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Molecular Diagnostics

Image: Human prostate specific antigen (PSA) with bound substrate from complex with antibody (Photo courtesy of Wikimedia Commons)

A Novel Lateral Flow Immunoassay System for Determination of Prostate Specific Antigen

A recent paper described the development of a highly portable quantitative screening test for prostate cancer. More...
10 Jan 2022
Image: Microscope image of the cells used to test nanoparticles (Photo courtesy of Jordan Green; Johns Hopkins Medicine)

New Color-Coded Test Quickly Reveals If Medical Nanoparticles Deliver Their Payload into Target Cells

A color-coded test for new nanoparticles can quickly identify which formulations will effectively deliver the medicines they carry. More...
07 Jan 2022
Image: A) NDUFS1 immunohistochemistry staining of prostate cancer (PCa) tissue microarray (TMA) samples and B) ATP5O immunohistochemistry staining of PCa TMA samples. Staining intensity as per number. Scale bar = 100 µm (Photo courtesy of Medical University of Vienna)

Novel Protein Biomarkers Identified for Prostate Cancer Aggressiveness

Prostate cancer is the most commonly diagnosed cancer in men and is among the top five causes of cancer-related death. In most cases, prostate cancer can be successfully treated but there is a group of patients who suffer an aggressive course and often fatal outcome. More...
05 Jan 2022
Image: The 21 HPV GenoArray Diagnostic Kit for the rapid and accurate HPV genotyping macro array for 21 human papillomavirus identification (Photo courtesy of Hybribio Ltd)

Menstrual Blood Testing With Capture Sequencing Detects High-Risk Human Papillomavirus

Persistent infection of high-risk human papillomavirus (hrHPV) is associated with various HPV-related pre-cancers and cancers. In recent years, HPV testing has gradually become the primary method for cervical cancer screening. More...
04 Jan 2022
Image: Crystallographic structure of sex hormone binding globulin (SHBG) (Photo courtesy of Wikimedia Commons)

Sex Hormone–Binding Globulin Is a Biomarker for Cardiovascular Disease Risk Independent of Total Testosterone Concentration

The blood protein sex hormone–binding globulin (SHBG) has been shown to be a biomarker that predicts greater risk of myocardial infarction and lower risk of ischemic stroke and heart failure in men between the ages of 40 and 69. More...
03 Jan 2022
Image: FastDNA Spin Kit for Soil quickly and efficiently isolates PCR-ready genomic DNA (Photo courtesy of MP Biomedicals)

Parkinson’s Disease Patients Have More Inflammatory Bacteria in Their Noses

Parkinson’s disease (PD) is a complex neurodegenerative disease characterized by nigrostriatal degeneration resulting in bradykinesia, rigidity, tremor, and gait dysfunction. Non-motor symptoms are also typically present, including depression, constipation, and alteration of smell. Diminished sense of smell (hyposmia), is a common hallmark of prodromal PD. More...
29 Dec 2021
Image: The synaptic sheddome: protein ectodomains shed into the cerebrospinal fluid (Photo courtesy of Dr. Peter Penzes, Northwestern University)

Certain Protein Ectodomains in Cerebrospinal Fluid Are Diagnostic Biomarkers for Autism

Abnormally low levels of a protein biomarker, which can be detected in the cerebrospinal fluid (CSF), have the potential to be the basis for diagnosis of autism and related neurological disorders. More...
27 Dec 2021
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.