BioResearch
Diabetes Drug Shows Promise as an Anticancer Immunotherapeutic Agent
Treatment with the anti-diabetes drug sitagliptin of some types of cancer in a mouse model was found to increase the infiltration of T lymphocytes into tumors and, in combination with existing immunotherapies, eradicate the tumor. More...30 Jun 2015
Potential Diabetes Drug Works by Relieving Endoplasmic Reticulum Stress
A recent paper linked stress affecting the endoplasmic reticulum to the development of several chronic diseases including diabetes, retinitis pigmentosa, cystic fibrosis, Huntington's disease, and Alzheimer's disease. More...30 Jun 2015
![Image: A colorized scanning electron micrograph (SEM) of a T lymphocyte. Regulatory T-cells (Treg cells) are critically important for preventing the body’s immune response from going overboard and causing autoimmune disease (Photo courtesy of the [US] National Institute of Allergy and Infectious Diseases).](https://globetechcdn.com/mobile_labmedica/images/stories/articles/article_images/2015-06-29/GMS-200.jpg "Image: A colorized scanning electron micrograph (SEM) of a T lymphocyte. Regulatory T-cells (Treg cells) are critically important for preventing the body’s immune response from going overboard and causing autoimmune disease (Photo courtesy of the [US] National Institute of Allergy and Infectious Diseases).")
Hypoxia Factors Contribute to Maintenance of Regulatory T-cell Function
A team of cell biologists has identified a molecular pathway that maintains the stability and function of regulatory T-cells, which are components of the immune system that suppress immune responses of other cells and act as an important “self-check” built into the immune system to prevent excessive reactions. More...29 Jun 2015
License Agreement to Promote Development of Therapeutic CDK Inhibitors
A license agreement has been signed that was designed to promote the development and commercialization of a series of highly-selective cyclin-dependent kinase 7 inhibitors for the treatment of cancer, inflammation, and viral infections. More...29 Jun 2015
Multimillion Dollar Investment Launches Drug Development Research Startup
A global healthcare company with research and development interests in the area of pharmaceuticals, vaccines, and consumer healthcare will be financing an independent startup to promote drug development through advances in the understanding of gene function and control. More...28 Jun 2015
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Acid-Sensitive Nanoparticle Drug Delivery System Targets Cancer Stem Cells
Researchers Pinpoint Binding Site for Clostridium difficile Binary Toxin
Bacterial Toxin Shows Promise as Potential Anticancer Drug
Antibody Cocktail Blocks Growth of Drug-Resistant Lung Tumors in Mouse Model
Monoclonal Antibody Blocks Development of Type I Diabetes in Mouse Model
Structure of Integral Membrane Proteins Readily Solved Using an Alternative In Meso In Situ Serial Crystallography Technique
A Drug That Prevents Lung Damage Protects Mice with Influenza Infection
Novel Phage Treatment Restores Bacterial Sensitivity to Antibiotics
New Version of Old Drug Shows Promise for Treating Drug-Resistant Tuberculosis
Chronic Exposure to Bacterial Superantigens Induces Diabetes-Like Symptoms in Rabbit Model
Mouse Model Demonstrates Importance of Interleukin-6 to Spread of Prostate Cancer
Zebrafish Embryo Model Helps Explain How Coronary Blood Vessels Develop
Proteins in the Tumor Microenvironment Influence Progression of the Disease
Spherical Cell Cultures May Revolutionize the Study of Living Brain Tissues
Innovative Options Augment Multimode Reader Performance
Formation of Adipose Scar Tissue Begins with Activation of Platelet-Derived Growth Factor Receptor Alpha Signaling
Electron Microscopy Reveals How Viral DNA Survives Extremes of Heat and Acidity
Diagnosing Liver Cancer Using Genetically Modified Probiotic Bacteria
Research on Zebrafish Embryos Reveals Origin of the Lymphatic System
BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.