Immunology
T Cells Recognize Recent SARS-CoV-2 Variants
Due to the proofreading ability of the coronavirus (CoV) RNA-dependent RNA polymerase, the evolution of the global SARS-CoV-2 viral population during the current pandemic has been relatively constrained as compared to other endemic RNA viruses that do not possess this ability. More...15 Apr 2021
Type 1 Diabetes Onset Preceded by Gene Expression Changes
Type 1 diabetes (T1D) results from insufficient insulin production and is thought to result from an immune reaction against the body’s own pancreatic β cells. The exact cause of T1D remains unknown, although asymptomatic islet autoimmunity lasting from weeks to years before diagnosis raises the possibility of intervention before the onset of clinical disease. More...14 Apr 2021
Serious Infections Prevalent in ANCA-Associated Vasculitis
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) are among the rheumatic diseases with the highest mortality and morbidity, due to their major multi-organ involvement (lungs, kidneys) and their relapsing nature requiring aggressive immunosuppressive treatment. More...08 Apr 2021
Immunoassay Developed for Quantitative Detection of Serum Interleukin‐6
Interleukin‐6 (IL‐6) is a multifunctional protein and is primarily produced by macrophages, monocytes, fibroblasts, and T lymphocytes, and plays important roles in immune regulation, hematopoiesis, inflammation, and tumorigenesis. More...07 Apr 2021
Performance of Five Lipoprotein(a) Immunoassays Evaluated
Increased serum Lipoprotein(a) [Lp(a)] is considered an independent, inherited risk factor for atherosclerotic cardiovascular disease (ASCVD), including myocardial infarction and stroke. This risk is believed to be due to pro-atherogenic, pro-inflammatory, and pro-thrombotic properties of the Lp(a) particle More...06 Apr 2021
Flow-Cytometric Expression of Endoglin Assessed in B-Acute Lymphoblastic Leukemia
Acute lymphoblastic leukemia (ALL) is a malignant disorder representing clonal expansion and arrest of maturation of lymphoid progenitor cells in the bone marrow, blood, and extramedullary sites. The incidence of ALL generally follows a bimodal distribution, with its first peak occurring in childhood and the second around the age of 50. More...01 Apr 2021
Toxoplasmosis Immune Status in Pregnancy Determined by Immunochromatography Assay
Toxoplasmosis is a disease that results from infection with the Toxoplasma gondii parasite, one of the world's most common parasites. Infection usually occurs by eating undercooked contaminated meat, exposure from infected cat feces, or mother-to-child transmission during pregnancy. More...30 Mar 2021
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In Other News
Toxoplasmic Encephalitis in HIV Patients Detected in Urine
Paraproteins Identification Methods Compared for Monoclonal Gammopathies
Chemiluminescence Anti‐Müllerian Hormone Assay Performance Characterized
Cardiac Troponins Assessed for Acute Heart Failure
Biomarker Protein Investigated in Juvenile Idiopathic Arthritis
Immune Response to Insulin Identifies Risk of Juvenile-Diabetes
Fibrinogen to Albumin Ratio Reflects ANCA‐Associated Vasculitis Activity
Rh Alloimmunization Explored in Chronically Transfused Thalassemia Patients
Blood Biomarker Predicts Dementia in Cerebral Small Vessel Disease
Urinary Antigen Test Kit Evaluated for Diagnosing Legionella Pneumonia
Proteogenomic And Metabolomic Studies Characterize Human Glioblastoma
T Cell Response Profiled in COVID-19 Patients
Biomarker Predicts Pancreatic Cancer Patients’ Response to CD40 Immunotherapy
Blood Test Distinguishes Epileptic Seizures From PNES
TFP Inhibitor Levels Elevated in Bleeding Tendency Patients
New Control Mechanism Discovered in Innate Immune System
Prolonged Maternal Zika Viremia Evaluated for Adverse Perinatal Outcomes
Early Plasma Biomarkers Discovered for Alzheimer's Disease
Proinflammatory T Cell Polarization Investigated in Early Knee Osteoarthritis
Alzheimer's Progression Tracked with Blood Biomarkers
Early Differences in Cytokine Production Distinguish Severity of COVID-19
Mismatch Repair/Microsatellite Instability Evaluated Using Cytology Effusion Specimens
Tryptophan Metabolism Is Dysregulated in Individuals with Fanconi Anemia
The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.