Molecular Diagnostics
World’s First Rapid Oral Cancer Test to Revolutionize Diagnosis and Treatment
Researchers at Queen Mary University of London (London, UK) have developed the world’s first PCR test for mouth cancer that may improve the early detection of oral cancer. The test is quick and easy. It only needs the PCR machine used in COVID testing and a technician to operate it. It could be rapidly rolled out around the world at very little extra cost. More...14 Apr 2022
Broad Gene Panel Diagnoses Patients With Kidney Disease
Chronic kidney disease (CKD) is a major public health issue in the USA. Identification of monogenic causes of CKD, which are present in ∼10% of adult cases, can impact prognosis and patient management. For the ∼800,000 individuals in the USA with end-stage kidney disease (ESKD), genetic diagnosis may inform the selection of potential-related kidney donors, assess the risk of disease recurrence, and guide clinical management following transplant. More...13 Apr 2022
Single-Cell RNA-Seq Reveals Cell Type–Specific Molecular and Genetic Associations to Lupus
Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease with elevated prevalence in women and individuals of Asian, African, and Hispanic ancestry. SLE is a disease in which the immune system attacks its own tissues, causing widespread inflammation and tissue damage in the affected organs. It can affect the joints, skin, brain, lungs, kidneys, and blood vessels. More...12 Apr 2022
Lyo-Ready PCR Reagents Make Ultra-Sensitive Diagnostics Development Painless
PCR Biosystems Ltd. (London, UK) has launched the Lyo-Ready Probe 1-Step Kit, a lyophilizable 4x RT-qPCR reagent mix designed for ultra-sensitive high-throughput detection of RNA sequences. The new reagents will bring the exceptional sensitivity of the company’s liquid format 1-step RT-qPCR reagents to a freeze-dryable format. More...12 Apr 2022
Smartphone-Powered Microfluidic ‘Lab on a Strip’ Dengue Test More Powerful Than LFT Testing
Dengue fever affects an estimated 400 million people each year and dengue is a serious health challenge facing half the global population. Now, new ‘lab on a strip’ technology has shown the capability of smartphone-powered tests for dengue fever. More...11 Apr 2022
Single-Cell RNA Sequencing Identifies Mechanisms Underlying Autoimmune Diseases
Two recently published studies were designed to help understand how gene expression patterns are cell-type and context specific and can explain observed variation in immune cell function among individuals. More...11 Apr 2022
Cervicovaginal DNA Virome Alterations Associated with Genital Inflammation
Cervical cancer is one of the most common cancers among women. In 2021, more than 600,000 cases and 340,000 deaths were reported worldwide. In addition to infection with the human papillomavirus (HPV), known risk factors for cervical cancer include immunodeficiency, smoking and oral contraceptive use. More...08 Apr 2022
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In Other News
High-Throughput Screening Assay Identifies Drugs to Treat Resistant Prostate Cancer
Circulating Levels of Anti-Müllerian Hormone Can Identify Premenopausal Women Prior to Significant Bone Density Loss
POC Sepsis Diagnostic Platform to Speed up Clinical and Treatment Decision Making
AI-Powered Voice-Activated Pipettes Streamline Processes and Increase Lab Productivity
Liquid Biopsy Enables Early Cancer Detection in Li-Fraumeni Syndrome Patients
World-First Bedside Genetic Test Identifies Susceptibility to Deafness in Newborn Babies
World-First Bedside Genetic Test Identifies Susceptibility to Deafness in Newborn Babies
Blood Test to Detect Protein Biomarkers Identified Using Breast Milk Could Enable Breast Cancer Screening
Newly Identified Biomarkers Detect Subcortical Small-vessel Disease
miRNA-Based Blood Borne Diagnostic Test Holds Potential for Management of Cancer Patients
Liquid Biopsy Can Detect Recurrent Breast Cancer and Monitor Progression
Thermo Fisher Launches CE-IVD Marked NGS Instrument for Diagnostic Testing
Siemens sNfL Blood Test Predicts Risk of MS Disease Activity
Rapid Test Predicts Sepsis Soon After Infection and Before Organ Damage
NGS Panels Detect RNA and DNA Cancer Biomarkers in Single Assay
Novel System to Accelerate Development of New Diagnostic Tests
Urine Liquid Biopsy Test Detects Molecular Evidence of Prostate Cancer
BDNF Risk Variant Linked to Brain Inflammation in RRMS Patients
Blood Levels of Glial Fibrillary Acidic Protein Predict Dementia Risk in Older Mexican Americans
A Minimally Invasive PCR Test for Diagnosis of Oral Cancer
Enzyme-Based Point-of-Care Test Could Rapidly Identify Stroke Patients upon Arrival at Hospital
New Antibody Test Diagnoses Multiple Sclerosis in 20 Minutes
An Extracellular Vesicle-based Liquid Biopsy for Early Cancer Detection
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.