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Pathology

Image: The ABI 7900HT Fast Real-Time Polymerase Chain Reaction (PCR) System (Photo courtesy of Applied Biosystems).

Blood Test Gives Early Warning of Melanoma Relapse

Targeted immunotherapies have transformed melanoma care, extending median survival from around 9 to over 25 months but nevertheless, most patients still die of their disease and although most melanoma patients respond to treatment at first, their cancer can become resistant within a year.   More...
21 Mar 2016
Image: The ScheBo Tumor M2-PK Stool sandwich enzyme-linked immunosorbent assay (Photo courtesy of ScheBo Biotech AG).

Enzyme Signpost Points to Better Bowel Cancer Test

A sensitive screening tool for colorectal cancer that detects a special isoenzyme of pyruvate kinase, termed M2-PK, which leaks from the cancerous tissue into the bowel, can then be found in feces.   More...
20 Mar 2016
Image: Close-up of the differential immuno-capture biochip (Photo courtesy of Dr. Umer Hassan, University of Illinois).

Novel Biochip Combines Antibody Binding and Electronic Counting to Simplify Diagnosis of HIV/AIDS

A recent paper described the construction of a microchip biosensor that uses immuno-capture technology to detect sub-populations of immune leukocytes.  More...
20 Mar 2016
Image: A stained frozen section slide used for the analysis while a patient is still on the operating table (Photo courtesy of the Mayo clinic).

Frozen Section Analysis for Breast Cancer Saves Time

When diagnosed with breast cancer, women may have thousands of questions running through their minds, but one they may not have immediately is: Will my choice of provider save me time and money?   More...
15 Mar 2016
Image: A cancer of the iris known as uveal melanoma (Photo courtesy of Dr. Jonathan Trobe, MD).

Biomarker Identifies Uveal Melanoma Patients at Risk for Metastasis

Uveal melanoma is a cancer of the eye involving the iris, ciliary body, or choroid, collectively referred to as the uvea. Tumors arise from the pigment cells that reside within the uvea giving color to the eye.   More...
15 Mar 2016
Image: Micrograph of microglia cells, which selectively express the TREM2 protein (Photo courtesy of Wikimedia Commons).

CSF Biomarker Elevated in Early Stages of Alzheimer's Disease

Elevated levels of the soluble form of the TREM2 immune receptor protein in cerebrospinal fluid have been linked to symptoms of early-stage Alzheimer's disease.  More...
13 Mar 2016
Image: Streptococcus mutans colonies growing on Mitis Salivarius Bacitracin agar showing convex, pale blue colonies with granular frosted glass appearance (Photo courtesy of Drs. Rajan and Shivani Dhawan).

Oral Bacteria Linked to Risk of Intracerebral Hemorrhage

Physicians have an increased understanding of patients entering the hospital for acute stroke, and the association between certain types of stroke and the presence of the oral bacteria centronuclear myopathies gene-positive Streptococcus mutans.  More...
09 Mar 2016
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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