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BioResearch

Image: Scanning electron microscope image of the cross section of a fast relaxing hydrogel containing mesenchymal stem cells. The cells differentiated into osteoblasts and integrated in the matrix (Photo courtesy of Harvard University).

Viscoelastic Hydrogels Promote Bone Formation in 3D Cell Cultures

Stem cell researchers have devised a viscoelastic hydrogel matrix that encourages stem cells grown in three-dimensional culture to differentiate into bone tissue, which has promising applications in the realm of bone regeneration, growth, and healing.  More...
15 Dec 2015
Image: Colorized scanning electron micrograph (SEM) of the ultrastructural details seen in the cell wall configuration of a number of Gram-positive Mycobacterium tuberculosis bacteria (Photo courtesy of the CDC - US Centers for Disease Control and Prevention).

Drugs That Block Sulfur Metabolism Show Potential for Treating Latent Tuberculosis

Drugs that target sulfur metabolism have been found to have potential for treating latent tuberculosis infections, including those caused by drug-resistant forms of the bacteria.  More...
14 Dec 2015
Image: A schematic illustration of the liquid-metal nano-terminators (left). The red spheres are the anticancer drug doxorubicin. A representative TEM image of the liquid-metal nano-terminators (right) (Photo courtesy of North Carolina State University).

Biodegradable Metallic Nanodrops for Safe Cancer Drug Delivery

A novel drug delivery system based on liquid metal nanodrops was used to safely transport the highly toxic chemotherapeutic agent doxorubicin into the cancer cells comprising ovarian tumors in a mouse xenograft model.  More...
14 Dec 2015
Image: Investigators at Kyoto University have demonstrated the potential of a PD-1 antibody, nivolumab, to treat platinum-resistant ovarian cancer (Photo courtesy of Kyoto University).

Nivolumab Found Safe and Effective in Ovarian Cancer Phase II Trial

A team of Japanese cancer researches has demonstrated the safety and effectiveness of the drug Nivolumab for treating women with platinum-resistant ovarian cancer.  More...
13 Dec 2015
Image: Ribbon representation of a repeating unit in the extracellular E-cadherin ectodomain (Photo courtesy of Wikimedia Commons).

Tumors Grow When Normal Cells Are Induced to Become Cancerous

A recent study determined how the cancer cells within a tumor promote its growth by transforming neighboring normal epithelial cells into cancer cells.  More...
13 Dec 2015

Drug Development Agreement Targets Migraine Treatments

A British drug development company is teaming up with a major international pharmaceutical corporation to develop, commercialize, and manufacture treatments for migraine.  More...
13 Dec 2015
Image: SBI-756, a first-in-class compound, halts melanoma growth by disrupting protein production (Photo courtesy of Sanford Burnham Prebys Medical Discovery Institute).

Candidate Melanoma Drug Disrupts Translation Initiation Factor Complexes

A potentially game changing drug for the treatment of malignant melanoma works by breaking up the translation initiation complexes that the cancer cells require in order to translate mRNA into proteins.  More...
09 Dec 2015
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.