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Molecular Diagnostics

Image: The AU480 is the ideal main clinical chemistry analyzer for small- to medium-sized laboratories (Photo courtesy of Beckman Coulter).

Side Effects of BP Drugs Genetically Determined

Thiazide diuretics are one of the most widely used and effective class of medications used to treat high blood pressure, and is highly effective at preventing heart attacks and strokes in patients with hypertension. More...
07 Sep 2017

Image: The NanoDrop 1000 spectrophotometer used for quantification and purity assessment of RNA samples (Photo courtesy of Thermo Fisher Scientific).

Blood Test Predicts Prostate Tumor Resistance

Prostate cancer (PCa) is the most common cancer and the third leading cause of cancer death among European men. In metastatic PCa progression from a hormone-sensitive state to castration resistance under androgen deprivation therapy marks the transition to the lethal phenotype of the disease. More...
07 Sep 2017

Liquid Biopsy Panel Yields Complete Molecular Profile

The first liquid biopsy pan-cancer panel that simultaneously interrogates exosomal ribonucleic acid (exoRNA) and circulating tumor DNA (ctDNA) in a single assay has been launched. More...
06 Sep 2017

Novel PCR Test Detects H. Pylori Drug Resistance

An estimated one million new cases of gastric cancer and 720,000 gastric cancer related deaths occur worldwide each year. Helicobacter pylori is a Group 1 carcinogen that is responsible for approximately 89% of lower stomach gastric cancer cases. More...
06 Sep 2017

$Image: A newly developed molecular test could detect Alzheimer\'s disease at a pre-symptomatic state. The results indicated that multivariate analysis of transcripts in blood samples can provide an accurate and minimally invasive strategy for diagnosis of AD and early detection of AD risk (Image courtesy of Arizona State University; Graphic by Jason Drees).$

Molecular Blood Test Could Identify Alzheimer's

A new multivariate molecular test is being developed that includes testing for genes to identify people at risk of developing Alzheimer’s disease (AD) and testing of peripheral blood leukocyte RNA transcripts to provide early diagnosis of people with AD. The new method distinguished between Alzheimer’s, Parkinson’s, and healthy controls, indicating that it can pick out AD from other degenerative brain conditions. More...
06 Sep 2017

Image: Staining of human cell line U-2 OS with fluorescently labeled SP110 antibody shows localization of the protein to the nucleus (Photo courtesy of Novus Biologicals).

New Assay Facilitates Diagnosis of Rare Infant Disease

A novel flow cytometric assay that is easily performed in diagnostic laboratories was developed to improve the ability to diagnose the rare syndrome, hepatic veno-occlusive disease with immunodeficiency (VODI). More...
05 Sep 2017

Image: Paper-based diagnostic device that detects biomarkers and identifies diseases by performing electrochemical analyses. The assays change color to indicate specific test results. The device can be plugged into the handheld potentiostat, at left (Photo courtesy of Purdue University, Aniket Pal).

Disposable POC Device Introduced for Low-Resource Areas

A recent paper described a novel diagnostic device fabricated from various types of paper to be used for point-of-care testing in areas lacking electricity and other resources. More...
05 Sep 2017

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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.