Molecular Diagnostics
Genetic Link Confirmed Between DCIS And Invasive Disease
Inherited genetic links have been confirmed between non-invasive cancerous changes found in the milk ducts, known as ductal carcinoma in situ (DCIS) and the development of invasive breast cancer, meaning that a family history of DCIS could be as important to assessing a woman's risk as a history of invasive breast cancer. More...28 Apr 2016
DNA-Based Test Determines Degree Of Liver Fibrosis
Non-alcoholic fatty liver disease (NAFLD) accounts for the majority of liver disease burden in the Western world. Liver biopsy remains the gold standard test to accurately stage fibrosis in patients with NAFLD, but it is invasive and carries risks. More...28 Apr 2016
Genomics Makeup of Colorectal Tumors Predicts Immune Response
A study based on whole-exome sequencing and immune response finds that colorectal cancers (CRCs) heavily bedecked with tumor-related neoantigens are likely to be permeated with disease-fighting white blood cells (WBCs). The discovery helps sharpen research into therapies that make tumors more vulnerable to such an attack and into companion diagnostics. More...27 Apr 2016
Pathway Implicated in Development of Eosinophilic Esophagitis
Scientists have identified a protein whose dysfunction appears to be involved in causing the tissue damage in patients with eosinophilic esophagitis (EoE). The finding may lead to improved pathology analysis, diagnostics, and specific drug therapies for patients. More...26 Apr 2016
Blood Test Detects Genetic Mutations in Lung Cancer
A simple blood test can rapidly and accurately detect mutations in two key genes in non-small-cell lung tumors, demonstrating the test's potential as a clinical tool for identifying patients who can benefit from drugs targeting those mutations. More...26 Apr 2016
Genetic Testing for Breast Cancer Patients Expanded
Next-generation sequencing (NGS) allows testing for mutations in additional breast cancer predisposition genes. The frequency of germline mutations detected by using NGS has been reported in patients with breast cancer who were referred for Breast Cancer Early Onset 1 and 2 (BRCA1/2) testing or with triple-negative breast cancer. More...21 Apr 2016
Blood Test Evaluated for Suspected Obstructive Coronary Artery Disease
Coronary artery disease (CAD) also known as ischemic heart disease is a very common heart condition in the USA and one in seven deaths among Americans is caused by CAD. A common symptom is chest pain or discomfort, which may travel into the shoulder, arm, back, neck, or jaw. More...21 Apr 2016
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DNA topoisomerase I ELISA
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In Other News
Association Found Between MC1R Variant and Melanoma Risk
Prostate Needle Biopsy Biomarker Predicts Tumor Aggressiveness
Gene Test Identifies Patients with High Risk Colon Cancer
Improved “Liquid Biopsy” Technique Enhances Tumor DNA Detection
Establishment of Biomarker Panel May Lead to Rapid Tests for Early Diagnosis of Pancreatic Cancer
Genomic Sequencing Identifies Deadly Bloodstream Infection
Noncoding RNA Gene Linked to Malignant Melanoma
Novel Blood Test Detects Colorectal Cancer Recurrence Earlier
Hereditary Cancer Test Identifies Deleterious Mutations in Endometrial Cancer
Multigene Test Identifies Early Breast Cancer
Blood Test Gives Early Warning of Melanoma Relapse
Robust Method Developed for Microbiome Analysis
Biomarker Identifies Uveal Melanoma Patients at Risk for Metastasis
Ultrasensitive Antibody Detection Enabled by Agglutination-PCR
Whole-Exome Sequencing Identifies Rare Inherited Diseases
Gene Predicts Outcomes for Head and Neck Patients
Genomic Analyses Identifies Molecular Subtypes of Pancreatic Cancer
Biomarkers Help Diagnose Mild Cognitive Impairment in Diabetics
New Protocol Rapidly Detects Three Legionella Species
Blood Test Developed to Detect Five Early-Stage Cancers
Blood Test Detects All Known Inherited Heart Conditions Genes
Tumor Biopsies with Blood Monitoring Show Lesion-Specific Response
Molecular Type 2 Diabetes Biomarker Identified
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.