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Molecular Diagnostics

Image: NGS-based panels detect DNA and RNA cancer biomarkers from FFPE tissue specimens (Photo courtesy of Unsplash)

NGS Panels Detect RNA and DNA Cancer Biomarkers in Single Assay

Vela Diagnostics (Singapore) has launched its new OncoKey SL 60 and 525 Plus Panels. These next-generation sequencing (NGS)-based panels are intended for detection of DNA and RNA cancer biomarkers from formalin-fixed paraffin-embedded (FFPE) tissue specimens, for up to 64 samples in a single sequencing run. More...
30 Mar 2022
Image: New method of developing diagnostic tests could help tackle future pandemics (Photo courtesy of Pexels)

Novel System to Accelerate Development of New Diagnostic Tests

Researchers have developed a more generalizable approach to the creation of new tests, building a software tool capable of turning the reaction graphs into suggestions as to how chemical primers and reactions could be used to create the desired diagnostic results. The software which helps speed up the process of creating new diagnostic tests could help combat future pandemics, its developers say. More...
29 Mar 2022
Image: Sentinel can detect prostate cancer from a single urine specimen (Photo courtesy of miR Scientific)

Urine Liquid Biopsy Test Detects Molecular Evidence of Prostate Cancer

A standalone, non-invasive liquid biopsy urine test can, from a single urine specimen, accurately detect molecular evidence of prostate cancer and, if cancer is detected, classify the severity, or the risk grade, of the malignancy. More...
29 Mar 2022
Image: Applied Biosystems 7900HT Sequence Detection System is designed for automated, high-throughput detection of fluorescent PCR-related chemistries (Photo courtesy of Grizzly Analytical)

BDNF Risk Variant Linked to Brain Inflammation in RRMS Patients

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) that is nowadays representing one of the main causes of disability in young people. The clinical course of MS is highly variable and reflects the complex pathogenesis characterized by inflammation and neurodegeneration already detectable in the initial stages of the disease. More...
28 Mar 2022
Image: An astrocyte cell grown in tissue culture stained with antibodies to GFAP and vimentin (Photo courtesy of Wikimedia Commons)

Blood Levels of Glial Fibrillary Acidic Protein Predict Dementia Risk in Older Mexican Americans

A protein biomarker in the blood was identified that may help predict the likelihood of developing dementia among Mexican Americans over the age of 50. More...
28 Mar 2022
Image: Oral squamous cell carcinoma (Photo courtesy of 123rf.com)

A Minimally Invasive PCR Test for Diagnosis of Oral Cancer

A team of British researchers has adapted the PCR method - now well known for the detection of the COVID-19 virus - for the precise diagnosis of oral squamous cell carcinoma (mouth cancer). More...
25 Mar 2022
Image: New rapid diagnostic test to detect signs of a stroke or other brain injury (Photo courtesy of TETDiagnostics)

Enzyme-Based Point-of-Care Test Could Rapidly Identify Stroke Patients upon Arrival at Hospital

Researchers at Cornell University (Ithaca, NY, USA) have developed a new test that could rapidly identify stroke patients upon arrival at the hospital, so that more patients could receive a CT scan and the clot-dissolving medicine tPA within the critical window. The researchers plan to develop this enzyme-based technology into a range of diagnostic tests that can be performed anywhere using a handheld device. Their initial research has shown that the test effectively diagnoses stroke and concussions. More...
25 Mar 2022
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.