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Pathology

Image: Confocal micrograph of immunohistochemically stained human glioblastoma (hGBM) cells (Photo courtesy of Olympus).

Cancer Detected by Dynamic Morphology Tracking on Aptamer-Grafted Surfaces

Cell motility is a phenomenon where cells move by protruding and contracting sections of the membrane that is a complex process performed through sophisticated balancing act between internal cytoskeleton structure and the cell membrane proteins.  More...
22 Dec 2015
Image: Immunohistochemistry of estrogen receptor (ER)-positive (brown), in metastatic breast cancer (Photo courtesy of Dr. Steven Halls).

Different Mutations May Predict Different Responses to Chemotherapy

Among patients with estrogen receptor-positive, metastatic breast cancer, those who had a D538G and/or a Y537S mutation in the estrogen receptor 1 gene, as detected in cell-free DNA obtained from patient blood samples, had significantly worse median overall survival.  More...
21 Dec 2015

Advanced Digital Pathology System Enters Service in the United Kingdom

A major British hospital has incorporated an advanced digital pathology system, which is expected to increase diagnostic accuracy as well as streamlining the performance of the pathology department.  More...
20 Dec 2015
Image: The Olympus Fluoview confocal microscope (Photo courtesy of National University of Singapore).

Culture of Cancer Cells Predicts Response to Therapy

Circulating tumor cells are considered as surrogate markers for prognosticating and evaluating patient treatment responses and a novel technique has been developed to efficiently culture clusters containing circulating tumor cells in 14 days.  More...
16 Dec 2015
Image: Schematic illustration of the components of the parallel microfiltration system (Photo courtesy of University of California).

New Method Designed to Screen Cancer Cells

A screening method has been developed that utilizes viscoelastic characteristics to classify many more different types of cancer cells and that could ultimately lead to better treatments for a variety of other diseases.  More...
15 Dec 2015
Image: Histopathology of non-small-cell lung cancer (Photo courtesy of the Center of Genome Pathology).

Biomarker of Early-Stage Lung Cancer Identified

A biomarker that detects the most common lung cancer in its earliest stage has been identified and this discovery could one day change how long lung cancer patients live.  More...
15 Dec 2015
Image: Histopathology of urothelial carcinoma of the urinary bladder from a transurethral biopsy (Photo courtesy of KGH/Wikipedia).

Tumor Sample Purity May Significantly Bias Genomic Analyses

The proportion of normal cells, especially immune cells, intermixed with cancerous cells in a given tissue sample may significantly skew the results of genetic analyses and other tests performed by physicians selecting precision therapies.   More...
15 Dec 2015
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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