Molecular Diagnostics

Mutations Disrupting Neuritogenesis Genes Confer Risk for Cerebral Palsy
Cerebral palsy (CP) is a group of permanent movement disorders that appear in early childhood. Signs and symptoms vary among people and over time. Often, symptoms include poor coordination, stiff muscles, weak muscles, and tremors. More...14 Oct 2020

Elevated Levels of Defective Mitochondrial DNA Predict Likelihood of Reproductive Success
A sperm biomarker has been found that may be able to supplement or replace the semen parameters that poorly predict reproductive success yet are the most prevalent diagnostic tool for male infertility. More...14 Oct 2020


Bacterium and Viral Coinfection Contributes to Postinfectious Hydrocephalus
Neonatal sepsis often precedes postinfectious hydrocephalus (PIH), although the manifestations of hydrocephalus typically emerge in the months after the neonatal period as sufficient cerebrospinal fluid (CSF) accumulates such that cranial expansion garners medical attention. More...12 Oct 2020

Elevated Levels of Lipoprotein(a) Predict Increased Risk for Developing Cardiovascular Diseases
Measurement of the blood biomarker lipoprotein(a) predicts risk of developing cardiovascular disease as well as determination of such standard factors as cholesterol and triglycerides. More...12 Oct 2020

Genome Sequencing Evaluated in Children with Unexplained Medical Complexity
Children with medical complexity (CMC) have at least one chronic condition, depend on a technological tool like a ventilator or require intravenous nutrition or drugs, are under the care of multiple subspecialists, and have substantial healthcare use. More...08 Oct 2020

Blood-Based Test Accurately Identifies Viral Infection Before Symptoms Develop
Acute viral infections are one of the most common reasons for visits to primary care physicians in high-income countries. The usefulness of traditional pathogen-focused diagnostic methods for viral infection (e.g., culture, serology, antigen detection, and PCR) is limited by the fact they can be slow, costly, and restricted in terms of breadth of pathogens detected. More...07 Oct 2020
In Other News
HPV, p16 Offers Different Prognostic Clues in Oropharyngeal Cancer
Bacteriophage Analysis Technique Reveals Details of COVID-19’s Impact on the Immune System
Large Genome-Wide Association Study Identifies Novel Abdominal Aortic Aneurysm Risk Loci
Smartphone Microscopic Method Detects Cryptosporidium and Giardia
Epigenetic Markers Predict Type 2 Diabetes Patients Response to Metformin
Endometrium Undergoes Gene Expression Shifts During Menstrual Cycle
Rapid One-Step Assay for Field-Based Detection of Asymptomatic Malaria
One-Step CRISPR-Based Assay Could Streamline COVID-19 Testing
Genomic Copy Number Predicts Esophageal Cancer Years Before Transformation
Paper-Based Microneedle Skin Patch for Continuous Glucose Monitoring
Circulating Tumor DNA Analysis Directs Therapy in Breast Cancer
A Paper-Based Nucleic Acid Testing Device for Rapid Diagnosis of Mosquito-Borne Viral Diseases
Click Chip’ Detects Early-Stage Liver Cancer Biomarkers in Extracellular Vesicles
Novel Rapid Lateral Flow Assay Measures Ovarian Cancer Biomarker CA125
Biosensing Platform Diagnoses Diseases Through Single Molecule Detection
Genetics Influence Risk for Spontaneous Coronary Artery Dissection
Proteomics-Based Diagnostic Test Predicts Risk of Dying from Staphylococcus aureus Bacteremia
Sequencing Could Augment Other Newborn Screening Methods
Jagged Ends of Double-Stranded DNA Characterized
MicroRNA-Based Liquid Biopsy Assay for Early Diagnosis of Head and Neck Cancer
New Diagnostic Test Assesses Suitability for Immune Checkpoint Inhibitor Immunotherapy
Loop-Mediated Isothermal Amplification Kit Detects Chagas Disease
Rapid CRISPR/Cas Assay for Diagnosis of Viral Fevers in Low-Tech Environments
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.








