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Pathology

Image: Histopathology of pancreatic adenocarcinoma arising in the pancreas head region (Photo courtesy of Dr. KGH/Wikimedia).

Multiple Genetic Changes Linked to Increased Pancreatic Cancer Risk

A genome-wide association study, believed to be the largest of its kind, has uncovered four regions in the human genome where changes may increase the risk of pancreatic cancer.   More...
06 Jul 2015
Image: Histopathology of a benign sub-pleural lung nodule showing spindle cell lesion morphology (Photo courtesy of Aga Khan University Hospital).

Molecular Blood Test Helps Physicians Identify Benign Lung Nodules

Conservative management of lung nodules, sometimes referred to as watchful waiting, involves repeated computerized tomography scans over a two-year period to monitor the progress of patients whose nodules are initially deemed likely to be benign.  More...
05 Jul 2015
Image: A Selected-Ion Flow-Tube Mass Spectrometry Instrument for measuring chemical compounds in exhaled breath (Photo courtesy of Keele University).

Breath Test Developed to Diagnose Esophageal and Gastric Cancer

A breath test has been devised that can help doctors diagnose the early signs of esophageal and gastric cancer in minutes and the test can discriminate between malignant and benign esophageal cancer in patients for the first time.  More...
05 Jul 2015
Image: The droplet-based surface sampling probe, a newly developed mass spectrometry-based technology, speeds the process of analyzing a cancer patient liver biopsy sample (Photo courtesy of Oak Ridge National Laboratory).

New Diagnostic Tool on Horizon for Surgeons Treating Cancer Patients

Researchers have successfully developed a new tool that may enable surgeons to determine if a biopsy tissue is cancerous while their patients are still on the operating table, without routinely requiring microscope-based pathology analysis of the tissue.   More...
05 Jul 2015
Image: Histopathology of an adenocarcinoma of the colon in which the glands are enlarged and filled with necrotic debris (Photo courtesy of Dr. Charanjeet Singh, MD).

Biomarkers Help Personalize Metastatic Colorectal Cancer Treatment

In patients with metastatic colon cancer, response to first line chemotherapy is a strong predictor of overall survival, but currently, oncologists lack diagnostic tests to determine which chemotherapy regimen offers the greatest chance for response in an individual patient.  More...
29 Jun 2015
Image: Histopathology of an oligodendroglioma showing the characteristic branching, small, chicken wire-like blood vessels and fried egg-like cells, with clear cytoplasm and well-defined cell borders (Photo courtesy of Nephron).

Molecular Classification Improves Method to Diagnose Gliomas

The molecular makeup of brain tumors can be used to sort patients with gliomas into five categories, each with different clinical features and outcomes.   More...
28 Jun 2015
Image: The INNO-BIA Alzbio3 multiparameter immunoassay allows the simultaneous quantification of Aß1-42, total tau, and P-tau181P in cerebrospinal fluid (CSF) using xMAP technology (Photo courtesy of Fujirebio Europe N.V.).

Specialized Proteins Detected In Blood of Alzheimer's Disease Patients

In a select group of people who later developed dementia, the levels of the lysosomal proteins were abnormal while the people still had no problems with memory or thinking skills.  More...
28 Jun 2015
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.