Molecular Diagnostics

Image: A histological micrograph showing endometrium with abundant plasma cells, which are diagnostic for chronic endometritis and scattered neutrophils (Photo courtesy of Nephron).

Molecular Diagnostic Tool Developed for Chronic Endometritis

Chronic endometritis is a persistent inflammation of the endometrial mucosa caused by bacterial pathogens. Although chronic endometritis can be asymptomatic, it is found in up to 40% of infertile patients and is responsible for repeated implantation failure and recurrent miscarriage. More...
04 Apr 2018

Image: A graphic comparison of a healthy joint and osteoarthritis (Photo courtesy of European Union Cordis).

New Osteoarthritis Genes Discovered

Almost nine million people in the UK suffer from osteoarthritis, a degenerative joint disease in which a person's joints become damaged, stop moving freely and become painful. Osteoarthritis is the most prevalent musculoskeletal disease and a leading cause of disability worldwide. More...
04 Apr 2018

Urinary Gene-Based Test Detects Bladder Cancer

Predominantly of urothelial histology, invasive bladder cancer (BC) arises from non-invasive papillary or flat precursors, and many BC patients suffer multiple relapses prior to progression, providing ample lead-time for early detection and treatment prior to metastasis. More...
03 Apr 2018

Cervical Fluid Test Developed for Gynecological Cancers

Together, endometrial and ovarian cancers account for about 25,000 deaths each year and are the third leading cause of cancer-related mortality in women in the USA. Most of these deaths are caused by high-grade tumor subtypes, which tend to metastasize before the onset of symptoms. More...
03 Apr 2018

$Image: In an outbreak of Legionnaires\' disease, finding the exact source as quickly as possible is essential to preventing further infections. Investigators have now developed a rapid test that identifies Legionella pneumophila in less than one hour. The photograph shows the use of the LegioTyper-chip with the MCR microarray analysis platform (Photo courtesy of Jonas Bemetz, Technical University of Munich).$