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Molecular Diagnostics

Image: Thermo Ion Torrent Genexus Sequencer Instrument (Photo courtesy of Thermo Fisher Scientific)

Thermo Fisher Launches CE-IVD Marked NGS Instrument for Diagnostic Testing

Thermo Fisher Scientific (Waltham, MA, USA) has launched the CE-IVD marked Ion Torrent Genexus Dx Integrated Sequencer, an automated, next-generation sequencing (NGS) platform that delivers results in as little as a single day. Designed for use in clinical laboratories, the fully validated system enables users to perform both diagnostic testing and clinical research on a single instrument. More...
31 Mar 2022
Image: New assay quantifies NFL in human serum, plasma or CSF (Photo courtesy of Siemens Healthineers)

Siemens sNfL Blood Test Predicts Risk of MS Disease Activity

The ADVIA Centaur serum Neurofilament Light Chain (sNfL) assay, developed by Siemens Healthineers (Erlangen, Germany) in collaboration with Novartis Pharma AG (Basel, Switzerland), quantitatively measures NfL in human serum and plasma. It is intended to be used in conjunction with clinical, imaging, and laboratory findings as an aid in identifying adult patients with Relapsing Multiple Sclerosis who are at lower risk versus higher risk of MS disease activity. More...
31 Mar 2022
Image: New test predicts sepsis soon after infection — well before blood clotting and organ failure (Photo courtesy of Unsplash)

Rapid Test Predicts Sepsis Soon After Infection and Before Organ Damage

In a potential paradigm change for sepsis diagnostics, a new test predicted sepsis soon after infection in mice - well before blood clotting and organ failure - enabling early antibiotic treatment and markedly increased survival. More...
30 Mar 2022
Image: NGS-based panels detect DNA and RNA cancer biomarkers from FFPE tissue specimens (Photo courtesy of Unsplash)

NGS Panels Detect RNA and DNA Cancer Biomarkers in Single Assay

Vela Diagnostics (Singapore) has launched its new OncoKey SL 60 and 525 Plus Panels. These next-generation sequencing (NGS)-based panels are intended for detection of DNA and RNA cancer biomarkers from formalin-fixed paraffin-embedded (FFPE) tissue specimens, for up to 64 samples in a single sequencing run. More...
30 Mar 2022
Image: New method of developing diagnostic tests could help tackle future pandemics (Photo courtesy of Pexels)

Novel System to Accelerate Development of New Diagnostic Tests

Researchers have developed a more generalizable approach to the creation of new tests, building a software tool capable of turning the reaction graphs into suggestions as to how chemical primers and reactions could be used to create the desired diagnostic results. The software which helps speed up the process of creating new diagnostic tests could help combat future pandemics, its developers say. More...
29 Mar 2022
Image: Sentinel can detect prostate cancer from a single urine specimen (Photo courtesy of miR Scientific)

Urine Liquid Biopsy Test Detects Molecular Evidence of Prostate Cancer

A standalone, non-invasive liquid biopsy urine test can, from a single urine specimen, accurately detect molecular evidence of prostate cancer and, if cancer is detected, classify the severity, or the risk grade, of the malignancy. More...
29 Mar 2022
Image: Applied Biosystems 7900HT Sequence Detection System is designed for automated, high-throughput detection of fluorescent PCR-related chemistries (Photo courtesy of Grizzly Analytical)

BDNF Risk Variant Linked to Brain Inflammation in RRMS Patients

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) that is nowadays representing one of the main causes of disability in young people. The clinical course of MS is highly variable and reflects the complex pathogenesis characterized by inflammation and neurodegeneration already detectable in the initial stages of the disease. More...
28 Mar 2022
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