Molecular Diagnostics
Genetic Background and Clinicopathologic Features Established for Adult-Onset Nephronophthisis
Nephronophthisis (NPH) is a genetic disorder of the kidneys which mainly affects children. It is classified as a medullary cystic kidney disease. The disorder is inherited in an autosomal recessive fashion and, although rare, is the most common genetic cause of childhood kidney failure. More...06 May 2021
LAMP Assay Developed to Diagnose High HBV DNA Levels
Worldwide, 257 million people are chronically infected with hepatitis B virus (HBV) and 887,000 annually die from cirrhosis or liver cancer. Since more than 95% of HBV-infected people live in low-income and middle-income countries (LMICs) and only 12-25% of infected people are eligible for anti-HBV therapy. More...05 May 2021
Protein Biomarker Increases Sensitivity of a Urine-based Prostate Cancer Test
A team of British researchers increased the sensitivity of an advanced RNA and DNA biomarker-based urine test for diagnosis of aggressive prostate cancer by including the measurement of a protein biomarker, which is expected to reduce the number of unnecessary biopsies performed every year by up to 35%. More...05 May 2021
GPS Assay Associated with Long-Term Prostate Cancer Outcomes
Long-term cancer outcomes are an important consideration when deciding between active surveillance (AS) and immediate treatment for newly diagnosed prostate cancer. Multiple prospective AS studies that predominantly include patients at the lowest risk of progression have demonstrated a low risk of distant metastasis (DM) and prostate cancer–specific mortality (PCSM) with extended follow-up. More...03 May 2021
A Rapid Metabolomic Test for Early Diagnosis of Myocardial Infarction
A metabolomic platform with GC/MS (gas chromatography–mass spectrometry) and LC/MS (liquid chromatography–mass spectrometry) instrumentation has been developed to profile plasma metabolites of patients with chest pain for early detection of myocardial infarction (MI). More...03 May 2021
Genetic Factors Linked to Severe COVID-19, Viral Infections in Children
Although children, in general, are thought to experience relatively mild infections with SARS-CoV-2, a subset of infected children do become very ill and develop a condition known as Multisystem Inflammatory Syndrome in Children (MIS-C). More...29 Apr 2021
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In Other News
New Genetic Factors Involved in Sudden Unexpected Death in Children
Novel Urine-based Liquid Biopsy for Early Detection of Aggressive Prostate Cancer
Serum Amyloid A Levels Linked to Likelihood of Developing Severe COVID-19
Different Methods Compared for Isolating Fungal DNA
Digital PCR Improves BCR-ABL1 Detection in Chronic Myeloid Leukemia
RNA-Sequencing Predicts Immunotherapy Success in Bladder Cancer
An Ultrasensitive Assay for Measurement of Levels of Cathepsin B in the Blood
A Method for Accurately Assessing the Latent Virus Reservoir in Chronic HIV Patients
Sensitive PCR Test Detects Early Stage Lyme Disease
Randox Discovery Diagnostic Analyzer Wins 2021 Red Dot Award for High Design Quality
T Cells Recognize Recent SARS-CoV-2 Variants
Novel Lipid Biomarker Detects Senescent Cells
Leukocyte Epigenomics and Artificial Intelligence Predict Late-Onset Alzheimer’s Disease
A Protein Biomarker Aids Cancer Patients by Controlling the Dosage of Highly Toxic Cisplatin
Genome Sequencing Identifies Myeloma Precursor Disease with Progression Risk
Single-Cell Transcriptomic Analysis Traces Neuroblastomas to Developing Adrenal Neuroblasts
Advances in High-Tech Methods for Cervical Cancer Screening
Salivary Diagnostic Signatures of Concussion Found in Male Athletes
A Mass Spectrometry Approach for Monitoring Progress of Multiple Myeloma
Whole-Genome Sequencing Aids Rare Disease Diagnosis
Lupus Genetic Risk Variant Allelic Enhancer Activity Discovered
PCR Method Identifies Microsatellite Instability in Tumor-Derived Samples
Disease Diagnosis Based on Infrared Analysis of Blood Samples
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
