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Clinical Chemistry

Image: Professor Emeritus David Lawrence Sackett, MD (Photo courtesy of McMaster University).

Professor Emeritus David L. Sackett, Developer of Evidence Based Medicine

Professor Emeritus David Lawrence Sackett, MD, widely regarded as the father of evidence based medicine, died on May 13, 2015, in Canada.  More...
01 Jun 2015
Image: The CARY 50 BIO UV-Visible Spectrophotometer (Photo courtesy of Agilent Technologies).

Harmless Bacteria Thrive in Patients with Inflammatory Bowel Disease

The survival and proliferation of usually harmless Escherichia coli in the gut of inflammatory bowel disease patients may now be better understood, as fundamental mechanism through which the bacteria can thrive during flare-ups has been defined.  More...
26 May 2015
Image: Schematic diagram of the DESI ion source (Photo courtesy of Wikimedia Commons).

Mass Spectroscopy Techniques Detect Cocaine Metabolites in Fingerprints

Two mass spectroscopy techniques have been adapted for detecting cocaine and its metabolites benzoylecgonine and methylecgonine from latent fingerprints.  More...
26 May 2015
Image: The Minicap Flex Piercing capillary zone electrophoresis system (Photo courtesy of Sebia).

Capillary Electrophoresis Evaluated for Hemoglobinopathy Testing

The detection of structural hemoglobin variants and thalassemia has become increasingly important in clinical laboratories of all countries with a large influx of immigrants over the past 10 years.  More...
25 May 2015
Image

Blood Markers Help Predict Infant Heart Surgery Outcome

Inflammation and metabolism are closely interlinked and both undergo significant dysregulation following surgery for congenital heart disease, contributing to organ failure and morbidity.  More...
20 May 2015
Image: Schematic illustration of the detection of Troponin 1 using glass vials and capillary tubes with an ink indicator (Photo courtesy of the American Chemical Society).

Thermometer-Like Device Could Help Diagnose Heart Attacks

Diagnosing a heart attack can require multiple tests using expensive equipment, but not everyone has access to such techniques, especially in remote or low-income areas.  More...
18 May 2015
Image: Histopathology of a Brenner tumor, a type of surface epithelial-stromal tumor, which may be benign or malignant, depending on whether the tumor cells invade the surrounding ovarian tissue (Photo courtesy of Nephron).

Ovarian Cancer Screening Technique Doubles Detection Rates

A risk algorithm using serial biomarker measurements doubles the number of screen-detected ovarian cancers compared to a single threshold rule.  More...
18 May 2015
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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