Pathology
Advanced Mass Spectrometry Could Provide Microscopic Clues to Beating Deadly Brain Tumors
Glioblastoma is one of the most difficult cancers, let alone diseases, to treat. Now, scientists have discovered that a critical new pathway to treating brain tumor might be found in the complex diversity within the tumor tissue. More...01 Nov 2022
AI-Based Staining Technique as Accurate as Traditional Histopathology in Assessing Breast Cancer Biomarker
Upon breast cancer diagnosis, the testing of HER2 – a protein that promotes cancer cell growth, is routinely carried out to help assess the cancer prognosis and make HER2-directed treatment plans. Researchers have now developed a computational staining approach powered by deep learning, which performs the HER2 staining without requiring any chemicals. More...28 Oct 2022
Super-Enhancer Induces Oncogenic Driver in Colorectal Carcinoma
The etiology of super-enhancer (SE) reprogramming in cancer is incompletely understood, but is widely attributed to cancer cell-intrinsic genomic alterations. Non-coding SE can become focally amplified in multiple malignancies. More...24 Oct 2022
Gene Expression Profiling of Mucinous Ovarian Tumors Identifies Prognosis Markers
Advanced stage mucinous ovarian tumors have poor chemotherapy response and prognosis and lack biomarkers to aid Stage I adjuvant treatment. Differentiating primary mucinous ovarian carcinoma (MOC) from gastrointestinal (GI) metastases to the ovary is also challenging due to phenotypic similarities. More...18 Oct 2022
Link Identified Between Mitochondria and Pancreatic Cancer Risk
Tumors invariably rewire their metabolism to promote cellular plasticity, adapt to ever-changing nutrient availability and acquire traits of aggressive disease, including metastatic competence. Cancer metabolism has long been equated with the preferential utilization of glycolysis by tumor cells even when oxygen is present. More...18 Oct 2022
World’s First Precision Medicine Test Predicts Progression to Esophageal Cancer in Patients with Barrett’s Esophagus
A new study has shown that a precision medicine test can significantly improve a physician’s accuracy in assessing the risk of progression to high-grade dysplasia (HGD) or EAC in patients diagnosed with BE. More...17 Oct 2022
Self-Teaching AI Algorithm Uses Pathology Images to Diagnose Rare Diseases
Researchers have developed a deep learning algorithm that can teach itself to learn features which can then be used to find similar cases in large pathology image repositories and has many potential applications, including identifying rare diseases. More...11 Oct 2022
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.