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Molecular Diagnostics

Image: The Applied Biosystem Veriti Thermal Cycler (Photo courtesy of Life Technologies).

High-Risk Female Groups Screened for Fabry Disease

Although measurement of lysosomal α-galactosidase A in women is not accurate for the diagnosis of Fabry disease, determining the range of the enzyme activity presented by heterozygous females could become a valuable tool for minimizing the burden of screening by DNA sequencing all potential carriers.   More...
26 Jun 2014
Image: The 3730xl DNA Analyzer (Photo courtesy of Applied Biosystems).

Molecular Makeup Uncovered in New Form of Cancer

The molecular signature and genetic structure has been revealed of a new form of cancer that begins in the nose and is called biphenotypic sinonasal sarcoma.   More...
25 Jun 2014
Image: Histopathology micrograph of prostatic acinar adenocarcinoma, the most common form of prostate cancer (Photo courtesy of Nephron).

Prostate Cancer Biomarkers Identified in Seminal Fluid

Improved diagnosis and management of one of the most common cancers in men, prostate cancer, could result from discovery that seminal fluid contains biomarkers for the disease.  More...
18 Jun 2014
Image: Histopathology of mammary tissue, high grade breast cancer (Photo courtesy of Johns Hopkins Medicine).

Four New Genes Added to Inherited Breast Cancer Risk List

Based on risk and frequency, three classes of breast cancer susceptibility genes or loci are currently recognized, but four more genes have been added the growing list of higher risk genes.   More...
17 Jun 2014
Image: The Myriad myPath Melanoma test differentiates malignant melanoma from benign skin lesions with a high level of accuracy (Photo courtesy of Myriad Genetics).

New Test Improves Reliability of Melanoma Diagnosis

New results support the use of a novel multigene test as an important adjunct to standard pathology techniques in the evaluation of potentially malignant pigmented skin lesions.  More...
12 Jun 2014
Image: Histopathology of a colon with adenocarcinoma showing chaotic appearance of glandular pattern (Photo courtesy of Johns Hopkins University).

DNA Blood Test Evaluated for Colorectal Cancer Detection

Tumor-derived aberrant DNA can be detectable in blood and blood tests have the potential to improve screening for colorectal cancer.  More...
11 Jun 2014
Image: Karyotype of Trisomy 22 showing three copies of chromosome 22 (Photo courtesy of Ewha Womans University School of Medicine).

New Genetic Sequencing Methods Means Accurate Embryo Screening

The clinical application of next generation DNA sequencing, a high throughput sequencing method, has the potential to revolutionize pre-implantation genetic screening.  More...
10 Jun 2014
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.