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Molecular Diagnostics

Image: Neurons were grown in tissue culture and stained with antibody to microtubule associated protein 2 (MAP2) protein in green and MAP tau in red. MAP2 is found only in dendrites and perikarya, while tau is found in these sites and in axons as well. DNA is shown in blue (Photo courtesy of EnCor Biotechnology Inc. via Wikimedia Commons)

Plasma-Based Algorithm Accurately Predicts Likelihood of Developing Alzheimer’s Disease

A team of Swedish researchers has created an algorithm for use by physicians lacking access to advanced diagnostic instruments, which accurately predicts future risk of developing Alzheimer’s disease (AD). More...
31 May 2021
Image: Schematic of workflow for urinary DNA jagged end analysis. Urinary DNA was subjected to an end-repair process; JI-U = jagged index–unmethylated (Photo courtesy of The Chinese University of Hong Kong)

Jagged Ends of Urinary Cell-Free DNA Assessed in Bladder Cancer Detection

Bladder cancer is where a growth of abnormal tissue, known as a tumor, develops in the bladder lining. In some cases, the tumor spreads into the bladder muscle. The most common symptom of bladder cancer is blood in the urine, which is usually painless. More...
27 May 2021
Image: Histopathology of Alzheimer\'s disease in the CA3 area of the hippocampus: Amyloid plaque (top right), neurofibrillary tangles (bottom left) and granulovacuolar degeneration (bottom center). All three images were taken at the same high magnification (Photo courtesy of Wikimedia Commons)

Early Warning Biomarker Proteins Appear Years or Decades Before Alzheimer’s Disease Symptoms

A large proteomic study linked abnormal blood levels of 38 proteins to higher risks of developing Alzheimer's disease within five years and showed that levels of 16 of these proteins could predict Alzheimer's disease risk two decades in advance. More...
26 May 2021
Image: The CHEMOSTAR Touch ECL & Fluorescence Imager (Photo courtesy of INTAS)

Non‐Invasive Urine Markers Differentiate Renal Cancer from Oncocytoma

Clear cell renal cell carcinoma, (ccRCC), is a type of kidney cancer. Clear cell renal cell carcinoma is also called conventional renal cell carcinoma. Clear cell renal cell carcinoma is named after how the tumor looks under the microscope. More...
25 May 2021
Image: The structure of human serum albumin (HSA) complexed with six palmitic acid molecules (Photo courtesy of Wikimedia Commons)

Measurement of Oxidized Serum Albumin for Diagnosis of Diabetic Kidney Disease

A recent paper reported that oxidized (cysteinylated) albumin in serum can be used as an early diagnostic marker for diabetic kidney disease. More...
25 May 2021
Image: Schematic of workflow for urinary DNA jagged end analysis. Urinary DNA was subjected to an end-repair process; JI-U = jagged index–unmethylated (Photo courtesy of The Chinese University of Hong Kong)

Jagged Ends of Urinary Cell-Free DNA Assessed in Bladder Cancer Detection

Bladder cancer is where a growth of abnormal tissue, known as a tumor, develops in the bladder lining. In some cases, the tumor spreads into the bladder muscle. The most common symptom of bladder cancer is blood in the urine, which is usually painless. More...
24 May 2021
Image: Dr. Tza-Huei Wang displays the PROMPT test cartridge for rapid diagnosis of gonorrhea infection (Photo courtesy of Johns Hopkins University)

Rapid, Automated Test Detects Gonorrhea and Determines Antibiotic Susceptibility

An inexpensive, portable diagnostic test that gives results in only 15 minutes is expected to revolutionize detection of sexually transmitted diseases such as gonorrhea. More...
24 May 2021
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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