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Pathology

Image: A micrograph of the target cells (green) sticking to the microarray platform (red) (Photo courtesy of Dr. Michael Hirtz / KIT).

Cancer Cells Detected Before They Form Metastases

A versatile microarray-based platform has been developed that is able to capture single target cells from large background populations as analyses of rare events occurring at extremely low frequencies in body fluids are still challenging.  More...
06 Dec 2015
Image: Ion OneTouch 2 System (Photo courtesy of Thermo Fisher).

Blood Test Detects When Breast Cancer Becomes Resistant to Treatment

A highly sensitive blood test has been developed that can spot when breast cancers become resistant to standard hormone treatment, and it has been demonstrated that this test could guide further treatment.    More...
02 Dec 2015
DIASOURCE (A Biovendor Company)
Image: Scanning electron micrograph of a clump of activated platelets (Photo courtesy of Brown University).

Blood-Based Platelet RNA Tests Detects Cancer

Cancer is primarily diagnosed by clinical presentation, radiology, biochemical tests, and pathological analysis of tumor tissue, increasingly supported by molecular diagnostic tests.  More...
01 Dec 2015
Image: Histopathology of meningeal carcinomatosis: tumor cell clusters in the subarachnoid space in a brain biopsy (Photo courtesy of Dr. Michael J. Schneck, MD).

Cerebrospinal Fluid Liquid Biopsy Characterizes Brain Tumors

The exploitation of cerebrospinal fluid-derived circulating DNA as liquid biopsy promises a more accurate, effective and less invasive approach in unmasking the molecular characteristics of brain tumors.  More...
23 Nov 2015
Image: The RainDrop droplet polymerase chain reaction system (Photo courtesy of RainDance Technologies).

DNA in Blood Tracks Cancer Development and Response

Circulating tumor DNA analysis can be used to track tumor burden and analyze cancer genomes noninvasively, but the extent to which it represents metastatic heterogeneity is unknown.  More...
23 Nov 2015
Image

Blood Samples Analysis Monitors Colorectal Cancer Chemotherapy Response

Circulating cell-free DNA may be collected from plasma of colorectal cancer patients and represents a less invasive, less costly approach to tracking biomarkers of interest longitudinally and at progression.  More...
18 Nov 2015
Image: The Cologuard multi-target stool DNA test kit (MT-sDNA) for colorectal cancer screening (Photo courtesy of Exact Sciences Corporation).

Screening Stool DNA Test Detects Colorectal Cancer

The accuracy of a multi-target stool DNA test compared with fecal immunochemical testing for hemoglobin for detection of screening-relevant colorectal neoplasia in Alaska Native people has been assessed.   More...
16 Nov 2015
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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