Pathology
Improved Colon Cancer Diagnosis with Multitargeted DNA Biomarker Test
A large-scale clinical study showed that a noninvasive test that detects several DNA biomarkers and blood in stool samples was significantly more sensitive than the currently used fecal immunochemical test for diagnosis of colorectal cancer. More...31 Mar 2014
Highly Specific Blood Test Detects Creutzfeldt-Jakob Disease
A preliminary study has indicated that a blood test for infection by the prion that causes vCJD has sufficient sensitivity and specificity to justify a large study comparing vCJD prevalence in the United Kingdom with a bovine spongiform encephalopathy-unexposed population. More...20 Mar 2014
Quantization of Leukocyte Subsets with DNA Methylation Microarrays
A novel microarray-based technique uses DNA methylation to simultaneously quantify multiple leukocyte subsets, enabling the investigation of immune modulations in both fresh blood samples and archived samples that previously could not be used for such analysis. More...20 Mar 2014
Bone Metabolism Biomarkers Predict Prostate Cancer Survival
Levels of biomarkers linked to bone metabolism are indicative of survival in patients with castration-resistant prostate cancer, and identify a small group of patients who can benefit from treatment with the investigational drug atrasentan. More...19 Mar 2014
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In Other News
New PCR Assay Detects Gene Rearrangements in Preserved Samples from Lung Cancer Patients
Combined Screening Suggested to Better Detect ALK Rearrangements in Samples from Non-Small-Cell Lung Cancer Patients
Rise in Blood Levels of Heart Muscle Protein an Early Diagnostic Marker for Cardiac Injury
Pathology Leaders Outline Principles for Patient Safety
Genetic Markers Found for Breast Cancer Brain Metastasis
Thyroid Lesions Examined by Scanning Acoustic Microscope
Genomic Assay Predicts Probability of Heart Transplant Rejection
Circulating Tumor DNA a Sensitive and Specific Cancer Biomarker
High Levels of Vascular Endothelial Growth Factor Mark Noncancerous Pancreatic Cysts
Whole-Genome Testing Helps Identify Breast Cancer Treatments
DNA Reference Samples Will Regularize Diagnosis of Rett Syndrome
Low Cost Device Helps Diagnose Pancreatic Cancer
New Service for Circulating Tumor Cell Analysis Now Available
Test Identifies Risk of Developing Lymphoma
Protein Test Improves Survival Prediction for Oropharyngeal Carcinoma
Mosaic Confocal Microscopy Technique Speeds Up Skin Cancer Surgery
Test Identifies Resistance to Chemotherapy in Esophageal Cancer Patients
Common Leukemia Induced by Single Mutation in Osteoblasts
Germline and Somatic Variants Analyzed in Ovarian Cancer
Analysis of Exosome Uptake May Lead to Simplified Bladder Cancer Diagnosis
Molecular Blood Test Detects Lung Cancer
A Panel of MicroRNA Biomarkers Augments CA19-9 for Early Diagnosis of Pancreatic Cancer
DNA-Enrichment Technology May Help Replace Biopsies for Cancer Mutation Testing
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.