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Molecular Diagnostics

Study Highlights Ethnic Diversity of Lupus-Linked Genes

A large genotyping study has identified multiple regions of the genome linked to the autoimmune disease systemic lupus erythematosus (SLE) in individuals of European, African, and Hispanic Amerindian ancestry. More...
03 Aug 2017
Image: A new large-scale genetic study provides a better understanding of Alzheimer\'s disease by uncovering two new risk genes (Photo courtesy of the American Academy of Neurology).

New Genes Found Raise Alzheimer’s Disease Risk

Two new genes that have been found that moves us closer to understanding the genetic underpinnings of Alzheimer's disease and raises the risk for the condition. More...
03 Aug 2017
Image: A scanning electron micrograph of a CD8+ T cell engaging a virus (Photo courtesy of Dennis Kunkel).

Genetic Variation Associated with Influenza Severity Identified

It is estimated that in the USA influenza -related deaths in recent years have ranged from 12,000 to 56,000. Factors like age, obesity, pregnancy and such chronic health conditions as asthma, chronic lung disease and heart disease are associated with an elevated risk of complications and death. More...
03 Aug 2017
Image: Co-first author Paul Northcott, Ph.D., an assistant member of the St. Jude Department of Developmental Neurobiology and author Xin Zhou, PhD, senior bioinformatics research scientist (Photo courtesy of Seth Dixon / St. Jude Children\'s Research Hospital).

Newly Driver Mutations Discovered for Medulloblastoma

An international consortium has completed a landmark genomics study of medulloblastoma, the most common pediatric brain tumor, revealing much information about subtypes and laying a foundation to expand precision medicine. The most comprehensive analysis yet of medulloblastoma identified genomic changes responsible for over 75% of the many tumors examined; as well as two new suspected cancer genes found exclusively in the least understood disease subgroups. More...
31 Jul 2017
Image: Digitally colorized transmission electron microscopic (TEM) image of Zika virus, which is a member of the family Flaviviridae. Virus particles, here colored red, are 40 nanometers in diameter, with an outer envelope, and an inner dense core (Photo courtesy of Cynthia Goldsmith, CDC).

Antibody-Based ELISA Detects Zika with High Specificity

A recently developed human monoclonal antibody-based assay is highly effective in detecting both recent and past Zika virus (ZIKV) infections and in discriminating Zika from other flavivirus infections. More...
31 Jul 2017
Image: A) Determination of the lesion for disc sampling; B) Application of the tape strip disc on the lesion; C) Even pressure applied for 20 seconds with the plunger; and D) Detaching the disc and transferred into a sterile vial for DNA isolation (Photo courtesy of the Pasteur Institute of Iran).

Novel Non-Invasive Sampling Technique Diagnoses Cutaneous Leishmaniasis

The definitive diagnosis of cutaneous leishmaniasis requires parasitological detection and it is usually based on direct detection of amastigotes in smears from lesions by microscopy and by the culturing of promastigotes from infected tissues. More...
27 Jul 2017
Image: The Magnetic Induction Cycler for real time polymerase chain reaction (Photo courtesy of Bio Molecular Systems).

RT-PCR Evaluated for Taenia Detection

Taenia solium, the pork tapeworm, and the cause of neurocysticercosis (NCC), has significant socioeconomic impacts on communities in developing countries. This disease, along with taeniasis is estimated to infect 2.5 to five million people globally. More...
27 Jul 2017
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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