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BioResearch

Human Proteome Catalog Created for Speeding Research and Diagnostic Development

An international team of researchers recently created an initial catalog of the human “proteome,” in an effort to provide a protein equivalent of the Human Genome Project.  More...
30 Jun 2014
Image: This image shows a microscopic view of the high concentration (red) of gamma-aminobutyric acid (GABA) in the reactive astrocytes (green) in the human brain with Alzheimer\'s disease (Photo courtesy of Dr. Gong Chen, Pennsylvania State University).

High GABA Level Astrocytes Are a New Alzheimer's Disease Biomarker and Drug Target

Cells comprising an abnormal class of brain cells called reactive astrocytes contain high levels of the inhibitory neurotransmitter gamma-aminobutyric acid and are being eyed by researchers as a potential biomarker and drug target for Alzheimer's disease.   More...
25 Jun 2014
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New Inverted Microscope Available for Routine Work and Training

A robust inverted light microscope for quick cell culture checking and other routine work is now available for biotech, life science, and clinical laboratories.  More...
25 Jun 2014
Image: Pictured is mouse optic nerve and retina, responsible for relaying information from the eye to the brain. The tissue has been fluorescently stained to reveal the distribution of astrocytes (yellow), retinal ganglion cell axons (purple), myelin (green) and nuclei (cyan). Retinal ganglion cell axons transfer mitochondria to adjacent astrocytes in the optic nerve head behind the retina. Astrocytes degrade the mitochondria in a process called transmitophagy (Photo courtesy of the University of California, San Diego).

Certain Optic Cells Export Their Damaged Mitochondria for Destruction Elsewhere

A recent paper revealed that certain cells in the eye transfer damaged mitochondria to neighboring cells for destruction and recycling.  More...
25 Jun 2014

Rainbow Mouse Model Reveals Secrets of Kidney Regeneration

The ability of the kidney to regenerate following disease or injury has been linked to the activation of the WNT signaling pathway and the generation of segment-specific fate-restricted clones.  More...
24 Jun 2014
Image: Electron micrograph, false color, of group A Streptococcus bacteria (Photo courtesy of the University of California, San Diego).

Creation of a Weakly Virulent Strep A Mutant May Boost Vaccine Development

Creation of a mutated variety of Group A Streptococcus bacteria with reduced virulence but complete immunological expression may pave the way for development of a safe vaccine to prevent infections such as strep throat, necrotizing fasciitis, and rheumatic heart disease, which are caused by these organisms.   More...
23 Jun 2014
Image: Transmission electron micrograph of a cell mitochondrion (Photo courtesy of Thomas Deerinck, NCMIR, UC San Diego).

Dose of 100-Year-Old Drug for Sleeping Sickness Reverses Autism-Like Symptoms in Lab Mice

By exploring a unique hypothesis that suggests autism is a result of faulty cell communication, researchers revealed that a nearly 100-year-old drug approved for treating sleeping sickness has been found to restore normal cellular signaling in a mouse model of autism.  More...
23 Jun 2014
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.