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Microbiology

Image: Colored transmission electron microscopy of the coronavirus. SARS-CoV-2–positive sputum and feces was found after conversion of pharyngeal samples in patients with COVID-19. This virus was isolated from the fecal matter of a patient with diarrhea (Photo courtesy of BSIP/UIG)

SARS-CoV-2 Found in Sputum/Feces After Negative Pharyngeal Specimens

The outbreak of coronavirus disease 2019 (COVID-19) has become a global public health problem. In the absence of a specific therapy or vaccine, timely diagnosis and the establishment of a sufficient isolation period for infected individuals are critical to containment efforts. More...
14 Apr 2020
Image: Photomicrograph of a vaginal epithelial clue cell coated with Gardnerella vaginalis (Photo courtesy of Universidad Autónoma de Zacatecas).

Potential Microbial Markers Identified for Cervical Pre-Cancer Progression

Human papillomavirus (HPV) infection is one of the most common sexually transmitted infections. However, only a small percentage of high-risk (HR) HPV infections progress to cervical pre-cancer and cancer. The role of the cervicovaginal microbiome (CVM) in the natural history of HR-HPV has been investigated. More...
08 Apr 2020
Image: The Oxford Nanopore MinION device (Photo courtesy of Oxford Nanopore Technologies).

Deep Throat SARS-CoV-2 Viral Load Ascertained in Saliva Samples

Posterior oropharyngeal saliva samples are a non-invasive specimen more acceptable to patients and health-care workers. Unlike severe acute respiratory syndrome, patients with COVID-19 had the highest viral load near presentation, which could account for the fast-spreading nature of this epidemic. More...
06 Apr 2020
Image:  The SpectraMax M5 Microplate Reader is the standard for UV/visible multi-mode reader absorbance, providing ultrafast, full spectral range detection for cuvettes, 96-, and 384-well microplates (Photo courtesy of Molecular Devices).

Novel Rapid Test Developed for Detecting Carbapenemase

As a potent β-lactamase, carbapenemase can degrade almost all β-lactam antimicrobial drugs, including the carbapenems, regarded as the last line of therapy for many life-threatening infections. If uncontrolled, the spread of these carbapenemases is expected to increase therapeutic failure and leave many patients with no effective treatment options. More...
02 Apr 2020
Image: The image shows bacterial cells trapped in a three-dimensional microbead matrix (Photo courtesy of Wenrong He, Rochester Institute of Technology)

Novel Nanofluidic Device Traps and Concentrates Pathogenic Bacteria

 A nanofluidic device containing stacked magnetic beads of different sizes has been developed to efficiently trap, concentrate, and retrieve Escherichia coli (E. coli) bacteria from liquid suspensions. More...
31 Mar 2020
Image: Factors associated with acute respiratory distress syndrome (ARDS) In COVID-19 identified (Photo courtesy of the Brian Orelli, PhD).

Factors Associated with ARDS in COVID-19 Identified

 Patients with COVID-19 present primarily with fever, myalgia or fatigue, and dry cough. Although most patients are thought to have a favorable prognosis, older patients and those with chronic underlying conditions may have worse outcomes. More...
30 Mar 2020
Image: Transmission electron micrograph of an isolate from a case of COVID-19, caused by the coronavirus SARS-CoV-2. The spherical viral particles, colorized blue, contain cross-sections through the viral genome, seen as black dots (Photo courtesy of Hannah A Bullock and Azaibi Tamin).

SARS-Cov-2 Specific Antibody Responses in COVID-19 Patients

 The rapid identification of the etiology and the sharing of the genetic sequence of the virus, followed by international collaborative efforts initiated due to the emergence of SARS-CoV-2 have led to the rapid availability of real-time PCR diagnostic assays that support the case ascertainment and tracking of the outbreak. More...
30 Mar 2020
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.
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