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Pathology

Imaging and Blood Test Work Together to Optimize Evaluation of Ovarian Cancer Risk

A new US Food and Drug Administration-cleared blood test that measures the levels of five proteins and then uses a proprietary algorithm and software to calculate a single risk score has been the topic of recent research comparing the test to two imaging modalities.  More...
15 Apr 2014
Image: Molecule model of calreticulin (Photo courtesy of Wikimedia Comons).

American Diagnostic Laboratory Offers Genetic Test for Calreticlin Gene Mutations

A new diagnostic test that detects mutations in the gene encoding for the protein calreticulin is expected to help physicians identify patients with certain types of myeloproliferative neoplasms, which are blood cancers that have the potential to evolve into acute leukemia.  More...
14 Apr 2014
Image: Melanoma on a patient\'s skin (Photo courtesy of the [US] National Cancer Institute).

A Specific Mutation Links Some Forms of Inherited Melanoma

A mutation that inactivates the POT1 gene has been linked to the development of an inherited form of melanoma.  More...
09 Apr 2014
Image: The concentration of biological molecules in a sample can be observed visually using laser-stimulated fluorescence (Photo courtesy of Fraunhofer IPA).

Blood Test Detects Tumor Markers Using Laser-Stimulated Fluorescence

Tumor markers in the blood help determine whether the patient is afflicted with a malign tumor and whether it is excreting markers more vigorously involving highly specific proteins.  More...
09 Apr 2014
Image: Histopathology of small cell carcinoma of the ovary, hypercalcemic type; the tumor cells are arranged in small nests (Photo courtesy of Dr. Dharam Ramnani).

Genetic Cause Found for Rare Aggressive Ovarian Cancer

The genetic cause of a rare type of ovarian cancer known as small cell carcinoma of the ovary, hypercalcemic type, that most often strikes girls and young women has been revealed.  More...
09 Apr 2014
Image: The LTQ-FT Orbitrap XL Hybrid Ion Trap Mass Spectrometer (Photo courtesy of Thermo Scientific).

Proteomic Methods Diagnose Pancreatic Cancer

A method has been developed that identifies pancreatic cancer's visible precursors with 97% certainty, and is expected to aid in the early discovery of the cancer as well as minimize the risk of unnecessary surgery.    More...
08 Apr 2014

Gene Profile Predicts Risk of Bladder Cancer Recurrence

A genomic study has pinpointed several markers that identify bladder cancer patients at risk of recurrence and that may be indicators of overall survival status.  More...
07 Apr 2014
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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