaluated for Dried Blood Spot Hematocrit
Non-Invasive Nasal Swab Test Leverages Advanced Genomic Technology to Detect Lung Cancer Risk
Novel Cardiovascular Biomarker Secretoneurin Implicated in Arrhythmogenesis
LabMedica's Lab Technology channel informs on laboratory medicine techniques, while keeping an eye on new hardware, LIM software, consumables, and lab trends, techniques and safety.