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Molecular Diagnostics

Image: Schematic of melanoma (skin cancer) (Photo courtesy of 123rf.com)

Novel Biomarkers Predict Response of Melanoma Patients to Immunotherapy

A recent paper described a way to use blood bioenergetics and metabolomics as predictive biomarkers to determine melanoma patients’ response to immune checkpoint inhibitor therapy. More...
28 Feb 2022
Image: Schematic Diagram of Whole-Genome Sequencing that was used to diagnose neurological repeat expansion disorders (Photo courtesy of Centers of Disease Control and Prevention)

Whole-Genome Sequencing Diagnoses Neurological Repeat Expansion Disorders

Scientists have found whole genome sequencing (WGS) can quickly and accurately detect the most common inherited neurological disorders – something previously thought to be impossible – with the results supporting the use of WGS as a standard diagnostic tool within routine clinical practice. More...
25 Feb 2022
Image: Bone marrow of a pediatric patient with acute myeloid leukemia (Photo courtesy of St. Jude Children’s Research Hospital)

High-Risk Subtype of Relapsed Pediatric Acute Myeloid Leukemia Revealed

Scientists have found a previously overlooked mutation in a subtype of pediatric leukemia that has implications for identifying high-risk patients. More...
25 Feb 2022
Image: Representation of the structure of C-reactive protein (CRP) (Photo courtesy of Wikimedia Commons)

C-reactive Protein Level Can Replace Erythrocyte Sedimentation Rate for Defining the Severity of Ulcerative Colitis

A research team in Australia has determined that a blood level of C-reactive protein equal to or greater than 12 milligrams/liter is a practical alternative to measurement of ESR (Erythrocyte Sedimentation Rate) for defining the severity of ulcerative colitis. More...
24 Feb 2022
Image: Genome Sequencing Reveals Fetal Structural Anomalies (Photo courtesy of National Human Genome Research Institute)

Genome Sequencing Investigated for Prenatal Diagnosis of Fetal Structural Anomalies

Whole-genome sequencing is a promising alternative to currently used assays to diagnose fetal anomalies, a new analysis has found. More...
24 Feb 2022
Image: Photomicrograph of a poor to moderately differentiated adenocarcinoma of the stomach (Photo courtesy of Wikimedia Commons)

Genetic Signature Predicts Patients’ Response to Gastric Cancer Therapy

A 32-gene signature was developed and shown to be a promising prognostic and predictive biomarker to guide the clinical care of gastric cancer patients. More...
22 Feb 2022
Image: LumiraDx CRP Test (Photo courtesy of LumiraDx)

LumiraDx C-Reactive Protein (CRP) Test Achieves CE Marking

LumiraDx (London, UK) has achieved CE Marking for its C-reactive protein (CRP) Test, a small, portable, fully automated, microfluidic immunoassay test used for the quantitative determination of C-reactive protein with results within four minutes. More...
21 Feb 2022
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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