Molecular Diagnostics

Image: The Chemagic 360 extracts DNA and uses transiently magnetized rods to attract the beads after binding to the nucleic acids (Photo courtesy of PerkinElmer).

Blood Group Locus Contributes to COVID-19 Severity Risk

There is considerable variation in disease behavior among patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19). More...
02 Jul 2020

Image: Variability in prostate cancer–specific multigene panels; genetic testing registry as of August 2019 (Photo courtesy of Saud H. AlDubayan, MD).

Precision Medicine-Based Genetic Testing Developed for Prostate Cancer

Germline testing (GT) is a central feature of prostate cancer (PCA) treatment, management, and hereditary cancer assessment. Critical needs include optimized multigene testing strategies that incorporate evolving genetic data, consistency in GT indications and management, and alternate genetic evaluation models that address the rising demand for genetic services. More...
01 Jul 2020

DIASOURCE (A Biovendor Company)

Image: This image depicts a DNA molecule that is methylated on both strands on the center cytosine. The two white spheres represent methyl groups (Photo courtesy of Wikimedia Commons)

Sensitive and Accurate Cancer Detection Through Analysis of Circulating Free DNA Methylation Patterns

An advanced liquid biopsy method for the detection and diagnosis of various types of cancer is based on the analysis of circulating tumor DNA methylation profiles. More...
30 Jun 2020

$Image: Circulating tumor DNA (ctDNA) is found in serum and plasma fractions from blood. The mechanism of ctDNA release is unknown, though apoptosis, necrosis, and active secretion from tumor cells have been hypothesized. Once ctDNA is isolated, it can be sequenced for mutational analysis (Photo courtesy of Wikimedia Commons)$

Highly Sensitive Liquid Biopsy Technique Brings Personalized Cancer Monitoring a Step Closer

A modified liquid biopsy method enables detection of circulating tumor DNA (ctDNA) with much greater sensitivity than previously used techniques and demonstrates the potential to revolutionize all aspects of cancer care, from early detection to personalized treatment and monitoring. More...
29 Jun 2020

Image: The MiSeq Next Generation Sequencer is an integrated instrument that performs clonal amplification, genomic DNA sequencing, and data analysis with base calling, alignment, variant calling, and reporting in a single run (Photo courtesy of Illumina).

Gut Microbiome Dysbiosis Characterized in Parkinson’s Disease

Parkinson’s disease (PD) is a common, progressive, and debilitating disease, which currently cannot be prevented or cured. With the exception of rare genetic forms, the cause of PD is unknown. Symptoms start gradually, sometimes starting with a barely noticeable tremor in just one hand. Tremors are common, but the disorder also commonly causes stiffness or slowing of movement. More...
29 Jun 2020

Image: The NanoDrop 2000 and 2000c are full-spectrum, UV-Vis spectrophotometers used to quantify and assess purity of DNA, RNA, Protein and more (Photo courtesy of Thermo Fisher Scientific).

Serum Mir‐22 Prognostic Marker Explored for Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is an aggressive hematopoietic stem cell malignancy that is characterized by the clonal proliferation of myeloid precursors. Abnormal accumulation of leukemic blasts in the bone marrow, blood, and other tissues results in significant reductions of normal blood cells. More...
25 Jun 2020

Image: Corbett Rotor-Gene 6000 Real Time PCR Machine (Photo courtesy of Corbett Life Science).

Isothermal Amplification Method Used to Detect Salmonella Subtypes

Salmonella is a common cause of foodborne disease worldwide, including Australia. More than 85% of outbreaks of human salmonellosis in Australia were caused by five Salmonella serovars. Rapid, accurate, and sensitive identification of Salmonella serovars is vital for diagnosis and public health surveillance. More...
25 Jun 2020

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Veterinary Hematology Analyzer

Exigo H400

3-Part Differential Hematology Analyzer
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NATtrol Chlamydia trachomatis Positive Control

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Autoimmune Disease Diagnostic

Chorus ds-DNA-G

In Other News

Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.