Molecular Diagnostics
Urine-Based Liquid Biopsy Test Detects Urothelial Carcinoma
Urine cytology, which is widely used to screen for bladder cancer, has high specificity but lacks sensitivity, especially for low-grade cancers. Cystoscopy, while more accurate than cytology, is an invasive procedure with added costs and potential complications for the patient. More...22 Oct 2020
Analysis of Placental Cell Free DNA and RNA Predicts Gestational Complications
A recent paper revealed that circulating cell-free nucleic acids (DNA and RNA) shed from the placenta into the mother's blood during the first trimester of pregnancy could be used to predict potentially serious complications such as ischemic placental disease and gestational diabetes. More...20 Oct 2020
Mutations Disrupting Neuritogenesis Genes Confer Risk for Cerebral Palsy
Cerebral palsy (CP) is a group of permanent movement disorders that appear in early childhood. Signs and symptoms vary among people and over time. Often, symptoms include poor coordination, stiff muscles, weak muscles, and tremors. More...14 Oct 2020
Elevated Levels of Defective Mitochondrial DNA Predict Likelihood of Reproductive Success
A sperm biomarker has been found that may be able to supplement or replace the semen parameters that poorly predict reproductive success yet are the most prevalent diagnostic tool for male infertility. More...14 Oct 2020
Bacterium and Viral Coinfection Contributes to Postinfectious Hydrocephalus
Neonatal sepsis often precedes postinfectious hydrocephalus (PIH), although the manifestations of hydrocephalus typically emerge in the months after the neonatal period as sufficient cerebrospinal fluid (CSF) accumulates such that cranial expansion garners medical attention. More...12 Oct 2020
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In Other News
Elevated Levels of Lipoprotein(a) Predict Increased Risk for Developing Cardiovascular Diseases
Genome Sequencing Evaluated in Children with Unexplained Medical Complexity
Blood-Based Test Accurately Identifies Viral Infection Before Symptoms Develop
HPV, p16 Offers Different Prognostic Clues in Oropharyngeal Cancer
Bacteriophage Analysis Technique Reveals Details of COVID-19’s Impact on the Immune System
Large Genome-Wide Association Study Identifies Novel Abdominal Aortic Aneurysm Risk Loci
Smartphone Microscopic Method Detects Cryptosporidium and Giardia
Epigenetic Markers Predict Type 2 Diabetes Patients Response to Metformin
Endometrium Undergoes Gene Expression Shifts During Menstrual Cycle
Rapid One-Step Assay for Field-Based Detection of Asymptomatic Malaria
One-Step CRISPR-Based Assay Could Streamline COVID-19 Testing
Genomic Copy Number Predicts Esophageal Cancer Years Before Transformation
Paper-Based Microneedle Skin Patch for Continuous Glucose Monitoring
Circulating Tumor DNA Analysis Directs Therapy in Breast Cancer
A Paper-Based Nucleic Acid Testing Device for Rapid Diagnosis of Mosquito-Borne Viral Diseases
Click Chip’ Detects Early-Stage Liver Cancer Biomarkers in Extracellular Vesicles
Novel Rapid Lateral Flow Assay Measures Ovarian Cancer Biomarker CA125
Biosensing Platform Diagnoses Diseases Through Single Molecule Detection
Genetics Influence Risk for Spontaneous Coronary Artery Dissection
Proteomics-Based Diagnostic Test Predicts Risk of Dying from Staphylococcus aureus Bacteremia
Sequencing Could Augment Other Newborn Screening Methods
Jagged Ends of Double-Stranded DNA Characterized
MicroRNA-Based Liquid Biopsy Assay for Early Diagnosis of Head and Neck Cancer
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
