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Pathology

Image: A cell phone camera is sufficient to examine tissue samples for tumor cells (Photo courtesy of Fraunhofer IAP).

Polymer-Based Rapid Test Visually Differentiates Tumor Cells

A polymer-based rapid test has been developed which visually differentiates tumor cells from healthy cells in a tissue section through the use of a simple microscope. Surgeons can already use the test in the operating room which saves time and expenses.  More...
18 Jan 2016
Image: (a) Interferogram obtained using IPM. Sample is still barely seen. However, the OPD information is encoded into the bend of the interference fringes, as can be seen from the enlarged region of interest in (b). (c) The OPD map of the same sperm cell, as digitally calculated from the interferogram shown in (a). All the main morphological features of the cell are discernable. (c, e) Imaging of a sperm cell with an acrosomal vacuole, using: (d) label-based BFM, and (e) label-free IPM. The vacuole is clearly seen as a defect in the OPD map of the IPM image. BFM = bright-field microscopy; IPM = interferometric phase microscopy; OPD = optical path delay (Photo courtesy of Haifler M, Girshovitz P, et al., 2015, and Elsevier publications).

Improved Microscopy May Identify Best Viable Sperm Cells for Reproductive Assistance

Researchers’ cutting-edge, stain-free innovation enables more effective screening for and identification of high-quality sperm candidates for assisted reproductive technology.  More...
17 Jan 2016
Image: The Leica TCS SP8 confocal laser scanning microscope (Photo courtesy of Leica Microsystems Inc.).

Molecular Studies of Suppressor Gene Advance Understanding of Metastasis

A gene that is known to suppress the growth and spread of many types of cancer has the opposite effect in some forms of colorectal cancer and these findings may lay the foundation for new colorectal cancer treatments.  More...
17 Jan 2016
Image: Micrograph of prostatic adenocarcinoma with perineural invasion, conventional (acinar) type, the most common form of prostate cancer. Prostate biopsy, H&E stain (Photo courtesy of Nephron and Wikimedia).

Reduced PSA Screening May Delay Treatment for Earlier Onset Prostate Cancers

The number of prostate needle biopsies has been reduced and patients who do undergo the procedure are significantly more likely to be diagnosed with high risk disease, suggesting that over-diagnosis and overtreatment may have been reduced.  More...
13 Jan 2016
Image: The Salivette collection device for saliva samples (Photo courtesy of Sarstedt Ltd.).

Antibody Levels in Saliva Associated with Risk of Mortality

Immunoglobulins or antibodies are proteins secreted by white blood cells, which circulate in the body and tag, destroy, and/or neutralize bacteria, viruses, and other harmful or foreign materials, the antigens.   More...
05 Jan 2016
Image: Schematic diagram of the Liquid Biopsy platform LiqBiopSens concept (Photo courtesy of AWSensors).

High-Sensitivity Molecular Detection System Used in Cancer Screening

The current go-to method for reliable cancer diagnosis is tumor tissue biopsy, but this method is invasive, painful and expensive and it also only provides information of a single point in the evolution of the disease.  More...
04 Jan 2016
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Immunomarker Expression Clarified for Thoracic Tumors

Comprehensive morphological and immunohistochemical subtyping of tumors is of growing importance for therapy selection and propelled the concept of a tumor-specific, individualized treatment.   More...
03 Jan 2016
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.