Pathology

Gene Mapping Reveals Mutation in Myeloma Patients Linked to High Risk of Treatment Failure

Gene mapping of patients suffering from myeloma has enabled the identification of a genetic signature linked to the likelihood of the disease becoming more genetically complex and more likely to evolve into treatment-resistant forms. More...
04 May 2015

Image: The Avance III 600 spectrometer for proton nuclear magnetic resonance analysis (Photo courtesy of Bruker).

New Blood Test Can Predict Future Breast Cancer

The analysis of a blood sample could predict if a woman will get breast cancer within two to five years which could create a paradigm shift in early diagnosis of this malignant neoplasm as well as other diseases. More...
29 Apr 2015

Simple Assay Determines Lymphoma Subtypes Rapidly

Diffuse large B-cell lymphoma, the most common non-Hodgkin lymphoma, is subdivided into germinal center B-cell-like and activated B-cell-like subtypes, but these lymphomas are difficult to discriminate in routine diagnosis, impeding the development of treatments. More...
28 Apr 2015

Image: Gas chromatography linked to mass spectrometry apparatus (Photo courtesy of the Hebrew University).

Gastric Cancer Detected Through Exhaled Breath

A new type of technology that senses minute changes in the levels of particular compounds in exhaled breath accurately identifies high risk changes which herald the development of stomach cancer. More...
27 Apr 2015

Gene Involved In Hereditary Neuroendocrine Tumors Identified

To date, 11 main genes whose mutations are responsible for pheochromocytomas and paragangliomas have been identified and of these, 6 are involved in cellular metabolism, more specifically, the Krebs cycle, which is the machinery used by cells to burn oxygen and obtain the energy required for cellular work. More...
21 Apr 2015

Prostate Cancer Biomarker Gives Warning of Treatment Failure

A blood test that measures the number of cells shed from prostate tumors into the bloodstream can act as an early warning sign that treatment is not working. More...
15 Apr 2015

$Image: Breast tissue computationally stained using data from infrared imaging without actually staining the tissue, enabling multiple stains on the same sample. From left, the image shows a Hematoxylin and Eosin stain (pink-blue), molecular staining for epithelial cells (brown color) and Masson\'s trichrome (blue, red at right) (Photo courtesy of Prof. Rohit Bhargava).$