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Molecular Diagnostics

Image: Researchers have identified new molecules involved in diabetes (Photo courtesy of Pexels)

New Study to Help Identify Accurate microRNA Biomarkers for Early Detection and Treatment of Diabetes

Over the past two decades, researchers have conducted studies with animal or cell-based models which have suggested that specific small RNA molecules, called microRNAs, involved in controlling which genes are turned on and off in cells could help pancreatic islets develop and function normally. However, the specific role of these microRNAs in human pancreatic islets was poorly characterized. Now, a new large-scale genetic analysis has identified a set of microRNAs in pancreatic islets that are strongly associated with type 2 diabetes. More...
14 Feb 2023
Image: D-dimer can help in making the difficult diagnosis of prosthetic joint infection (Photo courtesy of Pexels)

D-Dimer Blood Test Detects Prosthetic Joint Infections as Accurately as Standard Tests

Plasma D-dimer, a test commonly used for certain blood clot-related disorders, is a potentially useful marker of infection and has been validated for use in the diagnosis of periprosthetic joint infection (PJI). However, some studies have raised concerns over the diagnostic performance of D-dimer testing for PJI, and its true accuracy is still unknown. Now, a new study suggests that the measurement of plasma D-dimer levels can provide useful information when making the difficult diagnosis of PJI. More...
13 Feb 2023
Image: Plasmon-enhanced LFAs (p-LFAs) improve inexpensive, readily available rapid tests to desired levels of sensitivity (Photo courtesy of WUSTL)

New Diagnostic Test 1,000 Times More Sensitive than Conventional Tests

In their effort to overcome the limitations of point-of-care diagnostic tests, researchers have now developed ultrabright fluorescent nanolabels called plasmonic-fluors, which can be quickly integrated into the lateral flow assay (LFA), a common testing platform. Plasmon-enhanced LFAs (p-LFAs) improve inexpensive, readily available rapid tests to the levels of sensitivity required by physicians for confidence in test results without the need for lab-based confirmation. More...
13 Feb 2023
Image: Researchers have identified a new biomarker of early-stage Alzheimer’s disease (Photo courtesy of Pexels)

Unique Biomarker Could Lead to Diagnostic Tests for Detection of Early-Stage Alzheimer’s

Researchers have identified a new protein in the cerebrospinal fluid that can reliably detect endothelial injury in patients with Alzheimer’s disease. Using this biomarker, they found that endothelial injury is a key contributor to cognitive impairment during the earliest pre-symptomatic stages of the disease as well. More...
10 Feb 2023
Image: The small, voice-activated device extracts and pretreats bacterial DNA (Photo courtesy of ACS Sensors)

Voice-Activated Sample Pre-Treatment Device Enables Hands-Free, Safer DNA Handling

Scientists using samples containing pathogens work with the smallest amounts possible in order to avoid accidental infection. Now, the same technology used by smart voice assistants could also make the laboratory a safer place for scientists and technicians handling infectious samples. More...
10 Feb 2023
Image: The new AI virus diagnostic test could replace current testing methods (Photo courtesy of University of Oxford)

World’s First AI-Powered Diagnostic Test Accurately Identifies Respiratory Viruses in Five Minutes

A world-first diagnostic test powered by AI that can identify known respiratory viruses within five minutes from just one nasal or throat swab could replace current testing methods which are limited to testing for just one infection or are either lab-based and time-consuming or fast and less accurate. More...
09 Feb 2023
Image: The new blood test detects prostate cancer with greater accuracy than current methods (Photo courtesy of Pexels)

New Blood Test Detects Prostate Cancer With 94% Accuracy

Prostate cancer is the most common cancer in men, creating the need for a blood test that can detect it with greater accuracy. Now, new research shows that the (Prostate Screening EpiSwitch) ‘PSE’ blood test is 94% accurate and much superior than the currently used prostate-specific antigen (PSA) blood test. More...
09 Feb 2023
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