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Pathology

Image: The Qubit 3.0 Fluorometer (Photo courtesy of Life Technologies).

Mutated Gene Biomarker Identified for Rare Adrenal Tumors

A mutation in a gene has been found that may serve as a biomarker for the rare adrenal tumors pheochromocytomas and paragangliomas that become malignant.  More...
03 Feb 2015

Collaboration Agreement Targets Tumor-Related Genes

A German biomedical company has entered into a collaborative agreement with a major Norwegian hospital that focuses on the identification of cancer-related tumor genes that predict a patient’s response or resistance to targeted therapies.  More...
02 Feb 2015
Image: Electron microscope image of a harmful neutrophil (Photo courtesy of the Hebrew University of Jerusalem).

Neutrophil Subtypes Play Different Roles During Cancer Development

Evidence presented in a recent paper suggests that the role of neutrophils in tumor biology may need to be reconsidered. More...
01 Feb 2015
Image: Micrograph of a phyllodes tumor (right of image) with the characteristic long clefts and myxoid cellular stroma. Normal breast and fibrocystic change are also seen (left of image) (Photo courtesy of Wikimedia Commons).

Biomarker Panel Characterizes Rare Phyllodes Breast Tumors

Cancer researchers have established a panel of biomarkers that characterizes the rare phyllodes form of breast tumors.  More...
27 Jan 2015
Image: Illustration of a normal heart compared to a heart with dilated cardiomyopathy (Photo courtesy of Blausen Gallery 2014. Wikiversity Journal of Medicine).

Sequencing Study Links Mutations in Major Heart Muscle Protein to Development of Dilated Cardiomyopathy

British heart disease researchers using advanced gene sequencing techniques have identified mutations in the TTN gene, which encodes the muscle protein titin, linked to development of dilated cardiomyopathy that are different from benign mutations in this gene that are carried by a large percentage of the population.  More...
26 Jan 2015
Image: The ABI 7500 HT real-time polymerase chain reaction system (Photo courtesy of Applied Biosystems).

New Gene Identified That Drives Triple-Negative Breast Cancer

A novel gene has been discovered that, when mutated, can drive development and progression of triple-negative breast cancer which is an aggressive form of the disease that accounts for 10% to 20% of breast cancers.  More...
25 Jan 2015
Image: Schematics of the basis of the NuQ assays: A nucleosome is a section of DNA that is wrapped around a core of proteins. DNA is compacted as protein complexes in a “beads on a string” structure (Photo courtesy of VolitionRx Limited).

Blood Test Detects Early Stage Treatable Pancreatic Cancers

A recent clinical study has demonstrated that a blood-based diagnostic platform is able to accurately detect 84% of early, surgically-treatable pancreatic cancers with a high 92% specificity.   More...
20 Jan 2015
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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