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BioResearch

Image: Cryoelectron micrograph reconstruction of the Chikungunya virus (Photo courtesy of the Washington University School of Medicine).

Broadly Neutralizing Antibodies Protect Mice from Alphavirus Infection

While screening a panel of mouse and human monoclonal antibodies that had been raised against Chikungunya virus, researchers identified several with inhibitory activity against multiple other arthritogenic alphaviruses.  More...
24 Nov 2015

Molecular Light Shed on “Dark” Cellular Receptors

Scientists have created a new research tool to help find homes for orphan cell-surface receptors, toward better understanding of cell signaling, developing new therapeutics, and determining causes of drug side-effects.  More...
24 Nov 2015
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New Bioreactor System Streamlines Strain Screening and Culture

Biotechnology laboratories working with bacterial cultures will benefit from a new automated micro bioreactor system that was designed to enhance microbial strain screening processes.  More...
23 Nov 2015

Novel Molecular Signaling Pathway Inhibits Lung Cancer Growth and Metastasis

A gene that had not been linked previously to lung cancer was found to be a critical component of a novel molecular signaling pathway that restricts lung cancer progression and metastasis.  More...
23 Nov 2015
Image: Micrograph of the Gram-positive bacillus C. sporogenes (Photo courtesy of the University of Pennsylvania).

Inactivated Bacteria and Excreted Factors for Colorectal Cancer Treatment

Inactivated Clostridium sporogenes bacteria and medium harvested after growth of the bacteria were found to be potent inhibitors of colorectal cancer cells growing on two- and three-dimensional culture platforms.  More...
22 Nov 2015
Image: Ring structure of the RAD52 protein (Photo courtesy of Wikimedia Commons).

Potential Drug Candidate Blocks Alternate DNA Repair Route in BRCA-Mutated Cancer Cells

Cancer researchers have identified a low molecular weight compound that inhibits the RAD52 DNA repair protein and kills cancer cells with a BRCA mutation by blocking the alternate DNA repair route.  More...
22 Nov 2015
Image: S. islandicus being grown in laboratory mass culture (Photo courtesy of the University of Southern Denmark).

Thermophilic Archaeal Lipids Stabilize Drug-Delivery Liposomes

The possibility of using lipids extracted from microorganisms adapted to living in conditions of extreme heat and acidity to form liposomes for oral drug-delivery, which would able to survive passage through the harsh conditions of the stomach, was discussed in a recent paper.  More...
18 Nov 2015
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.