Molecular Diagnostics
![Image: Two-dimensional structure of lactosylceramide (Lac-Cer). Lac-Cer levels in the circulation could have prognostic value for SLE patients with CVD (Photo courtesy of [U.S] National Library of Medicine)](https://globetechcdn.com/mobile_labmedica/images/stories/articles/article_images/2021-08-23/GMS-067B.jpg "Image: Two-dimensional structure of lactosylceramide (Lac-Cer). Lac-Cer levels in the circulation could have prognostic value for SLE patients with CVD (Photo courtesy of [U.S] National Library of Medicine)")
Sphingolipids Are Prognostic Biomarkers for African American SLE Patients with Cardiovascular Disease
A recent study found that lactosylceramide levels may have a “predictive” value and sphingolipidomics have an added benefit to currently available tools for the early diagnosis and prognosis of African American systemic lupus erythematosus (SLE) patients with cardiovascular disease (CVD). More...23 Aug 2021
CSF biomarkers Compared for Down Syndrome and Inherited Alzheimer’s
Although most people with Down’s syndrome will experience brain changes as they age, not everyone will develop Alzheimer’s disease or another type of dementia. Whilst having Down’s syndrome does put a person at increased risk, estimated at 1 in 3 people in their 50s, and closer to 2 in 3 aged over 60, it is not inevitable for all. More...19 Aug 2021
![Image: Gross pathology of idiopathic cardiomyopathy. Opened left ventricle of heart shows a thickened, dilated left ventricle with subendocardial fibrosis manifested as increased whiteness of endocardium (Photo courtesy of [U.S.] Centers for Disease Control and Prevention)](https://globetechcdn.com/mobile_labmedica/images/stories/articles/article_images/2021-08-17/GMS065.jpg "Image: Gross pathology of idiopathic cardiomyopathy. Opened left ventricle of heart shows a thickened, dilated left ventricle with subendocardial fibrosis manifested as increased whiteness of endocardium (Photo courtesy of [U.S.] Centers for Disease Control and Prevention)")
A Circulating Adipokine Is a Possible Biomarker for Severity of Systemic Sclerosis-Associated Interstitial Lung Disease
A circulating adipokine (a cytokine chemical messenger produced by adipose tissue) has been identified as a possible biomarker associated with the severity of systemic sclerosis-associated interstitial lung disease. More...15 Aug 2021
Lipid Metabolism Affects GBA-Associated Parkinson's Disease
Parkinson’s disease (PD) is the most common neurodegenerative disorder after Alzheimer’s disease. The pathognomonic hallmark of PD is the degeneration of dopaminergic neurons of the substantia nigra and, consequently, the striatal dopamine depletion. More...13 Aug 2021
Genomes of Advanced Neuroendocrine Neoplasms Unveil Subtypes
Metastatic and locally-advanced neuroendocrine neoplasms (aNEN) form clinically and genetically heterogeneous malignancies, characterized by distinct prognoses based upon primary tumor localization, functionality, grade, proliferation index and diverse outcomes to treatment. More...13 Aug 2021
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.