Molecular Diagnostics
Optical Genome Mapping Enables Constitutional Chromosomal Aberration Detection
Optical genome mapping (OGM) is a novel method that fills this void by being able to detect all classes of structural variations (SVs), including copy number variations (CNVs). OGM is being adopted by laboratories as a tool for both postnatal constitutional genetic disorders and hematological malignancies. More...20 Jul 2021
Serum Biomarkers Enable Tracing the Progress of COVID-19 Infections
A team of Spanish investigators has shown that levels of angiotensin-converting enzyme 2 and various truncated versions of this protein in the blood could be used as biomarkers for following the progress of COVID-19 infection in hospitalized patients. More...20 Jul 2021
Rectal Colonization by Klebsiella Leads to Different Risks for Bacteremia
Carbapenem-resistant Enterobacterales (CRE) represent a threat for public health, being among the top multidrug-resistant pathogens. Intestinal colonization by CRE is a risk factor for developing subsequent infection. More...20 Jul 2021
Telomerase Reverse Transcriptase Protein Expression Evaluated for Melanomas
Telomeres are regions of repetitive nucleotide sequences located at the ends of chromosomes that play a key role in the maintenance of genomic integrity and stability in cells. In normal nonneoplastic somatic cells, telomeres progressively shorten with successive cell divisions. More...19 Jul 2021
Metabolomic Analytical Approach Identifies Multiple Neonatal Errors of Metabolism Disorders
A recent paper demonstrated that an untargeted metabolomics analytical approach could identify many more neonatal disorders caused by inborn errors of metabolism (IEM) than could be found by traditional methods. More...19 Jul 2021
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In Other News
Rotavirus Co-Infection with Diarrheagenic Pathogens Detected by Different Methods
Portable, PCR-Based Assay Developed for Rapid, Multiplexed DNA Detection
Genotyping Helps Avoid Needless Bone Marrow Biopsies in African-Americans
A Novel Nanowell Array Sensor for POC Measurement of Stress Hormones
Novel Stool Biomarker Screening Tests Detect Colorectal Cancer and Inflammatory Bowel Disease
Protein Biomarker Blood Test Accurately Detects Alzheimer’s Disease
Sensitive PCR Test Predicts Treatment Response in Metastatic Head and Neck Cancers
Blood-based Liquid Biopsy Test Accurately Detects More Than Fifty Types of Cancer
Circulating Tumor DNA Following Surgery Predicts Bladder Cancer Recurrence
A Nanowire-based Liquid Biopsy Method for Detection of Tumors of the Central Nervous System
The OncoMasTR Test Accurately Identifies Risk of Breast Cancer Recurrence
Highly Sensitive Molecular Test Detects Cases of Tuberculosis
Serum Thrombospondin 2 Identified as Biomarker for Patients at Risk of Nonalcoholic Fatty Liver Disease
Genetic Variants Associated with Unexplained Sudden Cardiac Death
CtDNA Analysis Assesses Early Relapse Detection in Colorectal Cancer
Liquid Biopsies Detect Pediatric Bone Tumors Based on Epigenetic Profiles
Genomic Differences Cause Racial Disparities in Prostate Cancer
Plasma Levels of Neurofilament Light Chain Protein Accurately Identify Neurodegenerative Disease Patients
A Mucin Protein Is a New Prognostic Biomarker for Chronic Obstructive Pulmonary Disease
Low-Cost Transcriptional Diagnostic Accurately Categorizes Lymphomas
Circulating Tumor DNA Following Surgery Predicts Colorectal Cancer Recurrence
Familial Hypercholesterolemia Tends to Slip Past Genetic Tests
Personalized CtDNA Analysis Detects Minimal Residual Disease
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
