Molecular Diagnostics
Distinct Myelodysplastic Syndrome Subtypes Identified by Genomic, Transcriptomic Analysis
Myelodysplastic syndrome is a premalignant disease that affects myeloid cell. It is a precursor to acute myeloid leukemia, an aggressive blood cancer caused by the accumulation of immature blood cells. More...23 Dec 2019
Genome Wide Sequencing Study Reveals Why Some Cystic Fibrosis Patients Develop Fewer Lung Infections
Results published in a recent paper provided an explanation at the molecular level as to why some cystic fibrosis patients have a reduced tendency to contract chronic lung infections. More...23 Dec 2019
Virome Shifts Analyzed in Children with Islet Autoimmunity
Viruses are implicated in autoimmune destruction of pancreatic islet β cells, which results in insulin deficiency and type 1 diabetes (T1D). Certain enteroviruses can infect β cells in vitro, have been detected in the pancreatic islets of patients with T1D and have shown an association with T1D. More...19 Dec 2019
Exposure to Human Cytomegalovirus Increases Aggressiveness of Glioblastoma and Predicts a Poorer Outcome of the Disease
Glioblastoma patients who tested positive for antibodies indicating exposure to human cytomegalovirus (HCMV) had more aggressive tumors and poorer prognosis than patients without anti-HCMV antibodies. More...19 Dec 2019
Single-Cell Analysis Uncovers Regulatory Program in Rare Leukemia
Identifying the causes of human diseases requires deconvolution of abnormal molecular phenotypes spanning DNA accessibility, gene expression and protein abundance. Mixed-phenotype acute leukemia exhibits features of both acute myeloid leukemia and acute lymphoblastic leukemia and, as such, is marked by features of multiple hematopoietic lineages. More...18 Dec 2019
In Other News
Genetic Biomarkers Associated with Autism Spectrum Disorders Identified
Implement Diagnostics System Improves Infectious Disease Testing
Mutations Causing Loss of Tumor Suppressor Gene Increase Aggressiveness of Rare Bile Duct Cancer
Childhood Kidney Cancer Arises from Altered Normal Tissue
Predicting Age by Profiling Circulating Plasma Proteins
A Rapid Method for Selecting the Proper Antibiotic to Treat Multidrug Resistant Bacteria
Chronic Comorbidities Are Prevalent Among People with Chagas Disease
A One-step Rapid Point-of-Care Assay for Diagnosis of Celiac Disease
Diagnosis and Monitoring of Patients with Hepatitis C Virus
TP53 Gene Promoter Methylation Impacts Chronic Lymphocytic Leukemia
Three Factors Distinguish MODY, a Rare Diabetes, in Youth
Alzheimer's Disease Gene Expression Varies by Brain Cell Type
Diagnosing Disease Conditions by Analyzing Plasma Protein Expression Patterns
Home Urine Collection for More Accurate Prostate Cancer Detection
Genetic Architectures of Schizophrenia Compared in Different Populations
Marker Panel Detects Early Liver Cancer with Increased Sensitivity
Rare Genetic Variants Associated with Sudden Cardiac Death
CRISPR-based Electrochemical Biosensor Detects Disease-related MicroRNAs
Gene Panel Predicts Failure of Cutaneous Leishmaniasis Treatment
Genetic Locus with Unique Tandem Repeats Linked to Development of Late-onset Alzheimer’s Disease
Multiplex Panel Debuts for Multi-Drug Resistant Infection Screening
Non-coding Regions of the Genome in Microglia Linked to Alzheimer’s Disease Risk
Epigenetic DNA Biomarkers Pinpoint Infertile Men and Predict Potential Success of Treatment
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.