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Molecular Diagnostics

Image: A photomicrograph showing histopathological image of cerebral glioblastoma (Photo courtesy of Wikimedia Commons).

Biomarker Predicts Cancer Aggressiveness and Drug Susceptibility

Researchers have identified a protein required by some forms of brain cancer (glioblastoma multiforme, GBM) that can be used as a predictive marker for aggressiveness and effective drug response. More...
23 Oct 2017
Image: Mitochondrial DNA comprises the small circular chromosome found inside the mitochondria (Photo courtesy of the U.S. National Human Genome Research Institute).

Mitochondrial DNA Copy Number Improves CVD Risk Prediction

Mitochondrial DNA copy number (mtDNA-CN), which represents the number of mitochondria per cell and number of mitochondrial genomes per mitochondrion, is an indirect biomarker of mitochondrial function that has been identified as an independent predictor of cardiovascular disease (CVD) risk. More...
23 Oct 2017
Image: The Quantiflour dsDNA system for sensitive quantitation of double-stranded DNA in solution (Photo courtesy of Promega).

Bacterial Composition Linked to Breast Cancer

Breast cancer is the second most common cancer in women (after skin cancer) in the USA, where one in eight women will develop the disease in their lifetimes. Bacteria that live in the body is known as the microbiome, and influence many diseases. More...
19 Oct 2017
Image: A diagram of the preeclampsia placenta compared to a normal placenta (Photo courtesy of the University of Dundee).

Preeclampsia Triggered By Gene Activity

Preeclampsia affects around 4% of all pregnancies and its main symptoms are high blood pressure and protein in the urine. If these symptoms reach dangerous levels, delivery must be induced prematurely. More...
19 Oct 2017
Image: The structure of the TOP2A protein (Photo courtesy of Wikimedia Commons).

Gene Pair Distinguishes Forms of Prostate Cancer

Cancer researchers have identified a biomarker comprising a pair of genes that distinguishes between indolent and aggressive prostate cancers. More...
16 Oct 2017
Image: The microfluidic device SlipChip is designed to compartmentalize single molecules (Photo courtesy of SlipChip / CalTech).

Rapid Method Determines Antibiotic Susceptibility

A novel micro-fluidic device used a sensitive digital real-time loop-mediated isothermal amplification (dLAMP) assay to rapidly determine bacterial antibiotic susceptibility. More...
16 Oct 2017
Image: Clinical uses of Warfarin, a drug that is used for the treatment of existing blood clots and to prevent new blood clots formation inside the body (Photo courtesy of Dr. Manish Goyal).

Genetic Testing Determines Safest Dose of Blood Thinner

Warfarin, commonly known as Coumadin, is frequently used to prevent a life-threatening blood clot. It is often prescribed to people having hip or knee replacement surgery, as well as to individuals with certain heart conditions that leave them vulnerable to a stroke. More...
12 Oct 2017
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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