Pathology
Intraoperative Frozen Section Detect Acute Invasive Fungal Rhinosinusitis
Acute invasive fungal rhinosinusitis (AIFRS) is a potentially lethal and rapidly progressive disease. It primarily affects immunocompromised or diabetic patients, in whom organisms that are ubiquitous, but usually harmless can invade mucosa and rapidly disseminate to the orbit and cranial cavity. More...09 Jun 2021
Analytic Validation and Clinical Utilization of Comprehensive Genomic Profiling Test
Cancer has a high clinical burden and oncology therapies are expensive. It is estimated that 1,898,160 new cancer cases will be diagnosed and over 608,570 deaths are projected to occur in the USA in 2021. The prevalence of cancer is expected to rise over time, providing an expanding unmet need for genomic tests to help physicians treat patients in a more precise manner. More...02 Jun 2021
Colorectal Cancer Relapse Predicted by ctDNA Clearance
Colorectal cancer (CRC) is the third most common cancer around the world with more than 1.9 million new cases diagnosed annually. CRC is also the second leading cause of cancer-related deaths with a 5-year mortality rate of about 40%. More...01 Jun 2021
Jagged Ends of Urinary Cell-Free DNA Assessed in Bladder Cancer Detection
Bladder cancer is where a growth of abnormal tissue, known as a tumor, develops in the bladder lining. In some cases, the tumor spreads into the bladder muscle. The most common symptom of bladder cancer is blood in the urine, which is usually painless. More...27 May 2021
Jagged Ends of Urinary Cell-Free DNA Assessed in Bladder Cancer Detection
Bladder cancer is where a growth of abnormal tissue, known as a tumor, develops in the bladder lining. In some cases, the tumor spreads into the bladder muscle. The most common symptom of bladder cancer is blood in the urine, which is usually painless. More...24 May 2021
Loss of Function Mutations in GEMIN5 Cause a Neurodevelopmental Disorder
GEMIN5, an RNA-binding protein is essential for assembly of the survival motor neuron (SMN) protein complex and facilitates the formation of small nuclear ribonucleoproteins (snRNPs), the building blocks of spliceosomes. More...20 May 2021
Human Microbiota Flagellins Drive Adaptive Immune Responses in Crohn’s Disease
Crohn's disease and ulcerative colitis, another type of inflammatory bowel disease (IBD), are characterized by dysregulated adaptive immune responses to the microbiota in genetically susceptible individuals, but the human specificity of these responses had so far been largely undefined. More...20 May 2021
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In Other News
Rapid, Direct-to-Digital Prostate Biopsy Pathology Evaluated
Developed Immunoassay Predicts Benefits of Anti-PD-1 Therapy in NSCLC
Holographic Histopathology Enables Fast, Precise Diagnostics
Genetic Background and Clinicopathologic Features Established for Adult-Onset Nephronophthisis
African-American MS Patients Experience More Rapid B-Cell Repopulation
GPS Assay Associated with Long-Term Prostate Cancer Outcomes
New Genetic Factors Involved in Sudden Unexpected Death in Children
Altered Perivascular Fibroblast Activity Precedes ALS Disease Onset
RNA-Sequencing Predicts Immunotherapy Success in Bladder Cancer
Tissue Counterpart to Monoclonal B-Cell Lymphocytosis Characterized
Breast Cancer Histopathology Employs Infrared Spectroscopic Imaging
Coagulation Dysfunction and Infection Evaluated in Patients with AECOPD
Spatial Landscape of Lung Pathology Investigated During COVID-19 Progression
Leukocyte Epigenomics and Artificial Intelligence Predict Late-Onset Alzheimer’s Disease
Single-Cell Transcriptomic Analysis Traces Neuroblastomas to Developing Adrenal Neuroblasts
Whole-Genome Sequencing Aids Rare Disease Diagnosis
Calcitonin and Procalcitonin Immunoassays Investigated for Medullary Thyroid Carcinoma
Immune Cells in Cerebrospinal Fluid Predict Response to Immunotherapy
Pediatric Pancreatic Cancer Diagnosed From cfDNA Fragments in Urine
CSF Biomarker Flags Parkinson's Pathology Much Earlier
Five Genes Help Predict Lewy Body Dementia
Clinical Germline Testing Evaluated for Pediatric Cancer Patients
Genetic Risk of Inflammatory Bowel Disease Appears Distinct in African Americans
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
