BioResearch
Novel Nanocarriers Ferry Anticancer Drugs Across the Blood-Brain Barrier
A recent paper described the development of a novel class of highly stable, long-circulating three-helix micelles (3HM) capable of ferrying chemotherapeutic agents across the blood-brain barrier for the treatment of the deadly brain tumor glioblastoma multiforme (GMB). More...07 Dec 2015
Researchers Culture Novel Three-Dimensional Artificial Tumors
A team of Canadian cancer researchers has developed a novel method for growing three-dimensional cultures of cancer cells that behave as artificial tumors and which can be readily resolved to evaluate the response of individual cells to different levels of oxygen and nutrients. More...07 Dec 2015
Advances in Stem Cell Technology Boost Efforts to Develop a Biological Pacemaker
A recent review article summarized the progress being made in the endeavor to develop permanent biological pacemakers to replace the currently used electronic heart pacemakers, which require regular maintenance and periodic replacement. More...06 Dec 2015
When Exercise Is Unhealthy: Study Sheds New Light on Sudden Cardiac Death
Researchers have discovered new aspects, involving a mutated protein, of a not-well-understood mechanism that underlies how sudden heart failure can occur during endurance exercise in patients with arrhythmogenic ventricular cardiomyopathy, which currently has no standardized guidelines for exercise management. More...06 Dec 2015
Japanese Stem Cell Firm Acquires Scottish Drug Discovery Support Company
In order to facilitate its move into the drug discovery industry, a Japanese stem cell technology company has acquired a Scottish biotechnology company that provides highly characterized human tissues for pharmaceutical development studies. More...06 Dec 2015
Ancient Genomes Reveal Natural Selection During Introduction of Farming in Europe
A new study of ancient genomes has tracked evolutionary changes associated with the introduction of agriculture into Europe about 8,500 years ago, finding particular migrations and lifestyle adaptations reflected down to the molecular level of particular genes. More...02 Dec 2015
Mosquitoes Genetically Modified as Malaria-Blocking Insect Model
Scientists used CRISPR gene editing to create a parasite-resistant strain of Anopheles mosquito capable of rapidly introgressing malaria-blocking genes into a mosquito population through its progeny, ultimately eliminating the insects’ ability to transmit the Plasmodium falciparum parasite to humans. More...02 Dec 2015
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In Other News
Insights into Evolution of Drought-Tolerance Revealed by Pineapple Genome
Advanced Gene Therapy Cures Cystic Fibrosis in Culture and Mouse Models
Smart Incubator System Automates Live Cell Assay Operations
The Structure of the Nasal Cavity Channels Food Smells into the Nose and Avoids the Lungs
How Blocking TROY Signaling Slows Brain Cancer Growth
Actin in the Nucleus Triggers a Process That Directs Stem Cells to Mature into Bone
Platelet Membrane-Coated Nanoparticles Kill Circulating Tumor Cells and Prevent Metastasis in Breast Cancer Model
Broadly Neutralizing Antibodies Protect Mice from Alphavirus Infection
Molecular Light Shed on “Dark” Cellular Receptors
New Bioreactor System Streamlines Strain Screening and Culture
Novel Molecular Signaling Pathway Inhibits Lung Cancer Growth and Metastasis
Inactivated Bacteria and Excreted Factors for Colorectal Cancer Treatment
Potential Drug Candidate Blocks Alternate DNA Repair Route in BRCA-Mutated Cancer Cells
Thermophilic Archaeal Lipids Stabilize Drug-Delivery Liposomes
Microtubule Network Created by Three-dimensional Printing Transports Blood in an Animal Model
New DNA-Based Assay Rapidly Detects E. coli O157:H7 During Food Manufacture
Loss of Tumor Suppressor Gene Spurs Growth of Some Malignant Melanomas
Combination of Genetic and Metabolic Analysis Links Endoplasmic Reticulum Stress to Cardiovascular Disease Risk
A Subset of Immune T-Cells Protects Against Metabolic Syndrome in Mouse Model
Analysis of RNA Carried by Tumor-educated Platelets Yields Valuable Diagnostic Clues
Epidermal Growth Factor Receptor Stimulates Early Cancer Metastasis
Purchase of Biopharmaceutical Company Will Boost Development of Nitroxyl-Based Cardiovascular Disease Drugs
Bacterial Curli Fibers Reverse Symptoms of Inflammatory Bowel Disease in Mouse Model
BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
