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Pathology

Image: Example of chromosomes stained with the FHACT combination probe: 3q26 (TERC) (red), 5p15 (D5S2095) (green), 20q13 (D20S911) (gold), and CEP7 (aqua) (Photo courtesy of Cancer Genetics Inc.).

Cervical Cancer Screening Test Receives Approval for the European Sector

A screening test that detects the clonal chromosomal aberrations commonly found in cervical cancer specimens has received CE-marking that allows it to be distributed as a diagnostic test in the 28 countries making up the European Economic Area.  More...
09 Sep 2014

Bladder Cancer Risk Predicted by Low Levels of Blood in the Urine

Blood in the urine, whether visible to the naked eye or not, is an early warning sign for the development of bladder cancer.  More...
08 Sep 2014
Image: The FDA-approved Cologuard test – a noninvasive, stool-based DNA colorectal cancer screening test (Photo courtesy of Exact Sciences).

US FDA Approves Noninvasive DNA Colorectal Cancer Screening Test

The first stool-based colorectal screening test that detects the presence of red blood cells and DNA mutations has been officially approved.  More...
03 Sep 2014
Image: Histopathology of a hepatoblastoma, a type of liver cancer found in infants and young children (Photo courtesy of Nephron).

Gene Identified That Promotes Childhood Cancers

A gene has been identified that contributes to the development of several childhood cancers and this could lead to new strategies for targeting certain childhood cancers at a molecular level.   More...
03 Sep 2014
Image: The microfluidic device : as cells undergoing the epithelial-mesenchymal transition move from left to right through the EMT chip, those expressing mesenchymal markers (red) break away and move independently from other cells, while cells expressing epithelial markers (green) continue to move as a collective front (Photo courtesy of Massachusetts General Hospital).

Microfluidic Device Monitors Key Step in Development of Tumor Metastases

A device has been developed that may help study key steps in the process by which cancer cells break off from a primary tumor to invade other tissues and form metastases.  More...
03 Sep 2014
Image: Histopathology of increased endomysial connective tissue from a patient with Duchenne Muscular Dystrophy. Necrotic fibers arrowed (Photo courtesy of Washington University in St. Louis).

New Partnership Designed to Automate Dystrophin Measurement

A developer of innovative ribonucleic acid-based therapeutics, Sarepta Therapeutics, and a leading tissue-based companion diagnostics firm, Flagship Biosciences announced a multiyear, multiproduct partnership.  More...
31 Aug 2014

Biomarker for an Aggressive Breast Cancer Identified

Using bioinformatics, scientists have identified an overactive transcription factor strongly associated with basal-like breast carcinoma—providing a biomarker with potential for improved diagnostics and as a smart target for new therapeutics for patients with this highly aggressive, often chemotherapy-resistant cancer.  More...
31 Aug 2014
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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