Hematology
Hematological and Molecular Parameters Defined for CCUS and MDS
Patients with clonal cytopenia of undetermined significance (CCUS) have low blood counts and a normal bone marrow examination, but more advanced genetic testing shows the presence of a genetic mutation that is likely causing the low counts. More...11 May 2021
African-American MS Patients Experience More Rapid B-Cell Repopulation
Multiple sclerosis (MS) is a potentially disabling disease of the brain and spinal cord (central nervous system). In MS, the immune system attacks the protective sheath (myelin) that covers nerve fibers and causes communication problems between the brain and the rest of the body. More...06 May 2021
Cytokine Target Identified for Treatment-Resistant Hemophilia A
Hemophilia A, also called factor VIII (8) deficiency or classic hemophilia, is a genetic disorder caused by missing or defective factor VIII (FVIII), a clotting protein. Although it is passed down from parents to children, about 1/3 of cases found have no previous family history. More...04 May 2021
Synovial Fluid Neutrophils Phenotyped in Oligoarticular Juvenile Idiopathic Arthritis
Juvenile idiopathic arthritis (JIA) is an inflammatory rheumatic joint disease affecting children. Despite disease onset being at a young age, symptoms may be lifelong and include irreversible joint damage or growth disturbances. More...29 Apr 2021
Digital PCR Improves BCR-ABL1 Detection in Chronic Myeloid Leukemia
Specific targeting of the Bcr-Abl1 enzyme by tyrosine kinase inhibitors (TKI) revolutionized the management of chronic myeloid leukemia (CML) to the point that TKIs can offer near normal life expectancy for CML patients. More...22 Apr 2021
Tissue Counterpart to Monoclonal B-Cell Lymphocytosis Characterized
Monoclonal B-cell lymphocytosis (MBL) was initially proposed to recognize patients with a monotypic B cell population identified by peripheral blood (PB) flow cytometry (FC) that did not meet numerical criteria for chronic lymphocytic leukemia (CLL). More...21 Apr 2021
Coagulation Dysfunction and Infection Evaluated in Patients with AECOPD
Chronic obstructive pulmonary disease (COPD) is one of the common chronic airway obstructive diseases, characterized by persistent respiratory symptoms and airflow limitation. In acute exacerbation stage (AECOPD), patients developed respiratory failure often have circulatory and coagulation dysfunction, which was considered the cause of thrombosis events in the patients. More...14 Apr 2021
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In Other News
Genome Sequencing Identifies Myeloma Precursor Disease with Progression Risk
Flow-Cytometric Expression of Endoglin Assessed in B-Acute Lymphoblastic Leukemia
Lupus Genetic Risk Variant Allelic Enhancer Activity Discovered
Genome Sequencing More Informative than Cytogenetic Analysis in Myeloid Cancers
Genetic Mutations Identified for Rare VEXAS Syndrome
Paraproteins Identification Methods Compared for Monoclonal Gammopathies
Clonal Hematopoiesis and Recurrent Mutations Identified in Blood Cancers
COVID-19 Induces a Hyperactive Phenotype in Circulating Platelets
Hemoglobin Levels Measured with AI Microscope, Microfluidic Chips
Blood Tests Offer Early Indicator of Severe COVID-19
Rh Alloimmunization Explored in Chronically Transfused Thalassemia Patients
Next Generation Sequencing Finds More Gene Mutations for Leukemia
Biomarker Predicts Pancreatic Cancer Patients’ Response to CD40 Immunotherapy
Automated Leucocyte VCS Parameters Evaluated for Pathogenic Infections
TFP Inhibitor Levels Elevated in Bleeding Tendency Patients
RDW Levels Associated with Adverse Outcomes in COVID-19 Patients
ABO Histo-Blood Groups Influence Makeup of Gut Microbiome
Specific RUNX1 Mutations Cause Different Disease Types
Tryptophan Metabolism Is Dysregulated in Individuals with Fanconi Anemia
Coagulopathy Testing Linked to Better COVID-19 Outcomes
Preterm Infants Tolerate Restrictive Red Blood Cell Transfusion Strategy
Next Generation Sequencing Developed for Monitoring of Mixed Chimerism
Automated Hematologic Reference Intervals Defined for Newborns
The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.