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Immunology

Image: A microscopic view of a typical neuroblastoma with rosette formation (Photo courtesy of Dr. Maria Tsokos, National Cancer Institute).

Neuropeptide May Serve as Biomarker for Neuroblastoma Patients

A study has found the common nerve protein Neuropeptide Y (NPY) to be elevated in the blood of those with an aggressive form of neuroblastoma, suggesting that NPY could serve as biomarker in a prognostic and/or treatment monitoring test, and as a new target for developing a more effective therapeutic drug for this early childhood cancer. More...
26 Oct 2016
Image: A transmission electron microscope (TEM) image of negative-stained, Fortaleza-strain Zika virus (red), isolated from a microcephaly case (Photo courtesy of the NIAID).

Biological Link Found between Zika Infection and Guillain-Barré Syndrome

Guillain-Barré is a very rare but potentially paralyzing disorder of the nervous system that appears days to weeks after infection with viruses or bacteria. More...
19 Oct 2016
Image: A diagram of the newly discovered mechanism of action of the bacterial superantigen toxins: Superantigens bind to both B7-2 and CD28, the major costimulatory receptors expressed on human immune cells. This binding enhances B7-2/CD28 receptor engagement, thereby inducing a powerful immune signal that evokes a harmful inflammatory storm (Photo courtesy of Professor Raymond Kaempfer).

Groundbreaking Immune Approach Targets Humans Instead of Bacteria

Staphylococcal and streptococcal infections affect millions of individuals each year and they are a leading cause of sepsis and account for many cases of pneumonia and post-surgical infections. More...
18 Oct 2016
Image: The Quantum Blue rapid test allow for the immediate measurement of fecal calprotectin (Photo courtesy of Bühlmann Laboratories).

Unnecessary Endoscopies Could Be Avoided with Fecal Blood Test

The majority of primary care patients referred for bowel endoscopy do not have significant colorectal disease (SCD), and are unnecessarily exposed to a small but realistic risk of severe endoscopy-associated complications. More...
14 Oct 2016
Image: Professor Bernhard Boehm and Dr Hou Han Wei holding their quick test kit for inflammation in diabetic patients (Photo courtesy of Nanyang Technological University).

Quick Test Detects Inflammation in Diabetic Patients

A new kit has been developed that will allow doctors to find out within minutes if diabetic patients are suffering from inflammation. Current procedures require patients to wait for several hours for the results obtained from the conventional full blood count test. More...
12 Oct 2016
Image: Immunohistochemical detection of human intestinal spirochetosis with signs of invasion (Photo courtesy of the US National Institute of Health).

Anti-Treponema Immunohistochemistry Cross-Reactivity Reported with Non-Treponema Spirochetes

Syphilis has different histopathologic presentations, and it can mimic a significant number of entities while human intestinal spirochetosis is characterized by the presence of a layer of spirochetes adherent to the apical epithelial surface of the colorectal mucosa. More...
12 Oct 2016
Image: The compact EUROBlotMaster processor for immunoblot strips (Photo courtesy of Euroimmun AG).

Increased Serum Cytokine Concentrations Reported in Guillain-Barré Syndrome

Guillain-Barré syndrome (GBS) is an acquired demyelinating peripheral neuropathy and it has been shown that macrophage activation contribute to the pathogenesis of GBS. Therefore macrophage-mediated factors could be the potential markers for disease diagnosis and status of GBS. More...
05 Oct 2016
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.