Molecular Diagnostics
Next-Gen Sequencing Matches Blood Group Antigens for Transfusion
Transfusion is the procedure of introducing donor material with unknown blood cell antigens into the recipient’s circulatory system. The recipient’s immune system recognizes foreign antigens, produces specific antibodies and sensitization (alloimmunization) occurs. More...26 Sep 2019
Distinctive mRNA Signatures May Prove Diagnostic for Cancer-Related AIS
A recently published paper described a distinctive molecular signature present in blood mRNA expression profiles of patients with cancer-related acute ischemic stroke (AIS) that could potentially lead to earlier diagnosis of cancer in these patients. More...22 Sep 2019
Multiplex Microsphere Immunoassay Identifies Three Flavivirus Infections
The explosive spread of Zika virus (ZIKV) and associated complications in flavivirus-endemic regions underscore the need for sensitive and specific serodiagnostic tests to distinguish ZIKV, dengue virus (DENV) and other flavivirus infections. More...19 Sep 2019
Pathogenic Germline Variants Found in Breast Cancer Patients
There is still considerable debate on the value of multigene panel testing for inherited cancer in patients with breast cancer, based on both the prevalence of pathogenic/likely pathogenic (P/LP) variants and any therapeutic implications from genetic test results. More...18 Sep 2019
Biomarker Identified for Early Beta-Cell Death in Type 1 Diabetes
Beta cells in the pancreas produce insulin and their death is a key feature of Type 1 diabetes, and that loss starts long before diagnosis. However, there has been no straightforward way to measure that early loss. More...18 Sep 2019
Automated Collection of CTCs Improves Prostate Cancer Diagnosis
A recent paper described the benefits of circulating tumor cell (CTC) analysis for improving the diagnosis of aggressive prostate cancer beyond currently used PSA (prostate specific antigen) measurement, biopsy and/or MRI imagery. More...16 Sep 2019
In Other News
Zika Virus Test Kit Receives American Marketing Approval
Autoimmune Antibody Identified as Biomarker for Tachycardia Syndrome
Human Intestinal Enteroids Used to Detect Norovirus Infectivity
Detergent-Enhanced LAMP Detects African Trypanosome in CSF
Fungus-Associated Bacteriome Associated with C. difficile Infection
Novel Cell‐Free DNA Screening Assay Validated for Trisomies
Methylated MicroRNAs Prove Biomarkers for Early Detection of Cancer
New Official Guideline Summarizes Advances in Fungal Infections Diagnosis
Metabolites Pattern Distinguishes Myasthenia Gravis from RA Patients
Genetics Affect Risk of Developing Factor VIII Inhibitors
Type 1 Diabetes Risk Reflected in Gut Microbiome
Persistent C-Peptide Secretion in Type 1 Diabetes Genetic-Related
Sequencing Methods for Hepatitis C Virus Genotyping Compared
Concussive Injuries Diagnosed by Measuring a Brain Protein in Blood
Protein Biomarker Panel Enables Early Detection of Cancer
Biomarker Panel Accurately Predicts Mortality Risk
C. Difficile Bacteria Adapted to Spread in Hospitals
Enterovirus Antibodies Detected in Acute Flaccid Myelitis Patients
Signature for Beta-Cell Autoimmunity Predicts Type 1 Diabetes
Mutations Linked to Familial Pancreatic Cancer Identified
Potential Biomarkers Found in Glioblastoma Small Extracellular Vesicles
Specialized White Blood Cells Prove Biomarkers for Diabetes Progression
Study Supports Body Area Sensory Networks for Diagnostic Monitoring
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.