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Molecular Diagnostics

Image: The CFX96 real-time polymerase chain reaction detection system (Photo courtesy of Bio-Rad).

Fast Diagnosis of Sporotrichosis Based on RT-PCR

Sporotrichosis is a subacute or chronic infectious disease caused by dimorphic fungi of Sporothrix spp. The genus Sporothrix consists of several species with different geographic distributions, virulence, and antifungal susceptibilities, making species-level identification necessary. More...
21 Mar 2019
Image: A histopathology of clear cell papillary renal cell carcinoma (Photo courtesy of Nephron).

Five-Gene Signature Predicts Survival from Renal Cell Carcinoma

Papillary renal cell carcinomas include type 1 lesions, which are characterized by small cells in single layers and scanty cytoplasm and type 2 lesions, which are distinguished by larger cells, pseudo-stratified nuclei, and voluminous eosinophilic cytoplasm. More...
20 Mar 2019
Image: The TruSight Tumor 15 uses next-generation sequencing (NGS) technology to provide a comprehensive assessment of 15 genes that are commonly mutated in solid tumors (Photo courtesy of Illumina).

EBUS More Reliable Than Histology for Cancer Diagnoses

Radial probe endobronchial ultrasound (EBUS) is a minimally invasive procedure that improves localization of peripheral pulmonary lesions. Cytology samples of the suspect lesion site collected by radial EBUS bronchoscopy provides good diagnostic sensitivity estimated at 73%, whereas histology does not definitely diagnose malignancy in approximately 20% cases. More...
20 Mar 2019
Image: Researchers combined graphene with nano-sized metal ribbons of gold to create an ultrasensitive biosensor that could help detect a variety of diseases in humans and animals (Photo courtesy of Oh Group, University of Minnesota).

Researchers Lay Groundwork for Graphene-based Diagnostic Devices

A breakthrough in the use of graphene as a plasmon resonator for ultrasensitive infrared spectroscopy should enable development of new biosensors for detection of diseases at the molecular level. More...
18 Mar 2019
Image: A new study identified 76 new gene regions associated with sleep duration (Photo courtesy of CCO Public Domain).

New Genetic Loci Link to Insufficient and Excessive Sleep Duration

Genetic loci have been found that are linked to either abnormally long or short sleep duration. More...
18 Mar 2019
Image: A micrograph of pancreatic ductal adenocarcinoma (the most common type of pancreatic cancer) (Photo courtesy of Wikimedia Commons).

Genetic Markers Predict Susceptibility of Pancreatic Tumors

A panel of genetic markers allows clinicians to match pancreatic tumors with appropriate existing chemotherapeutic drugs. More...
18 Mar 2019
Image: A mouth ulcer (in this case associated with aphthous stomatitis) on the labial mucosa (lining of the lower lip) (Photo courtesy of Wikimedia Commons).

Study Identifies Gene Variations for Mouth Ulcers

An extensive genome-wide association study (GWAS) identified 97 common genetic variations that predisposed people to suffer from mouth ulcers. More...
18 Mar 2019
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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