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Molecular Diagnostics

Image: New test could potentially diagnose Lyme disease (Photo courtesy of Unsplash)

New Test Could Help Diagnose Lyme Disease Sooner and Determine Treatment Efficacy

Traditional tests for Lyme disease, caused by a bite from an infected tick, can stay positive for prolonged periods of time after treatment, making it difficult for clinicians to diagnose persistent Lyme disease cases. Now, researchers have identified just such a testing mechanism that detects a type of antibody that infected individuals produce against a substance the Lyme bacteria acquires from the host in order to grow. More...
16 Mar 2022
Image: NovaSeq 6000 offers deeper and broader coverage through advanced applications for a comprehensive view of the genome (Photo courtesy of Illumina)

Expression, Microbiome Features Provide Pre-Treatment Lung Function Clues for Pediatric Patients

Microbial community and host gene expression features in lung samples may provide pre-treatment clues to risky lung function features in children receiving bone marrow transplants from healthy donor individuals, new research suggests. More...
15 Mar 2022
Image: Next generation graphene biosensors to enable lab quality diagnostics (Photo courtesy of Unsplash)

Next-Gen Graphene Biosensor Technology Enables Lab Quality Diagnostics of Infectious Diseases, Anytime, Anywhere

A new novel graphene-based electronic biosensor technology under development aims to provide rapid, simultaneous, lab-grade accuracy detection of an array of infectious diseases, anytime, anywhere, by any user. More...
14 Mar 2022
Image: Illustration of carotid atherosclerosis (Photo courtesy of Wikimedia Commons)

Two Circulating Biomarkers Predict Cardiovascular Disease Risk in Psoriasis Patients

Blood levels of the protein biomarkers cardiac troponin I (cTnI) and N-terminal pro-brain-type natriuretic peptide (NT-proBNP) in patients with psoriatic disease (PsD) were found to be associated with carotid plaque burden and the development of cardiovascular disease (CVD) independent of traditional CVD risk factors. More...
11 Mar 2022
Image: In red, Bacteroides, one of the microorganisms identified in this work, inside nucleus of a pancreatic cell, in blue (Photo courtesy of CNIO)

Fecal Microbiome Signature Predicts Pancreatic Cancer Risk

Researchers have identified a molecular signature of 27 microorganisms in stool samples that is able to predict whether an individual is at high risk of developing pancreatic ductal adenocarcinoma, the most common form of pancreatic cancer. More...
10 Mar 2022
Image: The BD LSR Fortessa X-20 is a premium flow cytometer that brings endless possibilities to multicolor cell analysis (Photo courtesy of BD Biosciences)

Stem Cell Architecture Drives Myelodysplastic Syndrome Progression

Researchers from The University of Texas MD Anderson Cancer Center discovered that treatment resistance in patients with myelodysplastic syndromes (MDS) is caused by two distinct classes of stem cells and identified possible therapeutic approaches that target these cells. Their findings, which could have significant benefits for patients with disease progression, were published today in Nature Medicine. More...
10 Mar 2022
Image: The Oxford Nanopore GridION (ONT GridION) allows sequencing of very long native DNA or RNA molecules up to megabase size or more (average generally in the 10-50kb range depending on the sample preparation method) (Photo courtesy of Oxford Nanopore Technologies)

Single Test for Over 50 Genetic Diseases Cuts Diagnosis from Decades to Days

A single DNA test has been developed that can screen a patient's genome for over 50 genetic neurological and neuromuscular diseases such as Huntington's disease, muscular dystrophies and fragile X syndrome. The new test avoids a 'diagnostic odyssey' for patients that can take decades. The team has shown that the test is accurate. They are now working on validations to make it available in pathology labs. They expect it to be standard in global pathology labs within five years. More...
09 Mar 2022
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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