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Molecular Diagnostics

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Meridian Launches New Air-Dryable qPCR Mix Enabling Direct Detection of RNA from Whole Blood Samples

Meridian Bioscience, Inc. (Cincinnati, OH, USA) has launched its new Air-Dryable Direct RNA/DNA qPCR Blood Mix, an innovative master mix designed to develop room-temperature stable molecular diagnostic assays that directly amplify RNA from crude whole blood, serum, or plasma. More...
08 Oct 2021
Image: The SureSelect Target Enrichment System is a highly efficient hybrid selection technique for optimizing next-generation sequencing (Photo courtesy of Agilent Technologies)

ALPK3 Truncating Variants Cause Autosomal Dominant Hypertrophic Cardiomyopathy

In hypertrophic cardiomyopathy, heart muscles are thicker, which can make it harder for the heart to receive and pump blood. While in most cases the condition will not affect daily life, it can cause heart failure and is frequently cited as the most common cause of sudden unexpected death in young people. More...
07 Oct 2021
Image: The QIAcube is an automated system which can extract DNA or RNA from up to 12 samples simultaneously (Photo courtesy of Qiagen)

PCR Assay Detects and Differentiates Coccidioides Species

Coccidioidomycosis (Valley Fever) is a pulmonary and systemic fungal disease with increasing incidence and expanding endemic areas. The differentiation of etiologic agents Coccidioides immitis and C. posadasii remains problematic in the clinical laboratories as conventional PCR and satellite typing schemes are difficult. More...
07 Oct 2021
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Next-Generation Multiomics Blood-Based Test for Pancreatic Cancer Could Become Powerful Tool for Early Diagnosis and Treatment

Freenome Holdings, Inc. (South San Francisco, CA, USA) has demonstrated the potential of extending its multiomics approach into other cancers, such as pancreatic cancer, with biomarkers already embedded in the existing platform. More...
07 Oct 2021
Image: Circulating tumor DNA (ctDNA) is found in the bloodstream and refers to DNA that comes from cancerous cells and tumors. The LiquidHALLMARK assay, a liquid biopsy test, tracks treatment-based ctDNA changes (Photo courtesy of Jonathan Bailey, National Human Genome Research Institute)

Liquid Biopsy Test Tracks Treatment-Based ctDNA Changes

Metastatic or unresectable disease is identified in approximately 20% of patients presenting with invasive urothelial cancer. In addition, up to 50% of patients will develop metastases following radical cystectomy for clinically localized disease. More...
06 Oct 2021
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New State-of-the-Art, Ultrasensitive Blood Test to Transform Detection of Brain Damage and Poor Prognosis After Head Injury

A new study has used a state-of-the-art blood test to track damage to the brain in people who have sustained traumatic brain injury (TBI). More...
06 Oct 2021
Image: The DELFI blood test identifies lung cancer using artificial intelligence to detect unique patterns in the fragmentation of DNA shed from cancer cells compared to normal profiles (Photo courtesy of Carolyn Hruban)

A Blood-Based Liquid Biopsy Combined with Machine Learning for Early Lung Cancer Diagnosis

A novel liquid biopsy that collects fragments of circulating tumor DNA combined with advanced machine learning technology was able to detect over 90% of lung cancers in samples from nearly 800 individuals with and without the disease. More...
05 Oct 2021
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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