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Molecular Diagnostics

Image: Curian immunofluorescent testing platform (Photo courtesy of Meridian Bioscience, Inc.)

Meridian Receives FDA Clearance for Rapid Fluorescent Immunoassay for Detection of Campylobacter Infection

Meridian Bioscience, Inc. (Cincinnati, OH, USA) has received U.S. Food and Drug Administration (FDA) clearance for its Curian Campy assay developed to be utilized on the Curian immunofluorescent testing platform. More...
14 Jan 2022
Image: QX200 AutoDG ddPCR System and QXDx BCR-ABL %IS Kit (Photo courtesy of Bio-Rad)

ddPCR Developed for BCR-ABL1 Fusion Transcript in B-Lymphoblastic Leukemia

Droplet digital polymerase chain reaction (ddPCR) is a novel polymerase chain reaction (PCR) technique reliant on massive sample partitioning to generate individual reaction chambers (droplets) in which individual amplification targets are detected. More...
12 Jan 2022
Image: The Promega MSI Analysis System V1.2 and the LMR-MSI systems are PCR-based methods for detecting microsatellite instability (MSI) in solid tumors (Photo courtesy of Promega)

Long Mononucleotide Repeat Markers Validated for Microsatellite Instability Detection

Mismatch repair deficiency (dMMR) predicts response to immune checkpoint inhibitor therapy in solid tumors. Long mononucleotide repeat (LMR) markers may improve the interpretation of microsatellite instability (MSI) assays. More...
12 Jan 2022
Image: ProGastro SSCS is a multiplex real time PCR for the detection and differentiation of Salmonella, Shigella, Campylobacter, (C. jejuni and C. coli only, undifferentiated) nucleic acids and Shiga Toxin 1 (stx1) and Shiga Toxin 2 (stx2) genes (Photo courtesy of Hologic)

Commercial RT-PCR Tests Compared to Culture for Bacterial Gastroenteritis

Nucleic acid-based testing (culture-independent diagnostic testing, CIDT) for bacterial gastroenteritis offers three major advantages over culture-based diagnosis: it has better analytical sensitivity, is less labor intensive through automation, and has faster turnaround times. More...
11 Jan 2022
Image: Human prostate specific antigen (PSA) with bound substrate from complex with antibody (Photo courtesy of Wikimedia Commons)

A Novel Lateral Flow Immunoassay System for Determination of Prostate Specific Antigen

A recent paper described the development of a highly portable quantitative screening test for prostate cancer. More...
10 Jan 2022
Image: Microscope image of the cells used to test nanoparticles (Photo courtesy of Jordan Green; Johns Hopkins Medicine)

New Color-Coded Test Quickly Reveals If Medical Nanoparticles Deliver Their Payload into Target Cells

A color-coded test for new nanoparticles can quickly identify which formulations will effectively deliver the medicines they carry. More...
07 Jan 2022
Image: A) NDUFS1 immunohistochemistry staining of prostate cancer (PCa) tissue microarray (TMA) samples and B) ATP5O immunohistochemistry staining of PCa TMA samples. Staining intensity as per number. Scale bar = 100 µm (Photo courtesy of Medical University of Vienna)

Novel Protein Biomarkers Identified for Prostate Cancer Aggressiveness

Prostate cancer is the most commonly diagnosed cancer in men and is among the top five causes of cancer-related death. In most cases, prostate cancer can be successfully treated but there is a group of patients who suffer an aggressive course and often fatal outcome. More...
05 Jan 2022
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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