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Immunology

Image: The dengue virus (DENV) Detect IgM Capture ELISA from InBios (Photo courtesy of Inbios).

First US FDA-Cleared Dengue Test Independently Evaluated for Detection Quality

Researchers have now reported results from a first evaluation of the FDA-cleared assay for diagnosis of dengue virus infection in patients with suggestive clinical symptoms. More...
16 Jul 2013

A Discrete Gene Signature Is a Diagnostic and Predictive Biomarker for Kidney Transplant Rejection

A genetic signature comprising two messenger RNA molecules that encode immune system proteins and one noncoding RNA molecule that participates in protein production has been shown to be diagnostic and prognostic of acute cellular rejection in kidney transplants. More...
15 Jul 2013
Image: Vertical Flow Rapid Diagnostic Test for Leptospirosis (Photo courtesy of Pasteur Institute of New Caledonia).

Serodiagnostic Test Developed for Human Leptospirosis

A vertical flow diagnostic test has been developed for the serodiagnosis of human leptospirosis, which is difficult to diagnose because of nonspecific symptoms and concurrent other endemic febrile diseases. More...
11 Jul 2013
Image: Kalazar Detect Test for Leishmaniasis (Photo courtesy of InBios International).

Blood Sampling Compared for Leishmaniasis Rapid Test

Antibody-detecting rapid diagnostic tests are available to aid in the diagnosis of visceral leishmaniasis, the second most fatal parasitic disease after malaria. More...
11 Jul 2013

Simplified Exome Mining Technique Identifies Mutated Antigens Recognized by Adoptively Transferred Tumor-Reactive T Cells

Cancer researchers have used advanced exome mapping technology to characterize mutated proteins expressed in patient tumors and then used peptides from these mutant proteins to isolate tumor-infiltrating lymphocytes suitable for therapeutic use. More...
09 Jul 2013

Immunohistochemistry as Effective as DNA Hybridization for Detecting ALK Rearrangement in Lung Cancer Patients

Researchers demonstrated that immunohistochemistry provided a reliable and cost-effective diagnostic approach in routine pathologic laboratories for the identification of patients with non-small-cell lung cancer. More...
08 Jul 2013
Image: Human pancreas stained with anti-glutamic acid decarboxylase 65 antibody (Photo courtesy of Mybiosource).

Blood Test Predicts Diabetes Mellitus Type 1 Risk

Type 1 diabetes usually has a preclinical phase identified by circulating islet autoantibodies, but the rate of progression to diabetes after seroconversion to islet autoantibodies is equivocal. More...
04 Jul 2013
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.