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Molecular Diagnostics

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Cheek Swab Test Could Identify Biomarkers for Rheumatoid Arthritis

Cells from a cheek swab revealed biomarkers for rheumatoid arthritis that could lead to a way to diagnose and begin treatment before the disease develops, according to a new study. More...
14 Dec 2021
Image: Electron micrograph of human papilloma virus (HPV) (Photo courtesy of [U.S.] National Institutes of Health via Wikimedia Commons)

Rapid Biopsy Approach Shortens Time Required to Diagnose HPV-linked Head and Neck Cancers

A non-invasive, liquid biopsy approach for the diagnosis of head and neck squamous cell carcinomas caused by human papilloma virus (HPV+HNSCC) demonstrated improved accuracy, reduced cost, and a shorter time to diagnosis compared to the current clinical workup and could become the method of choice in the future. More...
13 Dec 2021
Image: The TruSight RNA Fusion Panel kit provides comprehensive gene fusion detection in formalin-fixed, paraffin-embedded (FFPE) and other cancer samples (Photo courtesy of Illumina)

Targeted RNA-Sequencing Panel Detects Gene Fusions in Solid Tumors

Increasingly, rearrangements resulting in gene fusions have been revealed in multiple tumor types across diverse organ systems. These gene fusions can drive tumorigenesis by altering gene expression and activity. Timely and reliable detection of fusions provides useful information to the pathologist and clinical team. More...
07 Dec 2021
Image: Lateral flow detection of hepatitis C virus (HCV) using a novel LAMP assay (Photo courtesy of Nature Communications at www.nature.com)

A Device for Rapid and Accurate Diagnosis of Hepatitis C Infections

A device has been developed that enables the rapid and accurate diagnosis of hepatitis C infections under both laboratory and field conditions. More...
07 Dec 2021
Image: Model of the PD-1 (Programmed cell death protein 1) protein. Only a subset of recurrent glioblastomas respond to anti-PD-1 immunotherapy (Photo courtesy of Wikimedia Commons)

Biomarker Predicts Potential Benefit of Checkpoint Inhibitor Therapy for Brain Cancer Patients

A phosphorylated form of ERK (extracellular signal-regulated kinase) protein has been identified as a biomarker that may be used to predict which brain cancer patients might benefit from checkpoint inhibitor therapy. More...
06 Dec 2021
Image: Clinical metagenomics (CMg) using nanopore sequencing (Photo courtesy of Oxford Nanopore Technologies)

Same Day Test Identifies Secondary Infections in COVID-19 Patients

The intensive care unit (ICU) is a dynamic environment with frequent staff-patient contact for invasive monitoring, interventions and personal care that together introduce the risk of secondary or nosocomial infection. When critically ill patients are cared for in the ICU, doctors may take deep samples from their lungs. More...
02 Dec 2021
Image: Schistosoma haematobium, the most common cause of urogenital schistosomiasis in humans (Photo courtesy of Romy Bullerjahn)

A Rapid and Sensitive Lateral Flow Test for Diagnosis of Schistosomiasis

A novel lateral flow immunoassay enables the rapid and sensitive diagnosis of the urogenital form of schistosomiasis in both laboratory and field settings. More...
01 Dec 2021
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.