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Molecular Diagnostics

Image: The plate on the right was inoculated with a Carbapenem-Resistant Enterobacteriaceae (CRE) bacterium that proved to be resistant to all of the antibiotics tested; bacteria in the left plate are susceptible to the antibiotics on the discs (Photo courtesy of James Gathany).

Common Bacteria May Become Antibiotic-Resistant Superbugs

Pathogenic Enterobacteriaceae, including Escherichia coli and Klebsiella pneumoniae, are major causes of multidrug resistant infections in hospitals worldwide and these pathogens have recently been shown to have acquired resistance to carbapenems.   More...
07 Apr 2015
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Prognostic Marker Identified for Head and Neck Squamous Cell Carcinoma

Molecular profiling may be useful for early diagnosis and treatment decisions for head and neck squamous cell carcinomas.   More...
05 Apr 2015
Image: Scanning electron micrograph of Pseudomonas aeruginosa from cultured biofilms in the respiratory tract of patients with cystic fibrosis (Photo courtesy of Science Photo Library).

New Method Tests for Cystic Fibrosis Infection Pathogens

A new method of testing the most common cause of life-threatening infection in people with cystic fibrosis could improve efforts to study and combat the illness.  More...
31 Mar 2015
Image: Investigators evaluate results of the AQP1 ELISA, part of a noninvasive method to screen for kidney cancer by measuring the presence of protein biomarkers in the urine (Photo courtesy of the Washington University School of Medicine).

Urinary Proteins Kidney Cancer Biomarkers

Two urinary proteins are elevated in individuals with kidney cancer or papillary renal cell carcinoma, and are candidates to serve as biomarkers for early detection of the disease.  More...
29 Mar 2015
Image: Histopathology of tuberculoid leprosy in a skin section (Photo courtesy Dr. D.S. Ridley, Wellcome Images).

Genes Discovered Influence Risk of Developing Leprosy

Leprosy, a chronic dermatological and neurological disease, is caused by infection withMycobacterium leprae, and its manifestation, progression and prognosis are strongly associated with the proficiency of the patient's immune system.  More...
25 Mar 2015

Gene Expression Profile Identifies Autistic Infants and Toddlers

A team of neuroscientists has developed a prototype blood-based assay that is able to differentiate children with normal development from those with autism when they are as young as one to two years.   More...
24 Mar 2015
Image: Histopathology of cerebral diffuse beta amyloid plaque (Photo courtesy of Dr. Dimitri P. Agamanolis, MD).

Blood-Based Test Developed for Diagnosing Alzheimer's Disease

A simple blood test has been developed to confirm the presence of beta amyloid proteins in the brain, which is a hallmark of Alzheimer's disease, and could be a key advance in diagnosing this neurodegenerative disorder.   More...
23 Mar 2015
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