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Molecular Diagnostics

Image: A diagram of simplifying disease diagnosis using topically applied nanotechnology could change the way skin diseases such as abnormal scars are diagnosed and managed (Photo courtesy of Nanyang Technological University).

Topical Nanotechnology Simplifies Skin Disease Diagnosis

Tissue biopsies are necessary for the accurate diagnosis of skin diseases, but their application is limited by the pain, inconvenience, and morbidity experienced by patients, as well as risks of scarring and infection. More...
30 May 2018
Image: A blood transfusion bag typed for A Rh negative (Photo courtesy of Sherry Yates Young).

Sequencing Enables Precise Match for Blood Transfusions

There are more than 300 known red blood cell (RBC) antigens and 33 platelet antigens that differ between individuals. Sensitization to antigens is a serious complication that can occur in prenatal medicine and after blood transfusion, particularly for patients who require multiple transfusions. More...
30 May 2018
Image: The IsoPSA is a new blood test for the accurate prediction of overall risk of malignant prostate cancer (Photo courtesy of the Cleveland Clinic).

New Test More Accurate for Determining Prostate Cancer Risk

A new blood test for determination of prostate cancer risk was found to be more accurate than the current gold standard PSA (prostate specific antigen) test. More...
29 May 2018
Image: A laboratory setup used to test exosomes extracted from blood samples for pancreatic cancer biomarkers (Photo courtesy of the University of California, San Diego).

Electronic Chip Captures Pancreatic Cancer Exosomes for Analysis

A novel electronic chip-based method for rapid capture and analysis of exosomes together with their protein and other biomarker content will facilitate liquid biopsy diagnosis of pancreatic cancer. More...
29 May 2018
Image: The Cervista HPV HR assay, a cervical cancer rapid diagnostic test for human papillomavirus (HPV) (Photo courtesy of Hologic).

Study Shows Labs Should Specify HPV Assay Used

Human papillomavirus (HPV) is a double-stranded DNA virus that infects squamous and glandular epithelial cells in the ectocervix and endocervix and integrates its genome into the host DNA, causing either an active or a latent infection without detectable symptoms. More...
24 May 2018
Image: The TruSeq DNA PCR-free assay kits: Simple, all-inclusive whole-genome sequencing (WGS) library preparation that provides accurate and comprehensive coverage of complex genomes (Photo courtesy of Illumina).

Genome Sequencing Increases Sensitivity of Carrier Screens

Traditionally, carrier screening has focused on specific disorders that are known to have a higher prevalence in certain ethnic populations. More recently, lower sequencing costs coupled with higher accuracy of next generation sequencing-based methodologies have made it affordable for clinical laboratories to offer screening for substantially more conditions. More...
23 May 2018
Image: A photomicrograph of breast cancer cells in purple surrounded by healthy tissue in pink (Photo courtesy of US National Institute of Health).

Hereditary Breast Cancer Tests Double Detection Rate

Germline genetic testing in patients newly diagnosed with cancer has the potential to reduce disease burden through secondary prevention and targeted therapies. There is a prerequisite to understand how genetic testing is being integrated into practice for patients newly diagnosed with cancer and the impact of results on treatment decisions. More...
23 May 2018
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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