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Molecular Diagnostics

Image: Histopathology of Alzheimer\'s disease in the CA3 area of the hippocampus: Amyloid plaque (top right), neurofibrillary tangles (bottom left) and granulovacuolar degeneration (bottom center). All three images were taken at the same high magnification (Photo courtesy of Wikimedia Commons)

Early Warning Biomarker Proteins Appear Years or Decades Before Alzheimer’s Disease Symptoms

A large proteomic study linked abnormal blood levels of 38 proteins to higher risks of developing Alzheimer's disease within five years and showed that levels of 16 of these proteins could predict Alzheimer's disease risk two decades in advance. More...
26 May 2021
Image: The CHEMOSTAR Touch ECL & Fluorescence Imager (Photo courtesy of INTAS)

Non‐Invasive Urine Markers Differentiate Renal Cancer from Oncocytoma

Clear cell renal cell carcinoma, (ccRCC), is a type of kidney cancer. Clear cell renal cell carcinoma is also called conventional renal cell carcinoma. Clear cell renal cell carcinoma is named after how the tumor looks under the microscope. More...
25 May 2021
Image: The structure of human serum albumin (HSA) complexed with six palmitic acid molecules (Photo courtesy of Wikimedia Commons)

Measurement of Oxidized Serum Albumin for Diagnosis of Diabetic Kidney Disease

A recent paper reported that oxidized (cysteinylated) albumin in serum can be used as an early diagnostic marker for diabetic kidney disease. More...
25 May 2021
Image: Schematic of workflow for urinary DNA jagged end analysis. Urinary DNA was subjected to an end-repair process; JI-U = jagged index–unmethylated (Photo courtesy of The Chinese University of Hong Kong)

Jagged Ends of Urinary Cell-Free DNA Assessed in Bladder Cancer Detection

Bladder cancer is where a growth of abnormal tissue, known as a tumor, develops in the bladder lining. In some cases, the tumor spreads into the bladder muscle. The most common symptom of bladder cancer is blood in the urine, which is usually painless. More...
24 May 2021
Image: Dr. Tza-Huei Wang displays the PROMPT test cartridge for rapid diagnosis of gonorrhea infection (Photo courtesy of Johns Hopkins University)

Rapid, Automated Test Detects Gonorrhea and Determines Antibiotic Susceptibility

An inexpensive, portable diagnostic test that gives results in only 15 minutes is expected to revolutionize detection of sexually transmitted diseases such as gonorrhea. More...
24 May 2021
Image: Diagrammatic representation showing the possible mode of disruption in small nuclear ribonucleoproteins (snRNP) complex formation due to loss of GEMIN5 in L1068P and H913R variants

Loss of Function Mutations in GEMIN5 Causes Neurodevelopmental Disorder

GEMIN5, an RNA-binding protein is essential for assembly of the survival motor neuron (SMN) protein complex and facilitates the formation of small nuclear ribonucleoproteins (snRNPs), the building blocks of spliceosomes. More...
20 May 2021
Image: Crystal structure of IL-6 (Photo courtesy of Wikimedia Commons)

Elevated Cytokine Levels Linked to Future Development of Myocardial Infarction

Elevated levels of the plasma biomarkers interleukin-6 (IL-6) and the IL-6 binary complex have been linked to the increased risk of myocardial infarction (MI) found in smokers and individuals with hypertension. More...
17 May 2021
New
Gold Member
Collection and Transport System
PurSafe Plus®
Portable Electronic Pipette
Mini 96
New
ESR Analyzer
TEST1 2.0
New
Gold Member
Automatic Hematology Analyzer
DH-800 Series


Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.