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Pathology

Image: Inhibitor of differentiation 4 positive (ID4+) stem cells are in red, luminal cells in green, and all cells are marked with blue nuclear dye (Photo courtesy of Garvan Institute of Medical Research).

Gene Identified That Drives Aggressive Form of Breast Cancer

A gene has been identified that drives one of the most aggressive forms of breast cancer, giving hope that by finding a way to block the gene they may be able to make the cancer less aggressive.  More...
12 Apr 2015
Image: Histopathology of cribriform type ductal carcinoma in situ (DCIS) of the breast (Photo courtesy of Difu Wu).

Diagnostic Accuracy of Pathologists Interpreting Breast Biopsies Examined

Nearly one-quarter of breast biopsies demonstrate invasive breast cancer, the majority are categorized by pathologists according to a diagnostic spectrum ranging from benign to pre-invasive disease.   More...
06 Apr 2015
Image: The Automated Immunohistochemistry XT slide staining system (Photo courtesy of Ventana Medical Systems).

Prognostic Marker Identified for Head and Neck Squamous Cell Carcinoma

Molecular profiling may be useful for early diagnosis and treatment decisions for head and neck squamous cell carcinomas.   More...
05 Apr 2015

Biomarkers Differentiate Mild Brain Trauma from Other Types of Injury

A panel of protein biomarkers has been established that can identify patients with mild traumatic brain injury and differentiate those patients from healthy individuals and from patients with other injuries including broken bones.  More...
05 Apr 2015
Image: Histologic section of a colonic adenoma containing invasive carcinoma (Photo courtesy of Dr. Mauro Risio).

Blood Test Replaces Surgery for Bowel Cancer Tumor Determination

A blood test has been developed that could spare patients the stress of having tissue removed via biopsies for cancer diagnosis and to make the targeted use of therapy easier.  More...
01 Apr 2015
Image: Partial wave spectroscopy (PWS) is able to detect subtle changes in cells that indicate cancer growth in a different area of the body, even when those same cells appear normal under a microscope (Photo courtesy of North Western University).

Nanotechnology Accurately Predicts Prostate Cancer and Prognosis

The emerging field of nanocytology, using partial wave spectroscopic microscopy, could help men make better decisions about whether or not to undergo aggressive prostate cancer treatments.   More...
31 Mar 2015
Image: Micrograph of ALL cells. Relapse of the disease following chemotherapy was found to be due to mutations in minor subclones (Photo courtesy of St. Jude Children\'s Research Hospital).

Mutations in Minor Subclones Lead to Leukemia Relapse After Chemotherapy

Cancer researchers monitored changes in the genomic composition of acute lymphoblastic leukemia cells in all stages of cancer progression in order to determine why some cells survived chemotherapy to proliferate and eventually cause the death of the patient.  More...
30 Mar 2015
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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