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Immunology

Image: The BD LSRII flow cytometer (Photo courtesy of Becton Dickinson).

Circulating Immune Cells Act As Idiopathic Pulmonary Fibrosis Biomarkers

Patients with fibrotic lung diseases, such as idiopathic pulmonary fibrosis (IPF), show progressive worsening of lung function with increased shortness of breath and dry cough. More...
14 Sep 2016
Image: Allergy degranulation processes: 1 - antigen; 2 - IgE antibody; 3 - FcεRI receptor; 4 - preformed mediators (histamine, proteases, chemokines, heparine); 5 - granules; 6 - mast cell; 7 - newly formed mediators (prostaglandins, leukotrienes, thromboxanes, PAF) (Image courtesy of Paweł Kuźniar / Wikimedia).

Guide Helps Physicians Diagnose and Manage Food Allergies

Based on recent evidence from guidelines, randomized controlled trials, and other research, a new review aims to provide physicians with a guide to help diagnose and manage food allergies in children and adults. It outlines common symptoms, causes, diagnosis, treatment, management, and immunization guidelines. More...
12 Sep 2016
Image: The BD FACSAria III fluorescent cell sorter (Photo courtesy of BD).

Lung Eosinophils Play Protective and Beneficial Role

During allergic reactions such as asthma, the immune system does not work correctly and responds in an abnormal way to harmless allergens present in the environment such as pollen and dust mites. More...
08 Sep 2016
Image: The Sgx Clarity System, being developed for highly sensitive next-generation immunodiagnostic detection, provides simple and intuitive operation (Photo courtesy of Singulex).

Certification Enables Development of New Technology in Next-Gen Immunodiagnostics

ISO (International Organization for Standardization) 13485:2012 Certification has been granted by NSAI to help ensure high standard development of a proprietary Single Molecule Counting (SMC) technology for clinical use as a next-generation immunodiagnostic platform. More...
06 Sep 2016
Image: A malignant melanoma on a patient’s skin (Photo courtesy of the National Cancer Institute).

Immune Analysis of Biopsies Predicts Response to Melanoma Immunotherapy

Immune response measured in tumor biopsies during the course of early treatment predicts which melanoma patients will benefit from specific immune checkpoint blockade drugs. More...
01 Sep 2016
Image: Immune molecule IL-1β (the \"hot spots\" shown) senses bacterial infections (Photo courtesy of the UC San Diego Health).

Innate Immune Sensor of Microbial Proteolysis Revealed

The human immune system can quickly recognize and respond to bacterial infections, but sometimes this reaction can become skewed, leading to autoimmune diseases such as rheumatoid arthritis. In this case, a person's own immune system attacks "self" proteins instead of just foreign invaders. More...
01 Sep 2016
Image: A histopathology of active toxoplasmosis of the myocardium. Numerous tachyzoites of Toxoplasma gondii are visible within a pseudocyst in a myocyte (Photo courtesy of Dr. Edwin P. Ewing, Jr.).

Latent Toxoplasmosis Prevalence Analyzed Retrospectively

Primary maternal infection with Toxoplasma gondii during pregnancy can lead to prenatal infection of the unborn child, and vertical diaplacental transmission of Toxoplasma can seriously damage the embryo. Some prenatally infected children, asymptomatic at birth, can develop retinochorioiditis and other sequelae months or years later. More...
01 Sep 2016
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.