Immunology
Serum α-L-Fucosidase Activity Measured for COVID-19 Infection
An unusual fucosylated LacdiNAc in the receptor-binding domains of the spike protein of COVID-19 has been observed. Reduced fucosylation was also found in a specific Fc domain of IgG antibodies in COVID-19 patients that enhanced the interactions with the activating FcγR, FcγRIIIa. More...22 Apr 2021
Urinary Heat Shock Protein 70 Evaluated in Chronic Prostatitis
Chronic prostatitis (CP) is a common, but a confusing urological disease that seriously affects men's lives and health and cannot be ignored. The incidence rate is increasing, and the disease is affecting younger men and long‐term prostatitis affects male sexual function. More...21 Apr 2021
Breath Test Determines Severity of Methylmalonic Acidemia Disease
Methylmalonic acidemia is a disorder in which the body cannot break down certain proteins and fats. The result is a buildup of a substance called methylmalonic acid in the blood. This condition is passed down through families and is one of several conditions called an "inborn error of metabolism." More...20 Apr 2021
Randox Discovery Diagnostic Analyzer Wins 2021 Red Dot Award for High Design Quality
Randox Laboratories’ (Crumlin, UK) Discovery, a diagnostic analyzer which can consolidate molecular and immunoassay testing on one compact benchtop platform, has received the 2021 Red Dot Award for High Design Quality. More...16 Apr 2021
T Cells Recognize Recent SARS-CoV-2 Variants
Due to the proofreading ability of the coronavirus (CoV) RNA-dependent RNA polymerase, the evolution of the global SARS-CoV-2 viral population during the current pandemic has been relatively constrained as compared to other endemic RNA viruses that do not possess this ability. More...15 Apr 2021
Type 1 Diabetes Onset Preceded by Gene Expression Changes
Type 1 diabetes (T1D) results from insufficient insulin production and is thought to result from an immune reaction against the body’s own pancreatic β cells. The exact cause of T1D remains unknown, although asymptomatic islet autoimmunity lasting from weeks to years before diagnosis raises the possibility of intervention before the onset of clinical disease. More...14 Apr 2021
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In Other News
Serious Infections Prevalent in ANCA-Associated Vasculitis
Immunoassay Developed for Quantitative Detection of Serum Interleukin‐6
Performance of Five Lipoprotein(a) Immunoassays Evaluated
Flow-Cytometric Expression of Endoglin Assessed in B-Acute Lymphoblastic Leukemia
Toxoplasmosis Immune Status in Pregnancy Determined by Immunochromatography Assay
Toxoplasmic Encephalitis in HIV Patients Detected in Urine
Paraproteins Identification Methods Compared for Monoclonal Gammopathies
Chemiluminescence Anti‐Müllerian Hormone Assay Performance Characterized
Cardiac Troponins Assessed for Acute Heart Failure
Biomarker Protein Investigated in Juvenile Idiopathic Arthritis
Immune Response to Insulin Identifies Risk of Juvenile-Diabetes
Fibrinogen to Albumin Ratio Reflects ANCA‐Associated Vasculitis Activity
Rh Alloimmunization Explored in Chronically Transfused Thalassemia Patients
Blood Biomarker Predicts Dementia in Cerebral Small Vessel Disease
Urinary Antigen Test Kit Evaluated for Diagnosing Legionella Pneumonia
Proteogenomic And Metabolomic Studies Characterize Human Glioblastoma
T Cell Response Profiled in COVID-19 Patients
Biomarker Predicts Pancreatic Cancer Patients’ Response to CD40 Immunotherapy
Blood Test Distinguishes Epileptic Seizures From PNES
TFP Inhibitor Levels Elevated in Bleeding Tendency Patients
New Control Mechanism Discovered in Innate Immune System
Prolonged Maternal Zika Viremia Evaluated for Adverse Perinatal Outcomes
Early Plasma Biomarkers Discovered for Alzheimer's Disease
The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.