Molecular Diagnostics
Blood Test to Diagnose Skin Cancer May Help Avoid Invasive Skin Biopsies
Recent advances in liquid biopsy have proposed less-invasive alternatives for cancer diagnosis and monitoring using minimal invasion at sample collection, and circulating tumor cells (CTCs) have been considered a promising blood-based surrogate marker of primary tumors. Now, new research indicates that testing an individual’s blood can reveal the presence of CTCs. Such tests may allow patients to forego invasive skin biopsies to determine whether they have skin cancer. More...21 Apr 2022
Tumor Suppressor Adenomatous Polyposis Coli Regulates T Lymphocyte Migration
Familial adenomatous polyposis (FAP) is an autosomal dominant inherited disease that often results from germline mutations in the adenomatous polyposis coli (APC) gene, a tumor suppressor and polarity regulator. APC protein regulates the Wnt/β-catenin signaling pathway as a component of the β-catenin destruction complex. More...20 Apr 2022
NGS Technology-Based Assay Detects Minimal Residual Disease in Patients with Lymphatic Hematological Tumors
A new assay based on high-throughput next generation sequencing (NGS) technology can test the CDR3 regional sequence of the IgH/K/L gene of the B cell receptor (BCR) in bone marrow samples collected from patients with B lymphpocytic leukemia (B-ALL/CLL) and multiple myeloma (MM) before and after the treatment. More...20 Apr 2022
World’s First Rapid Oral Cancer Test to Revolutionize Diagnosis and Treatment
Researchers at Queen Mary University of London (London, UK) have developed the world’s first PCR test for mouth cancer that may improve the early detection of oral cancer. The test is quick and easy. It only needs the PCR machine used in COVID testing and a technician to operate it. It could be rapidly rolled out around the world at very little extra cost. More...14 Apr 2022
Broad Gene Panel Diagnoses Patients With Kidney Disease
Chronic kidney disease (CKD) is a major public health issue in the USA. Identification of monogenic causes of CKD, which are present in ∼10% of adult cases, can impact prognosis and patient management. For the ∼800,000 individuals in the USA with end-stage kidney disease (ESKD), genetic diagnosis may inform the selection of potential-related kidney donors, assess the risk of disease recurrence, and guide clinical management following transplant. More...13 Apr 2022
Single-Cell RNA-Seq Reveals Cell Type–Specific Molecular and Genetic Associations to Lupus
Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease with elevated prevalence in women and individuals of Asian, African, and Hispanic ancestry. SLE is a disease in which the immune system attacks its own tissues, causing widespread inflammation and tissue damage in the affected organs. It can affect the joints, skin, brain, lungs, kidneys, and blood vessels. More...12 Apr 2022
New
Gold Member
Nucleic Acid Extractor System
NEOS-96 XT
New
Automated Immunoblots Processor
BlueDiver Instrument II
Rapid Molecular Testing Device
FlashDetect Flash10
In Other News
Lyo-Ready PCR Reagents Make Ultra-Sensitive Diagnostics Development Painless
Smartphone-Powered Microfluidic ‘Lab on a Strip’ Dengue Test More Powerful Than LFT Testing
Single-Cell RNA Sequencing Identifies Mechanisms Underlying Autoimmune Diseases
Cervicovaginal DNA Virome Alterations Associated with Genital Inflammation
High-Throughput Screening Assay Identifies Drugs to Treat Resistant Prostate Cancer
Circulating Levels of Anti-Müllerian Hormone Can Identify Premenopausal Women Prior to Significant Bone Density Loss
POC Sepsis Diagnostic Platform to Speed up Clinical and Treatment Decision Making
AI-Powered Voice-Activated Pipettes Streamline Processes and Increase Lab Productivity
Liquid Biopsy Enables Early Cancer Detection in Li-Fraumeni Syndrome Patients
World-First Bedside Genetic Test Identifies Susceptibility to Deafness in Newborn Babies
World-First Bedside Genetic Test Identifies Susceptibility to Deafness in Newborn Babies
Blood Test to Detect Protein Biomarkers Identified Using Breast Milk Could Enable Breast Cancer Screening
Newly Identified Biomarkers Detect Subcortical Small-vessel Disease
miRNA-Based Blood Borne Diagnostic Test Holds Potential for Management of Cancer Patients
Liquid Biopsy Can Detect Recurrent Breast Cancer and Monitor Progression
Thermo Fisher Launches CE-IVD Marked NGS Instrument for Diagnostic Testing
Siemens sNfL Blood Test Predicts Risk of MS Disease Activity
Rapid Test Predicts Sepsis Soon After Infection and Before Organ Damage
NGS Panels Detect RNA and DNA Cancer Biomarkers in Single Assay
Novel System to Accelerate Development of New Diagnostic Tests
Urine Liquid Biopsy Test Detects Molecular Evidence of Prostate Cancer
BDNF Risk Variant Linked to Brain Inflammation in RRMS Patients
Blood Levels of Glial Fibrillary Acidic Protein Predict Dementia Risk in Older Mexican Americans
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
