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Immunology

Image: A histopathology of Hepatitis C viral infection of the liver, necrosis and inflammation are prominent, and there is some steatosis (Photo courtesy of the University of Utah Medical School).

Novel Test Allows for One-Step Diagnosis of HCV Infection

The current standard in diagnosing Hepatitis C virus (HCV) infection requires two sequential steps that make it suboptimal, costly, inconvenient, time consuming, and globally not widely available or affordable. More...
21 Jun 2016
Image: New research suggests using an hs-CTrop-I assay can speed up diagnosis of a heart attack (Photo courtesy of Medscape).

New Blood Test Approach Helps Identify or Rule-Out Heart Attack

Two new studies have suggested that modified algorithms using the high-sensitivity cardiac troponin I (hs-CTrop-I) assay could help more quickly identify or exclude the diagnosis of a heart attack for patients reporting to an emergency department (ED) with suspected cardiac chest pain. More...
13 Jun 2016
Image: A strongly positive Mantoux tuberculin skin test (Photo courtesy of Mudnsky).

New Skin Test Developed For Tuberculosis Infection

A new skin test for tuberculosis infection has been tested and has proven safe, easy to administer and accurate in two Phase III clinical trials. The test is administered like a tuberculin skin test (TST), and results are interpreted by measuring the size of the skin induration two or three days later. More...
02 Jun 2016
Image: A model of the principle underlying the modified Ham test (Photo courtesy of Johns Hopkins University).

Blood Test Advances Diagnosis Of HELLP Syndrome

A laboratory blood test for the diagnosis of a rare genetic red blood cell disorder also shows promise in identifying HELLP syndrome, a life-threatening high blood pressure condition affecting 1% of all pregnant women. More...
01 Jun 2016
Image: The typical erythema migrans or bulls-eye rash often but not always seen in Lyme disease (Photo courtesy of the CDC).

Early-Detection Urine Test Is Effective for Lyme Disease

Prompt antibiotic treatment of early stage Lyme Borreliosis (LB) prevents progression to severe multisystem disease and there is a clinical need to improve the diagnostic specificity of early stage Lyme assays in the period prior to the mounting of a robust serology response. More...
01 Jun 2016
Image: The SD Bioline Dengue Duo Rapid Diagnostic Test (RDT) (Photo courtesy of Standard Diagnostics).

Dengue Rapid Diagnostic Tests Recycled For Serotyping

Dengue virus infection causes major public health problems in tropical and subtropical areas, but in many endemic areas, inadequate access to laboratory facilities is a major obstacle to surveillance and study of dengue epidemiology. More...
25 May 2016
Image: A micrograph of eosinophilic esophagitis (EoE), H&E stain. Characteristic features are present: Abundant eosinophils – criteria vary; one common definition is: > 20 eosinophils/0.24 mm2; Papillae are elongated; papillae reach into the top 1/3 of the epithelial layer; Basal cell hyperplasia; > 3 cells thick or >15% of epithelial thickness; Spongiosis (Photo courtesy of Michael Bonert / Wikimedia).

Potential Noninvasive Biomarker of EoE Disease Activity Identified

Researchers have identified a potential blood-based marker of disease activity for the severe and often painful food allergic disease eosinophilic esophagitis (EoE) – possibly leading to a blood test, which could spare EoE patients, often children, the discomfort and risk of the currently used invasive endoscopic monitoring procedures. More...
24 May 2016
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.