Pathology

Low-Frequency TP53 Gene Mutations Also Found in Healthy Women
Worldwide, more than 250,000 new cases of ovarian cancer are diagnosed each year, and two-thirds of these women die from the disease. This high mortality is largely due to the high frequency of metastasis before diagnosis and a lack of effective screening and early detection methods. More...19 Jul 2019

Blood Test Complements Colonoscopy for Lynch Syndrome Patients
Lynch syndrome (LS) subjects are genetically predisposed to a high risk for colorectal cancer (CRC) and regular colonoscopy is currently the only CRC screening option recommended for these subjects, although compliance is suboptimal. More...16 Jul 2019

Microbiome Composition Altered in Fibromyalgia Patients
Fibromyalgia (FM) is a prevalent syndrome, characterized by chronic widespread pain, fatigue and impaired sleep, that is challenging to diagnose and difficult to treat. FM is a long-term condition that affects 2% to 4% of the USA population, which equates to about 6 to 12 million people. More...11 Jul 2019

Protein Linked to Aggressive Skin Cancer
Almost 300,000 people worldwide develop malignant melanoma each year. The disease is the most serious form of skin cancer and the number of cases reported annually is increasing, making skin cancer one of Sweden's most common forms of cancer. More...10 Jul 2019

Test Determines If Cancer Patients Require Chemotherapy
Invasive lobular carcinoma (ILC) is the most common special type of breast cancer, and is characterized by functional loss of E-cadherin, resulting in cellular adhesion defects. ILC typically present as estrogen receptor positive, grade 2 breast cancers, with a good short-term prognosis. More...09 Jul 2019

Metastases May Form Early in Development of Colorectal Cancer
Colorectal cancer (CRC), also known as bowel cancer and colon cancer, is the development of cancer from the colon or rectum (parts of the large intestine). Signs and symptoms may include blood in the stool, a change in bowel movements, weight loss, and feeling tired all the time. More...04 Jul 2019

In Other News
New Genetic Link to Premenopausal Breast Cancer Discovered
New Biomarker Test Improves Diagnosis of Ovarian Cancer
Pathogenic Variant Carriers Missed by Current Genetic Testing
Identifying Colorectal Cancer Subtypes Improves Treatment Decisions
Masspec Pen Evaluated for Rapid Diagnosis of Cancer
Novel Methylated DNA Markers Assay Detects Cancer
Unhealthy Gut Promotes Spread of Breast Cancer
Rare Gut Bacteria Linked to Restless Legs Syndrome
Custom NanoString Assay Detects Bowel Cancer Subtypes
Microfluidic Motility Device Indicates Likelihood of Breast Tumor Metastasis
Genomic Analysis Uncovers Differences in Liver Cancer Subtypes
CtDNA Forecasts Non-Metastatic Colorectal Cancer Recurrence
Liquid Biopsy Identifies Mutations Predicting Ovarian Cancer Treatment Response
Technology Developed to Capture Tumor Cells
Urinary Biomarkers Diagnose Serious Kidney Allergic Reaction
Blood Test Measures Effectiveness of Aggressive Cancer Treatments
Genomic Data Affects Prognosis of Advanced Prostate Cancer
Assay Stratifies Esophageal Cancer Patients for Treatment
Protein Panel Accurately Differentiates Forms of Ovarian Tumors
Prostate Cancer Severity Indicated by Location and Concentration of Syntaphilin
Clinical Validation Bolsters Liquid Biopsy Evidence Base
Breast Cancer Test Determines Most Effective Treatment
Biomarker Predicts Appropriate Immunotherapy for Cancer Patients
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.