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Molecular Diagnostics

Image: A colored scanning electron micrograph (SEM) of a dividing cervical cancer cell (Photo courtesy of Wellcome Images).

New Methylation Test Determines Cervical Cancer Risk

A novel CE-IVD-marked diagnostic triage test for use in differentiating patients’ risk of developing cervical cancer (CC) will soon be available in Europe, Middle East, and Africa for use on either clinician- or self-collected specimens. Self-sampling can streamline processes and help avoid unnecessary further medical intervention. As a follow-up assay, the test helps risk-stratify patients with transforming human papillomavirus (HPV) infections. More...
28 Jun 2016
Image: Neurons in the brain. Researchers have identified a DNA variant that appears to regulate levels of glutamate - a chemical, known as a neurotransmitter, which transports messages between neurons in the brain (Photo courtesy of Dr. Jonathan Clarke, Wellcome Images).

Wide-ranging Genomic Study Links Migraine-Related Genes to the Vascular System

Results from 22 genome-wide association (GWA) studies conducted by dozens of researchers worldwide suggest that migraine is linked to specific gene loci that are associated with some vascular disease or are involved in the regulation of vascular tone. More...
27 Jun 2016
Image: The Agilent Bioanalyzer microfluidics-based platform (Photo courtesy of Agilent Technologies).

Blood Test Predicts Personalized Depression Treatment

A blood test has been developed that accurately and reliably predicts whether depressed patients will respond to common antidepressants, which could herald a new era of personalized treatment for people with depression. More...
22 Jun 2016
Image: A blood film of a pediatric patient with B-cell precursor acute lymphoblastic leukemia (Photo courtesy of Dr. Peter Maslak, MD).

Two New Types Of Childhood Leukemia Discovered

Acute lymphoblastic leukemia is a rare disease, but the most common form of cancer in children and nowadays the treatment is very successful, but requires intense interventions at the risk of causing many side effects. More...
22 Jun 2016
Image: A SURVIV analysis of breast cancer isoforms developed at UCLA. Blue lines are associated with longer survival times, and magenta lines with shorter survival times (Photo courtesy of Professor Yi Xing).

Biomarkers Could Give Cancer Patients Better Survival Estimates

Cancer patients are often told by their doctors approximately how long they have to live, and how well they will respond to treatments, but there is a way to improve the accuracy of doctors' predictions. More...
21 Jun 2016
Image: The Guardant360 kit for biopsy-free tissue sequencing for cancer (Photo courtesy of Guardant Health).

Comprehensive Liquid Biopsy Guides Metastatic Cancer Treatment

Liquid biopsies offer a promising approach for identifying druggable genomic alterations, which is the ability of a portion of a genome to be targeted by a drug, especially by a small molecule drug, without the need for costly and invasive tissue biopsies. More...
21 Jun 2016
Image: The MassARRAY system for iPlex single nucleotide polymorphism (SNP) genotyping (Photo courtesy of Sequenom).

Genes Identified That Increase Children's Risk Of Blood Infection

Bacteremia is a bacterial infection of the bloodstream, and a major cause of illness and death in sub-Saharan Africa but little is known about whether human genetics play a part. More...
16 Jun 2016
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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