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Molecular Diagnostics

Image: Immunochemistry of receptors for estrogen (ER), strong and diffuse nuclear staining in a tissue sample from a breast cancer patient (Photo courtesy of Steven Halls, MD).

Multigene Test Identifies Early Breast Cancer

The 21-gene Recurrence Score assay, nodal status, grade, and immunohistochemical markers are recommended for chemotherapy decision making in hormone receptor positive/ human epidermal growth factor receptor negative early breast cancer.  More...
30 Mar 2016
Image: The ABI 7900HT Fast Real-Time Polymerase Chain Reaction (PCR) System (Photo courtesy of Applied Biosystems).

Blood Test Gives Early Warning of Melanoma Relapse

Targeted immunotherapies have transformed melanoma care, extending median survival from around 9 to over 25 months but nevertheless, most patients still die of their disease and although most melanoma patients respond to treatment at first, their cancer can become resistant within a year.   More...
21 Mar 2016
Image:  Clostridium difficile colonies after 48 hours’ growth on blood agar plate. By competitive exclusion, healthy gut flora help limit growth of pathogenic yeasts and bacteria. Overgrowth of C. difficile in the gut can cause pseudomembranous colitis, and is the most frequently identified cause of antibiotic-associated diarrhea. (Image courtesy of Dr. Holdeman, Centers for Disease Control & Prevention (CDC; image ID #3647), and Wikimedia.)

Robust Method Developed for Microbiome Analysis

Scientists have developed a technique for genome sequence data analysis that enables to more efficiently and accurately identify differences between metagenomes for a variety of bacterial communities, which can help to study, diagnose, and treat many human diseases. In a new study, the method was successfully tested on intestinal microbiota.  More...
16 Mar 2016
Image: A cancer of the iris known as uveal melanoma (Photo courtesy of Dr. Jonathan Trobe, MD).

Biomarker Identifies Uveal Melanoma Patients at Risk for Metastasis

Uveal melanoma is a cancer of the eye involving the iris, ciliary body, or choroid, collectively referred to as the uvea. Tumors arise from the pigment cells that reside within the uvea giving color to the eye.   More...
15 Mar 2016
Image: Schematic diagram of the ultrasensitive solution-phase method for detecting antibodies, by agglutination-polymerase chain reaction (ADAP) (Photo courtesy of the University of California, Berkeley).

Ultrasensitive Antibody Detection Enabled by Agglutination-PCR

Antibodies are widely used biomarkers for the diagnosis of many diseases and assays based on solid-phase immobilization of antigens comprise the majority of clinical platforms for antibody detection, but can be undermined by antigen denaturation and epitope masking.   More...
14 Mar 2016
Image: Schematics of workflow for whole-exome sequencing (Photo courtesy of Quest Diagnostics).

Whole-Exome Sequencing Identifies Rare Inherited Diseases

Whole-exome sequencing could serve as a viable diagnostic approach for identifying rare inherited diseases and providing a resolution for patients on a diagnostic odyssey, which are patients with a suspected genetic condition for whom previous standard genetic testing did not reveal a cause.  More...
14 Mar 2016
Image: Histopathological findings in laryngeal squamous cell carcinoma (Photo courtesy of Nikon Microscopy).

Gene Predicts Outcomes for Head and Neck Patients

A human cancer-causing gene, called the DEK oncogene, can be detected in the plasma of head and neck cancer patients and this may help doctors understand how a person's immune system could be used to treat cancer or predict outcomes for patients.   More...
08 Mar 2016
New
Gold Member
Neonatal Heel Incision Device
Tenderfoot
POC Helicobacter Pylori Test Kit
Hepy Urease Test
New
Food Allergy Screening ELISA Kit
Allerquant 14G B ELISA
New
Japanese Encephalitis Test
Japanese Encephalitis Virus Real Time PCR Kit


Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.