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Molecular Diagnostics

Image: Circulating tumor DNA (ctDNA) is found in serum and plasma fractions from blood. The mechanism of ctDNA release is unknown, though apoptosis, necrosis, and active secretion from tumor cells have been hypothesized. Once ctDNA is isolated, it can be sequenced for mutational analysis (Photo courtesy of Wikimedia Commons)

Highly Sensitive Liquid Biopsy Technique Brings Personalized Cancer Monitoring a Step Closer

A modified liquid biopsy method enables detection of circulating tumor DNA (ctDNA) with much greater sensitivity than previously used techniques and demonstrates the potential to revolutionize all aspects of cancer care, from early detection to personalized treatment and monitoring. More...
29 Jun 2020
Image: The MiSeq Next Generation Sequencer is an integrated instrument that performs clonal amplification, genomic DNA sequencing, and data analysis with base calling, alignment, variant calling, and reporting in a single run (Photo courtesy of Illumina).

Gut Microbiome Dysbiosis Characterized in Parkinson’s Disease

Parkinson’s disease (PD) is a common, progressive, and debilitating disease, which currently cannot be prevented or cured. With the exception of rare genetic forms, the cause of PD is unknown. Symptoms start gradually, sometimes starting with a barely noticeable tremor in just one hand. Tremors are common, but the disorder also commonly causes stiffness or slowing of movement. More...
29 Jun 2020
Image: The NanoDrop 2000 and 2000c are full-spectrum, UV-Vis spectrophotometers used to quantify and assess purity of DNA, RNA, Protein and more (Photo courtesy of Thermo Fisher Scientific).

Serum Mir‐22 Prognostic Marker Explored for Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is an aggressive hematopoietic stem cell malignancy that is characterized by the clonal proliferation of myeloid precursors. Abnormal accumulation of leukemic blasts in the bone marrow, blood, and other tissues results in significant reductions of normal blood cells. More...
25 Jun 2020
Image: Corbett Rotor-Gene 6000 Real Time PCR Machine (Photo courtesy of Corbett Life Science).

Isothermal Amplification Method Used to Detect Salmonella Subtypes

Salmonella is a common cause of foodborne disease worldwide, including Australia. More than 85% of outbreaks of human salmonellosis in Australia were caused by five Salmonella serovars. Rapid, accurate, and sensitive identification of Salmonella serovars is vital for diagnosis and public health surveillance. More...
25 Jun 2020
Image: Neuropathologic analysis of brain tissue from FTLD patients. Ubiquitin immunohistochemistry in cases of familial FTLD demonstrates staining of (a) neurites and neuronal cytoplasmic inclusions in the superficial cerebral neocortex, (b) neuronal cytoplasmic inclusions in hippocampal dentate granule cells, and (c) neuronal intranuclear inclusions in the cerebral neocortex (arrows). (Photo courtesy of Wikimedia Commons)

Serum Neurofilament Light Chain Is a Potential Prognostic Biomarker for Frontotemporal Lobar Degeneration

A recent study has confirmed previous results showing that the protein serum neurofilament light chain is a potential prognostic biomarker for frontotemporal lobar degeneration. More...
24 Jun 2020
Image: Micrograph of hepatocellular carcinoma (liver cancer) (Photo courtesy of Wikimedia Commons)

Diagnosing Liver Cancer by Screening Viral Exposure History

A blood test has been developed that enables diagnosis of hepatocellular carcinoma (HCC), the most common form of liver cancer by screening for an individual's previous exposure to certain viruses. More...
23 Jun 2020
Image: The multi-layer EV-CLUE chip device. The microreactors and connecting channels are visualized by filling with blue food dye. The bottom glass slide is patterned with nanoparticle structures and coated with antibody to capture extracellular vesicles (Photo courtesy of Dr. Yong Zeng)

A Novel Liquid Biopsy Device Enables Early Cancer Detection and Diagnosis

A novel liquid biopsy device for early cancer detection and diagnosis was used to isolate and analyze extracellular vesicles from breast cancer tumors. More...
22 Jun 2020
New
Gold Member
Collection and Transport System
PurSafe Plus®
Portable Electronic Pipette
Mini 96
New
Capillary Blood Collection Tube
IMPROMINI M3
Silver Member
Rapid Test Reader
DIA5000


Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.