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Clinical Chemistry

Image: Spiked rods of uric acid crystals from a synovial fluid sample photographed under a microscope with polarized light (Photo courtesy of Bobjgalindo).

Serum Uric Acid Level Associated With Metabolic Syndrome

Metabolic syndrome is defined by a cluster of risk factors, including obesity, dyslipidemia, hypertension, and insulin resistance, and when occurring together, they increase the risk of developing cardiovascular disease and diabetes.   More...
27 Sep 2015
Image: Combining the Thermo Scientific Prelude MD HPLC (left), Endura MD mass spectrometer (right), and ClinQuan MD software, enables simple and confident attainment of the high quantitative accuracy of LC-MS (Photo courtesy of Thermo Fisher Scientific).

MD HPLC, MD Mass Spec, and Software Receive IVDD CE-Marking

The in vitro diagnostics device CE marking for the two high-performance instruments and software enables a combined system with the high accuracy of LC-MS to now be available to clinical laboratories in Europe for general IVD use.  More...
15 Sep 2015

Saliva Test Identifies Healthy Older People with Cognitive Problems

The saliva of healthy older people should be tested for the level of the stress hormone cortisol and this may help identify individuals who should be screened for problems with thinking skills.  More...
15 Sep 2015

High-Sensitivity Version of Common Blood Test May Predict Early Onset of Hypertension

A study analyzing blood samples from over 5,000 people suggests that a more sensitive version of the standard blood test for cardiac troponin T—long used to verify heart muscle damage from heart attacks—could help identify people on the verge of developing hypertension well before it can be detected with a blood pressure machine.  More...
02 Sep 2015
Image: The Agilent 1200 high-performance liquid chromatography system (Photo courtesy of Marine Biophysics Laboratory).

Biomarkers Identified for Early Lung Cancer Diagnosis

Lung cancer can be diagnosed early with regular low-dose computed tomography scans of people at risk, but these tests are very expensive, and also involve exposing patients to X-ray radiation.  More...
01 Sep 2015
Image: Photomicrograph demonstrating typical multiple myeloma histology, with monoclonal proliferation of plasma cells (Photo courtesy of Ohio State University College of Medicine).

Near Real-Time Osteoporosis and Bone Cancer Test Developed

 A new test which measures changes in calcium isotope ratios offers the possibility of near real time monitoring of bone diseases, such as osteoporosis and multiple myeloma. More...
30 Aug 2015
Image: Schematic representation of the protein biomarkers used in the Cardiac Protein Unstable Lesion Signature (PLUs) test (Photo courtesy of GD Biosciences).

Blood Test Detects Silent Cardiac Disease

A blood test has been developed that detects silent cardiac disease and assesses a person’s risk of suffering from a future cardiac event.   More...
26 Aug 2015
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.