Pathology

Super-Enhancer Induces Oncogenic Driver in Colorectal Carcinoma
The etiology of super-enhancer (SE) reprogramming in cancer is incompletely understood, but is widely attributed to cancer cell-intrinsic genomic alterations. Non-coding SE can become focally amplified in multiple malignancies. More...24 Oct 2022

Gene Expression Profiling of Mucinous Ovarian Tumors Identifies Prognosis Markers
Advanced stage mucinous ovarian tumors have poor chemotherapy response and prognosis and lack biomarkers to aid Stage I adjuvant treatment. Differentiating primary mucinous ovarian carcinoma (MOC) from gastrointestinal (GI) metastases to the ovary is also challenging due to phenotypic similarities. More...18 Oct 2022

Link Identified Between Mitochondria and Pancreatic Cancer Risk
Tumors invariably rewire their metabolism to promote cellular plasticity, adapt to ever-changing nutrient availability and acquire traits of aggressive disease, including metastatic competence. Cancer metabolism has long been equated with the preferential utilization of glycolysis by tumor cells even when oxygen is present. More...18 Oct 2022

World’s First Precision Medicine Test Predicts Progression to Esophageal Cancer in Patients with Barrett’s Esophagus
A new study has shown that a precision medicine test can significantly improve a physician’s accuracy in assessing the risk of progression to high-grade dysplasia (HGD) or EAC in patients diagnosed with BE. More...17 Oct 2022

Self-Teaching AI Algorithm Uses Pathology Images to Diagnose Rare Diseases
Researchers have developed a deep learning algorithm that can teach itself to learn features which can then be used to find similar cases in large pathology image repositories and has many potential applications, including identifying rare diseases. More...11 Oct 2022

Digital Pathology Solution Provides Truly Interoperable Platform to Streamline Workflow
Gestalt Diagnostics, Inc. (Spokane, WA, USA) has received CE-IVD marks for two of the main components of PathFlow. Both the PathFlow viewer and the proprietary, automated workflows now have European regulatory clearance for broad use in clinical, education, and research laboratories. More...11 Oct 2022

Novel Microfluidic qDBS-Sampling Technology Could Find Broader Use in Clinical Diagnosis
A new collaboration aims to accelerate method development for the implementation of a novel microfluidic quantitative dried blood spot (qDBS) sampling-based technology for clinical diagnostics in the US and globally. More...07 Oct 2022
In Other News
Synovial Fluid NGAL Accurately Diagnoses Prosthetic Joint Infection
CDH1 Overexpression Predicts Early-Stage Bladder Cancer
Longitudinal Laboratory Data Predicts Complication in Crohn’s Disease Patients
PD-L1 Expression Associated With Poorer Survival in Anal Squamous Cell Carcinoma
IL-1RA Antibodies in Myocarditis After SARS-CoV-2 Vaccination
Molecular Endometrial Cancer Test Developed
AI-Based Pathology Diagnosis Tool Detects Seven Types of Gastric Cancer
Breakthrough Method Diagnoses Parkinson’s from Skin Swabs in Three Minutes
Sakura Finetek Launches New Advanced Staining System
AI-Powered Pathology Platform Advances Diagnosis of Prostate, Breast and Gastric Cancer
First-in-Class AI Diagnostic Solutions Improve Patient Outcomes in Breast Cancer and Colorectal Cancer
African-Specific Molecular Taxonomy of Prostate Cancer Revealed
Revolutionary Whole-Slide Scanner Breaks Paradigm of High-Volume Scanning
Glypican-3 Is Associated With Impaired Outcome in Merkel Cell Carcinoma
AI Model Accurately Shows Presence and Location of Cancer in Pathological Images
Digital Pathology System Provides Exceptional Image Quality Within Seconds
AI Detects Parasite from Photos of Blood Samples Taken with Smartphone
Genetic Link Found Between Gut Disorders and Alzheimer's Disease
Digital Spatial Profiling Augments Pathology in Diagnosing Pulmonary Fibrosis
Non-Invasive Digital Diagnostic Test to Redefine Bladder Cancer Surveillance
DNA Copy Number Alterations Impact Melanoma Metastasis
World’s First Automated Tissue Grossing Platform Uses AI to Assess Specimens
New Tool Enables Direct Detection of HPV mRNA in FFPE Tissue Specimens
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.







