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Molecular Diagnostics

Image: Neuroblastoma circulating tumor cells (CTCs) expressing characteristic genetic biomarkers were isolated using cell size-based separation (Photo courtesy of Frontiers in Oncology (2022). DOI: 10.3389/fonc.2022.939460)

A Novel Gene Signature Predicts Likelihood of Neuroblastoma Relapse

Cancer researchers identified distinct circulating tumor cell and disseminated tumor cell gene expression signatures that distinguished neuroblastoma patients with bone marrow metastases at initial diagnosis, and that persisted in patients with subsequent relapse. More...
07 Oct 2022
Image: DiaSorin will develop, verify, and clinically validate the FDA- cleared and CLIA-waived LIAISON NES POC analyzer (Photo courtesy of DiaSorin)

State-Of-The-Art POC Molecular System to Allow Untrained Operators to Perform Testing for Viral and Bacterial Pathogens

DiaSorin (Saluggia, Italy) has announced that DiaSorin Molecular LLC will collaborate with the Biomedical Advanced Research and Development Authority (BARDA), to support the FDA 510(k) clearance of a CLIA-waived molecular solution for infectious disease testing. More...
07 Oct 2022
Image: An “archaeological excavation” unearthing fungi within cancerous tumors (Photo courtesy of Ella Maru Studio)

Blood Test to Screen for Fungus May Offer Brand-New Method for Early Cancer Detection

Cancer tumors contain multiple species of fungi that differ per tumor type, according to a large study which potentially has implications for the diagnosis and treatment of cancer, as well as for the detection of cancer through a blood test. More...
07 Oct 2022
Image: The PancreaSeq genetic test for pancreatic cancer outperforms current guidelines (Photo courtesy of Pexels)

Molecular Test Accurately Classifies Pancreatic Cysts as Potentially Cancerous or Benign

A molecular test can accurately classify pancreatic cysts as potentially cancerous or benign, marking a critical step toward a precision medicine approach to detecting and treating pancreatic cancer, which has one of the lowest survival rates of all cancers. More...
06 Oct 2022
Image: Peering into single cells reveals key processes in acute kidney injury (Photo courtesy of Pexels)

New Insights into Molecular Interactions Pave Way for Rapid AKI Diagnostic Tests

A research team has used single-cell sequencing techniques to uncover the molecular processes associated with acute kidney injury (AKI). The team has discovered novel gene expression patterns of injured kidney cells that may lead to new therapeutic approaches and strategies for biomarker discovery. More...
06 Oct 2022
Image: The OraQuick Ebola Rapid Antigen Test (Photo courtesy of OraSure)

Next-Gen Ebola Test to Offer Improved Sensitivity and More Automation

Efforts are now on to develop a second-generation Ebola test that would offer improved sensitivity, increased shelf life, new chemistry and more automation when compared to the current test. More...
05 Oct 2022
Image: New heart attack insight could lead to better survival rates after surgery (Photo courtesy of Imperial College London)

Troponin Testing Could Improve Timing of Heart Surgery and Survival Rate

A new study has found that some patients who have lower levels of troponin would benefit from having earlier surgery, although patients with very high troponin levels should have surgery postponed, as their risk of dying was higher if surgery was performed within 10 days of their heart attack. More...
04 Oct 2022
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.