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Pathology

Image: The cantilever on the left bears the recognition sequence for the target mutation. If this is present in the sample being tested, the corresponding segment of RNA binds to the cantilever, causing the latter to bend. This can be measured, providing clear evidence that the genetic change is present (Photo courtesy of the University of Basel, Department of Physics).

Microcantilever-Based Sensor Detects BRAF-Mutated Malignant Melanoma

A novel nanosenor comprising minute cantilevers labeled with malignant melanoma-derived RNA enabled identification of patients with the BRAFV600E mutated form of the disease in less than 24 hours. More...
19 Sep 2016
Image: The BMG OPTIMA FLUOstar plate reader (Photo courtesy of BMG LABTECH).

Early Parkinson's Diagnosis Moves Closer with New Protein Test

There is currently no definitive test for Parkinson's and the disease is normally diagnosed through assessment of the patient's medical history, a medical examination, and physical and neurological tests, but this can take years. More...
15 Sep 2016
Image: The BD LSRII flow cytometer (Photo courtesy of Becton Dickinson).

Circulating Immune Cells Act As Idiopathic Pulmonary Fibrosis Biomarkers

Patients with fibrotic lung diseases, such as idiopathic pulmonary fibrosis (IPF), show progressive worsening of lung function with increased shortness of breath and dry cough. More...
14 Sep 2016
Image: The QX200 Droplet Digital Polymerase Chain reaction  (ddPCR) system (Photo courtesy of Bio-Rad).

Blood Test Detects New Breast Cancer Subtype

A blood test has been developed that detects when the most common form of breast cancer has become resistant to treatment could double the average time it takes for the disease to progress, from around two and a half to around six months. More...
14 Sep 2016
Image: Researchers have made a significant step towards the development of a simple blood test to predict the onset of Alzheimer’s disease (Photo courtesy of Cardiff University).

Proteins Predict Alzheimer's Disease Risk in Patients with Mild Cognitive Disorder

A blood test that measures a panel of three complement proteins was shown to predict which individuals with a mild cognitive disorder would most likely progress to develop Alzheimer's disease (AD). More...
12 Sep 2016
Image: A photomicrograph of a leukemic cell and an extracellular vesicle (Photo courtesy of University of Manchester).

Novel Leukemic Blood Test Has Massive Diagnostic Potential

The potential of a new test, which could revolutionize the way doctors diagnose and monitor common childhood leukemia, has been explored. The test is based on the fact that cancerous acute lymphoblastic leukemia cells produce and release special structures that can be traced in the blood. More...
07 Sep 2016
Image: A malignant melanoma on a patient’s skin (Photo courtesy of the National Cancer Institute).

Immune Analysis of Biopsies Predicts Response to Melanoma Immunotherapy

Immune response measured in tumor biopsies during the course of early treatment predicts which melanoma patients will benefit from specific immune checkpoint blockade drugs. More...
01 Sep 2016
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.