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Clinical Chemistry

Image: The gel zymography separation of matrix metalloproteinases (MMPs) on a 7.5% polyacrylamide gel (Photo courtesy of the Italian National Research Council).

Quantitative Gel Zymography Reappraised for Matrix Metalloproteinases

A reappraisal of quantitative gel zymography technique for matrix metalloproteinases in human plasma has been used for comparison with commercially available enzyme-linked immunosorbent assay.   More...
29 Oct 2014
Image: Immunohistochemical staining of ovarian tissue with anti-CA125 for the diagnosis of ovarian carcinoma; the neoplastic cells are strongly stained (Photo courtesy of Epitomics).

Test Model Discriminates Ovarian Tumors

A new test can discriminate between benign and malignant ovarian tumors, and identify different types of carcinomatous tumors, with a high level of accuracy.  More...
28 Oct 2014
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Serum Prostate-Specific Antigen Measured by Tandem Mass Spectrometry

Prostate-specific antigen is a widely used blood test for detection and monitoring of prostate disease and many clinicians assume that all test methods produce essentially the same results, though differences do exist.   More...
23 Oct 2014

Heart Attack Biomarkers Accurate in Chronic Kidney Disease Patients

Two blood peptide biomarkers that are indicators of heart attack in the general population also provide critical information regarding heart status in chronic kidney disease patients.  More...
19 Oct 2014
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Glucose Monitoring System Cleared for Hospital Critical Care Units

A blood glucose monitoring system has been cleared and its use extended to critically ill patients who have been hospitalized.  More...
16 Oct 2014
Image: The HTS PAL autosampler (Photo courtesy of Leap Technologies).

Newly Discovered Marker Detects Early Pancreatic Cancer

A marker in the blood that may indicate early development of the pancreatic ductal adenocarcinoma could pave the way for an early detection test.  More...
16 Oct 2014
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Type 2 Diabetes Caused by Low Vitamin D Disputed

Low circulating concentrations of 25-hydroxyvitamin D, a marker of vitamin D status, are associated with an increased risk of type 2 diabetes, but whether this association is causal remains equivocal.  More...
16 Oct 2014
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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