Pathology

Exome Sequencing Identified Pathogenic Variants in Cerebral Palsy Patients
Cerebral palsy (CP) is a group of permanent movement disorders that appear in early childhood. Signs and symptoms vary among people and over time. Often, symptoms include poor coordination, stiff muscles, weak muscles, and tremors. More...18 Feb 2021

Biomarkers Evaluate Kidney Injury in Cancer Patients
Immune checkpoint inhibitors (ICI) are monoclonal antibodies that can unleash the immune system by blocking surface molecules that serve as important breaks (or checkpoints) that mediate negative regulation of T cells. ICI have substantially improved the prognosis for patients with a wide range of malignancies. More...17 Feb 2021

Biomarker Predicts Pancreatic Cancer Patients’ Response to CD40 Immunotherapy
Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer and currently the third leading cause of cancer deaths in the USA. Despite the fact that it only accounts for about 3% of new cancer cases, it is responsible for more than 7% of all cancer deaths, and only10% of patients survive five years with the disease. More...17 Feb 2021

TAP1 Gene Polymorphisms Associated with Recurrent Respiratory Papillomatosis
Recurrent respiratory papillomatosis (RRP) is a respiratory tract disease that affects children and adults and is characterized by the recurrent proliferation of multiple papillomas. The proliferation of multiple papillomas within the airway in RRP primarily affects the larynx. More...09 Feb 2021


Liquid Biopsy Predicts Colon Cancer Relapse Months Earlier
Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, is the development of cancer from the colon or rectum (parts of the large intestine). Signs and symptoms may include blood in the stool, a change in bowel movements, weight loss, and fatigue. More...03 Feb 2021

In Other News
Proinflammatory T Cell Polarization Investigated in Early Knee Osteoarthritis
Alzheimer's Progression Tracked with Blood Biomarkers
Mismatch Repair/Microsatellite Instability Evaluated Using Cytology Effusion Specimens
Metastatic Gastric Cancer Outcomes Informed by Single-Cell Transcriptome Profiles
Alzheimer's Disease Subtypes Proposed from Brain Gene Expression Profiles
Common Brain Malformation Traced to Its Genetic Roots
Combination Urinary Biomarker Panel Detects Pancreatic Cancer Earlier
Multiplex Bead-Based Immunoassay Validated for Non-Invasive Bladder Cancer Detection
Single-Cell Transcriptome Links Gut Development, Pediatric Crohn's Disease
Rare Genetic Variants Can Contribute to Ischemic Heart Failure
Distinct Mutation Patterns Identified in Appendiceal Cancer
Circulating Tumor Cell Dynamics Predicts Cancer Prognosis
Flow Cytometry Employed in Diagnosing Male Urethritis
Gene Expression Signature Traces Nonalcoholic Fatty Liver Disease Progression
Triple FIT Surpasses Single Sigmoidoscopy in CRC Screening
HDL-Cholesterol Predicts Survival in Cirrhotic Patients with Gastrointestinal Bleeding
Specific Gut Bacterium Linked to Irritable Bowel Syndrome
Incretin Hormone Levels Linked to Arteriosclerosis
Mitoses Counted with Digital Pathology in Breast Phyllodes Tumors
Blood Biomarker Predicts Guillain-Barré Prognosis
COVID-19 Lung Damage Caused by Persistence of Abnormal Cells
Circulating Tumor Cell-Count Drives Therapy Choice for Breast Cancer
Metabolomics Profiles Associated with Diabetic Retinopathy
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.