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BioResearch

Image: Micrograph of a cell carrying an RNA-targeted Cas9 system that reveals beta-actin mRNA distribution in the cytoplasm (Photo courtesy of the University of California, San Diego).

Advanced Gene Editing Technology Enables RNA Tracking in Living Cells

Genomics researchers have used a modified version of the CRISPR/Cas9 gene editing technique to track the movement of RNA in living cells.  More...
30 Mar 2016
Image: A confocal micrograph of the lesion core following spinal cord injury. Nuclear EdU (red) shows the presence of newly differentiated cells which produce Schwann cell myelin (green). These peripheral-like Schwann cells remyelinate central axons in the injured spinal cord and are important for spontaneous repair and functional recovery after spinal cord injury (Photo courtesy of King\'s College London).

Molecular Mechanism Regulating Regeneration of Spinal Nerves Identified

The protein neuregulin-1 was found to regulate the repair mechanism that attempts to restore lost myelin following spinal cord injury.  More...
29 Mar 2016
Image: A haploid cell with 23 chromosomes (left), and a diploid cell with 46 chromosomes (right) (Photo courtesy of Columbia University /The Hebrew University of Jerusalem).

Novel Haploid Stem Cells Expected to Advance Genomics Research

A team of cell biologists has generated a novel type of haploid pluripotent embryonic stem cells that have only one set of chromosomes instead of the usual two.  More...
29 Mar 2016

Collaborative Agreement Focuses on Development of Small-Molecule Therapeutics for Leukemia and Other Cancers

A collaborative agreement between a renowned American university-based research institute and one of the largest pharmaceutical companies in the world will focus on the development of small-molecule therapeutics for leukemia and other cancers.  More...
28 Mar 2016
Image: A scanning electron microscopic (SEM) image of the microneedle-array beta-cell patch (Photo courtesy of Dr. Zhen Gu, University of North Carolina).

Microneedle Delivery of Beta-Cells Avoids Host Immune Rejection

A novel skin patch filled with living insulin-secreting beta cells was shown to regulate glucose levels in a mouse diabetes model for up to 10 hours while avoiding adverse immune responses.  More...
28 Mar 2016
Image: The iNPG drug delivery process (Photo courtesy of Houston Methodist Research Institute).

Nanoparticle Drug Delivery Avoids Cancer Cells' Protein Pumps

A novel nanoparticle delivery system avoids excretion by cancer cells' protein pumps and transports the highly toxic anti-cancer drug doxorubicin directly into the nuclei of cancer cells without causing damage to normal tissues or cells.  More...
27 Mar 2016
Image: Reprogrammed human neurons grown on 3D scaffolds (within the white dash line) and transplanted onto brain tissue (red) extended out (yellow lines) and integrated (Photo courtesy of Neal K. Bennett, Moghe Laboratory, Rutgers University).

3D Network Structures Improve Survival of Transplanted Stem Cell-Derived Neurons

Neurological disease researchers have developed a method for treating neurodegenerative diseases such as Parkinson's by transplanting three-dimensional networks of stem cell-derived neurons into the damaged brain tissue.  More...
27 Mar 2016
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.