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Molecular Diagnostics

Image: The Magnetic Induction Cycler for real time polymerase chain reaction (Photo courtesy of Bio Molecular Systems).

RT-PCR Evaluated for Taenia Detection

Taenia solium, the pork tapeworm, and the cause of neurocysticercosis (NCC), has significant socioeconomic impacts on communities in developing countries. This disease, along with taeniasis is estimated to infect 2.5 to five million people globally. More...
27 Jul 2017
Image: The gut contains trillions of microorganisms, but new research finds one bacterium that drives the growth of colorectal cancer cells (Photo courtesy of MNT).

Bacterium Actively Drives CRC Tumor Growth

Colorectal cancer (CRC) is a leading cause of cancer-related death. The recognition that microbial agents can contribute to the development of CRC raises hope for improving CRC diagnosis and treatment by incorporating both microbial and patient characteristics into clinical strategies. More...
27 Jul 2017
Image: A diagram of microRNA-mediated dynamic bidirectional shift between the subclasses of glioblastoma stem-like cells (Photo courtesy of Brigham and Women\'s Hospital).

Specific MicroRNA Identifies Glioblastoma Subtypes

Glioblastoma multiforme (GBM), an extremely aggressive brain cancer, is a very complex disease. It is characterized by a fast-growing tumor in the brain composed of many subpopulations of cells, including glioblastoma stem cells, which play a crucial role in glioblastoma initiation, expansion and therapy-resistance. More...
26 Jul 2017
Image: The Single Molecule Array (Simoa) HD-1 analyzer (Photo courtesy of Quanterix).

MicroRNA Technology Proves Useful for Liver Toxicity Detection

A single probe method has been developed for detecting microRNA from human serum using single molecule arrays, with sequence specificity down to a single base, and without the use of amplification by polymerases. More...
26 Jul 2017

Genomic Variants Contribute to Cognitive Impairment

Genetic alterations of rare deletions or duplications of small DNA segments, called copy number variants (CNVs), have been known to increase risk of neurodevelopmental disorders such as schizophrenia, autism spectrum disorder, and intellectual disability. More...
26 Jul 2017
Image: The Afirma Gene Expression Classifier kit for thyroid FNA Analysis reduces thyroid cancer surgery treatment costs (Photo courtesy of Veracyte).

Molecular Testing Evaluated for Thyroid Nodules

Thyroid nodules are a common clinical concern and increasing use of diagnostic imaging likely explains a large part of the increased incidence of thyroid nodules and the subsequent diagnosis of thyroid cancer that has been observed during the last three decades. More...
26 Jul 2017
Image: The enzyme E3 ubiquitin ligase (RFWD3) helps target other proteins on single-stranded DNA for degradation. B: Cells lacking RFWD3 show DNA repair defects (Photo courtesy of Julius-Maximilians-Universität).

New Gene Mutation Associated with Fanconi Anemia

Fanconi anemia is a rare genetic disease characterized by bone marrow failure heralded by low platelet counts and unusually large red blood cells. Mutations in over 20 genes have been identified as causative for Fanconi anemia, which encode proteins commonly involved in DNA repair mechanisms. More...
25 Jul 2017
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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