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Pathology

Image: University of Louisville investigators noted that plasma thermograms have different patterns associated with different demographics, as well as for different diseases (Photo courtesy of the University of Louisville).

Use of Noninvasive Blood Thermograms to Diagnose Cervical Cancer

Differential scanning calorimetry, a noninvasive analytical tool, has been adapted to analyze blood samples and produce plasma thermograms that are diagnostic for cervical cancer.   More...
22 Jan 2014

MicroRNAs Predict Likelihood of Breast Cancer Metastasis

The discovery that breast cancer patients who experienced quick relapses tended to have low levels of the microRNA miR-21 and high levels of the microRNA miR-205 in their tumor tissues suggests that measurement of these two biomarkers could identify women at risk of metastasis.  More...
22 Jan 2014
Image: The Nanodrop 1000 Spectrophotometer (Photo courtesy of Thermo Fisher Scientific).

Blood Test Locates Gene Defects Linked to Cancer

A simple blood test could be developed to determine whether gene mutations associated with pancreatic cancer exist without the need of locating and testing tumor tissue.  More...
21 Jan 2014

Determination of Circulating CPN Cleavage Peptides Enables Early Diagnosis of Breast Cancer

The concentration of circulating peptides produced by CPN cleavage reflects the CPN activity in tumors, and analysis of these biomarkers demonstrates potential for the noninvasive and early diagnosis of breast cancer.  More...
20 Jan 2014
Image: MammaPrint, a prognostic 70-gene profile for early-stage breast cancer (Photo courtesy of Agendia).

Molecular Diagnostics Optimized for Breast Cancer Tissue Samples

A prognostic 70-gene profile assay for early-stage breast cancer has been available for fresh tissue, and improvements in ribonucleic acid processing have enabled microarray diagnostics for formalin-fixed, paraffin-embedded tissue.  More...
16 Jan 2014
Image: Pittsburgh Compound B (PiB) positron emission tomography scan of a patient with Alzheimer\'s disease (AD) on the left; red and yellow show high concentrations of PiB in the brain and suggest high amounts of amyloid deposits in these areas (Photo courtesy of the University of Pittsburgh).

Serum Cholesterol Levels Linked to Cerebral Amyloidosis

The relationship between elevated cholesterol and increased risk of Alzheimer’s disease has been specifically linked to amyloid deposits in living human study participants.   More...
15 Jan 2014
Image: The Illumina Genome analyzer (Photo courtesy of Illumina).

Cervical Cancer Genomic Study Completed

A comprehensive genomic analysis of cervical cancer in two patient populations has been completed and recurrent genetic mutations have been identified not previously found in cervical cancer.  More...
14 Jan 2014
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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