Molecular Diagnostics
The OncoMasTR Test Accurately Identifies Risk of Breast Cancer Recurrence
A recent paper confirmed that the Oncomark (Dublin, Ireland) OncoMasTR test can accurately identify the risk for disease recurrence in patients with hormone receptor–positive HER2-negative early-stage breast cancer. More...29 Jun 2021
Highly Sensitive Molecular Test Detects Cases of Tuberculosis
Tuberculosis (TB) is a bacterial infection spread through inhaling tiny droplets from the coughs or sneezes of an infected person. It mainly affects the lungs, but it can affect any part of the body, including the tummy (abdomen), glands, bones and nervous system. More...28 Jun 2021
Serum Thrombospondin 2 Identified as Biomarker for Patients at Risk of Nonalcoholic Fatty Liver Disease
Serum levels of the glycoprotein thrombospondin 2 (TSP-2) were shown to be a useful biomarker for non-alcoholic steatohepatitis (NASH) and advanced fibrosis diagnosis in nonalcoholic fatty liver disease (NAFLD) patients. More...28 Jun 2021
Genetic Variants Associated with Unexplained Sudden Cardiac Death
As many as 450,000 Americans die every year from a sudden, fatal heart condition, and in slightly more than one in ten cases the cause remains unexplained even after an autopsy. Most sudden cardiac deaths are caused by abnormal heart rhythms called arrhythmias and the most common life-threatening arrhythmia is ventricular fibrillation. More...22 Jun 2021
CtDNA Analysis Assesses Early Relapse Detection in Colorectal Cancer
Colorectal cancer (CRC) is a type of cancer that begins in the large intestine (colon). The colon is the final part of the digestive tract. Colon cancer typically affects older adults, though it can happen at any age. It usually begins as small, noncancerous (benign) clumps of cells called polyps that form on the inside of the colon. Over time some of these polyps can become colon cancers. More...17 Jun 2021
Liquid Biopsies Detect Pediatric Bone Tumors Based on Epigenetic Profiles
Sequencing of cell-free DNA (cfDNA) in the blood of cancer patients (liquid biopsy) provides attractive opportunities for early diagnosis, assessment of treatment response, and minimally invasive disease monitoring. As a consequence, cfDNA analysis holds great promise for precision oncology and personalized therapies, and is currently evaluated in a broad range of clinical studies. More...17 Jun 2021
Genomic Differences Cause Racial Disparities in Prostate Cancer
Prostate cancer is a disease defined by the abnormal growth of cells. These abnormal cells can proliferate in an uncontrolled way and, if left untreated, form tumors which may metastasize or spread to other parts of the body. Prostate cancer (PCa) is the most common solid organ malignancy in men, with 174,650 new diagnoses and 31,620 deaths expected in 2019 in the USA alone. More...17 Jun 2021
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In Other News
Plasma Levels of Neurofilament Light Chain Protein Accurately Identify Neurodegenerative Disease Patients
A Mucin Protein Is a New Prognostic Biomarker for Chronic Obstructive Pulmonary Disease
Low-Cost Transcriptional Diagnostic Accurately Categorizes Lymphomas
Circulating Tumor DNA Following Surgery Predicts Colorectal Cancer Recurrence
Familial Hypercholesterolemia Tends to Slip Past Genetic Tests
Personalized CtDNA Analysis Detects Minimal Residual Disease
Blood MicroRNA Biomarker Distinguishes Myocarditis from Myocardial Infarction
A Novel Liquid Biopsy Technique for Diagnosis of Cancers in Children
Analytic Validation and Clinical Utilization of Comprehensive Genomic Profiling Test
Colorectal Cancer Relapse Predicted by ctDNA Clearance
Urinary Interleukin-8 May Be the Ultimate Bladder Cancer Biomarker
Plasma-Based Algorithm Accurately Predicts Likelihood of Developing Alzheimer’s Disease
Jagged Ends of Urinary Cell-Free DNA Assessed in Bladder Cancer Detection
Early Warning Biomarker Proteins Appear Years or Decades Before Alzheimer’s Disease Symptoms
Non‐Invasive Urine Markers Differentiate Renal Cancer from Oncocytoma
Measurement of Oxidized Serum Albumin for Diagnosis of Diabetic Kidney Disease
Jagged Ends of Urinary Cell-Free DNA Assessed in Bladder Cancer Detection
Rapid, Automated Test Detects Gonorrhea and Determines Antibiotic Susceptibility
Loss of Function Mutations in GEMIN5 Causes Neurodevelopmental Disorder
Elevated Cytokine Levels Linked to Future Development of Myocardial Infarction
New Blood Test Promises Biopsy-Free Colon Cancer Diagnosis
A Novel Capsule-Based Smell Test for Diagnosis of Neurological and Respiratory Diseases
Genetic Background and Clinicopathologic Features Established for Adult-Onset Nephronophthisis
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
