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Molecular Diagnostics

Image: Applied Biosystems ABI 373 XLDNA sequencer (Photo courtesy of Perkin-Elmer).

Nosocomial Environmental Contamination by MERS-CoV Investigated

Although Middle East Respiratory Syndrome coronavirus is characterized by a risk of nosocomial transmission, the detailed mode of transmission and period of virus shedding from infected patients are poorly understood.   More...
04 Jan 2016
Image: A screenshot from the Mykrobe Predictor software package shows results for an analysis of a methicillin-resistant Staphylococcus aureus (MRSA) bacterium (Photo courtesy of Mykrobe [University of Oxford]).

Computer Program Predicts Drug Resistance by Evaluating Whole Genome Sequencing Data

A software package is being evaluated in the United Kingdom that can identify a bacterium from the DNA sequence of its genome and predict which antibiotics will kill it.  More...
03 Jan 2016

Low Zinc May Indicate Potential Breast-Feeding Problems

A new study provides an important step toward identifying breast-fed infants at risk for severe zinc deficiency. Identifying mothers with abnormally low levels of zinc in breast milk may enable to more quickly determine those more likely to have trouble breast-feeding.   More...
27 Dec 2015
Image: Immunohistochemistry of estrogen receptor (ER)-positive (brown), in metastatic breast cancer (Photo courtesy of Dr. Steven Halls).

Different Mutations May Predict Different Responses to Chemotherapy

Among patients with estrogen receptor-positive, metastatic breast cancer, those who had a D538G and/or a Y537S mutation in the estrogen receptor 1 gene, as detected in cell-free DNA obtained from patient blood samples, had significantly worse median overall survival.  More...
21 Dec 2015
Image: Karyotype for trisomy 21 or Down\'s syndrome: the image clearly shows the three copies of chromosome 21 (Photo courtesy of Wikimedia Commons).

Study Validates Use of Noninvasive Test for Defective Fetal Chromosomes

A German biomedical company has reported the successful validation of its qPCR-based noninvasive test for fetal genetic abnormalities such as trisomy 21.  More...
13 Dec 2015
Image: BioMark HD Real Time Polymerase Chain Reaction System (Photo courtesy of Fluidigm).

Molecular Methods Differentiate E. coli Outbreaks

The public health importance of Shiga toxin-producing Escherichia coli infections, epidemiological and molecular surveillance systems are essential for early outbreak detection and in recent years, rapid advancements in the use of molecular typing methods have improved STEC surveillance and outbreak detection.  More...
09 Dec 2015
Image: The MiSeq Next-Generation Sequencing System (Photo courtesy of University of Lausanne).

Germline Genes Mutations Associated with Pediatric Cancer Predisposition

The prevalence and spectrum of predisposing mutations among children and adolescents with cancer are largely unknown, but knowledge of such mutations may improve the understanding of tumorigenesis, direct patient care, and enable genetic counseling of patients and families.  More...
06 Dec 2015
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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