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Recent News Expo Medica 2025 Clinical Chem. Molecular Diagnostics Hematology Immunology Microbiology Pathology Technology Industry Focus

Molecular Diagnostics

Image: The portable MinION sequencing platform runs one flow cell and desktop GridION can run up to five flow cells at any time (Photo courtesy of Oxford Nanopore).

Metagenomic Sequencing Quickly Identifies Pathogens in Body Fluids

Metagenomic next-generation sequencing (mNGS) is a shotgun sequencing approach in which all of the nucleic acid (DNA and RNA) in a clinical sample is sequenced at a very high depth, 10-20 million sequences per sample. More...
23 Nov 2020
Image: A clot in the neck or brain can lead to a stroke (Photo courtesy of Mayo Clinic)

Blood Biomarker Protein Correlates with Severity of Brain Damage in Stroke Patients

Researchers have identified a stroke-related biomarker protein that correlates with the severity of brain tissue damage as well as with functional outcome and mortality. More...
23 Nov 2020
Image: Histological features of COVID-19 lungs (Photo courtesy of the University of Trieste).

COVID-19 Lung Damage Caused by Persistence of Abnormal Cells

Several uncertainties still relate to the involvement of other organs in COVID-19. Besides indirect multi-organ injury, a few reports have suggested the possibility of direct injury caused by viral replication in brain, heart and kidney. More...
19 Nov 2020

Levels of MicroRNAs in Saliva Are Diagnostic for Mild Traumatic Brain Injury

Measurement of levels of microRNAs in saliva was used to diagnose the presence of concussion (mild traumatic brain injury or mTBI) in a group of patients suffering from head trauma. More...
17 Nov 2020
Image: Schematic diagram of cell-free methylated DNA immunoprecipitation and high-throughput sequencing (cfMeDIP-seq) (Photo courtesy of Princess Margaret Cancer Centre).

Methylated DNA Profiling Explored for Prenatal Testing Applications

A method for analyzing cell-free methylated DNA being developed for use in cancer liquid biopsy testing can potentially also be used for prenatal testing applications. More...
17 Nov 2020
Image: Model of C-reactive protein (CRP) (Photo courtesy of Wikimedia Commons)

CRP Tracking Predicts Potential Outcome for Hospitalized COVID-19 Patients

By tracking the increase in circulating levels of the inflammatory biomarker C-reactive protein, doctors are able to predict whether newly hospitalized COVID-19 patients will suffer respiratory deterioration with the possible need for intubation. More...
16 Nov 2020
Image: Vacuolated erythroid precursors in the bone marrow are sometimes found in patients with severe adult-onset autoinflammatory disorder (Photo courtesy of Teresa S. Scordino, MD).

Blood Cell Mutations Underlie Severe Autoinflammatory Disease

Severe adult-onset autoinflammatory disorders often manifest with overlapping clinical features. Affected individuals may develop episodes of high, spiking fevers, a pink or salmon colored rash, joint pain, muscle pain, a sore throat and other symptoms associated with systemic inflammatory disease. More...
12 Nov 2020
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