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Immunology

Image: The UniCel DxI 800 immunoassay system (Photo courtesy of Beckman Coulter).

Thyroid Disorders Affect Circulating TRAIL Levels

A circulating protein called TNF-related apoptosis-inducing ligand (TRAIL) might have a role in the regulation of body weight and metabolism. Interestingly, thyroid hormones seem to increase TRAIL tissue expression. More...
12 Jun 2017
Image: The Navios flow cytometer (Photo courtesy of Beckman Coulter).

Panel Developed for Immunophenotyping Lymphocytes

A lymphoproliferative disorder screening tube (LPD-ST) has been developed with the aim to provide comprehensive immunophenotyping of lymphocyte subsets with minimal need for additional testing. More...
07 Jun 2017
DIASOURCE (A Biovendor Company)
Image: The complete extraction-free, fully automated Liaison XL 1,25 dihydroxyvitamin D radioimmunoassay kit (Photo courtesy of DiaSorin).

Vitamin D Assays Compared and Harmonized

There are a variety of assay techniques available to measure of 25-hydroxyvitamin D (25(OH)D) concentrations and some have the ability to measure the two forms 25(OH)D2 and 25(OH)D3. However, there are significant discrepancies between procedures used to estimate vitamin D status. More...
06 Jun 2017
Image: Immunohistochemistry (IHC) staining of human epidermal growth factor receptor 2 (HER2) in biopsy specimens showing intratumoral homogeneity and heterogeneity (Photo courtesy of Fudan University).

Heterogeneity Influences Cancer Immunohistochemistry Results

Many gastric cancer (GC) patients are with inoperable lesions and endoscopic biopsy becomes the only available approach to obtain tumor tissues for human epidermal growth factor receptor 2 (HER2) assessment. Unlike resected specimens, biopsy specimens are influenced by many factors and in turn more difficult to manipulate. More...
06 Jun 2017
Image: A paper-based test strip could help people with heart failure know if their condition is worsening (Photo courtesy of the American Chemical Society).

Strip Test Enables Home Monitoring of Heart Condition

Heart failure can often be managed with medications and lifestyle changes, but its progression needs to be monitored closely to adjust treatment and prevent emergency room visits. Now scientists have developed a simple paper test strip that could potentially allow patients to monitor themselves for the first time. More...
05 Jun 2017
Image: Exhaled breath condensate is rapidly analyzed by a new graphene-based nanoelectronic sensor that detects nitrite, a key inflammatory marker in the inner lining of the respiratory airway (Photo courtesy of Azam Gholizadeh, Rutgers University).

Graphene-Based Sensor Helps Predict Asthma Attacks

Researchers have developed a prototype graphene-based device that detects inflammation in lungs, which could lead to earlier detection of asthma attacks and improve the management of asthma and other respiratory diseases, preventing hospitalizations and deaths. The invention helps pave the way for developing small wearable devices that could indicate when and at what dosage to take medication. More...
05 Jun 2017
Image: The T-Track CMV diagnostic ELISpot kit (Photo courtesy of Lophius Biosciences).

Assay Validated for CMV-Specific Immunity

Cytomegalovirus (CMV) is a major cause of infectious complications in immunocompromised individuals. Protection against CMV infection or reactivation is normally assured by both the innate and adaptive arms of the immune system. More...
30 May 2017
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Veterinary Hematology Analyzer
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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