Molecular Diagnostics
Leukocyte Epigenomics and Artificial Intelligence Predict Late-Onset Alzheimer’s Disease
Alzheimer’s Disease (AD) is the most common form of age-related dementia, accounting for 60%–80% of such cases. The disorder causes a wide range of significant mental and physical disabilities, with profound behavioral changes and progressive impairment of social skills. More...12 Apr 2021
Genome Sequencing Identifies Myeloma Precursor Disease with Progression Risk
Multiple myeloma (MM) is the second most common hematological malignancy and is consistently preceded by the asymptomatic expansion of clonal plasma cells, termed either monoclonal gammopathy of undetermined significance (MGUS) or smoldering myeloma (SMM). More...08 Apr 2021
Single-Cell Transcriptomic Analysis Traces Neuroblastomas to Developing Adrenal Neuroblasts
Neuroblastoma is the most common cancer in infants and the third-most common cancer in children after leukemia and brain cancer. Approximately one in every 7,000 children is affected at some time and about 90% of cases occur in children less than five years old, and it is rare in adults. More...07 Apr 2021
Salivary Diagnostic Signatures of Concussion Found in Male Athletes
Sport-related concussion is defined as a traumatic brain injury induced by biomechanical forces that typically results in the rapid onset of short-lived impairment of neurological function that resolves spontaneously. A high percentage of cases may go misdiagnosed or unidentified. More...05 Apr 2021
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In Other News
Whole-Genome Sequencing Aids Rare Disease Diagnosis
Lupus Genetic Risk Variant Allelic Enhancer Activity Discovered
PCR Method Identifies Microsatellite Instability in Tumor-Derived Samples
Disease Diagnosis Based on Infrared Analysis of Blood Samples
A High-Throughput Single Telomere Length Analysis Approach for Diagnosis of Telomeopathic Diseases
Genome Sequencing More Informative than Cytogenetic Analysis in Myeloid Cancers
Genetic Mutations Identified for Rare VEXAS Syndrome
Immune Cells in Cerebrospinal Fluid Predict Response to Immunotherapy
A Rapid, Non-Invasive Skin Test for Diagnosis of Parkinson’s Disease
Pediatric Pancreatic Cancer Diagnosed from cfDNA Fragments in Urine
Clonal Hematopoiesis and Recurrent Mutations Identified in Blood Cancers
Liquid Biopsy Technique Detects Circulating Tumor Cells in Patients with Non-Small Cell Lung Cancer
Analysis of Urinary Exosome RNA Can Diagnose Kidney Transplant Rejection
Whipple’s Disease Pathogen Found in International Diarrhea Patients
Five Genes Help Predict Lewy Body Dementia
Low Lymphocyte Counts Linked to More Severe Sarcoidosis Inflammation
Childrens’ Urinary MicroRNAs Predict Future Development of Heart or Kidney Diseases
Clinical Germline Testing Evaluated for Pediatric Cancer Patients
Genetic Risk of Inflammatory Bowel Disease Appears Distinct in African Americans
ctDNA Provides Prognostic Clues in Advanced BRAF-Mutated Melanoma Cases
Rapid Lateral Flow Assays Detect COVID-19 Variants and Differentiate COVID-19 from Other Respiratory Viral Diseases
Elevated Plasma Levels of Glial Fibrillary Acidic Protein Indicate Increased Alzheimer’s Risk
Pulse-Controlled Amplification Tested for Infectious Disease Diagnostics
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.