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Molecular Diagnostics

Image: Blood-based assay could aid management of relapsing-remitting form of MS (Photo courtesy of Quanterix)

NfL Blood Test to Aid Prognosis and Treatment of Multiple Sclerosis

A blood-based assay has the potential to serve the multiple sclerosis (MS) community in management of relapsing-remitting form of the disease. More...
25 Apr 2022
Image: The CRC-PREVENT study will evaluate individuals at risk for colorectal cancer (Photo courtesy of Geneoscopy)

RNA-Based Noninvasive Gut Tests Enable Early Colorectal Cancer Screening

A new diagnostic platform uses stool-derived eukaryotic RNA (seRNA) to detect colorectal cancer and precancerous adenomas. Unlike other noninvasive screening options that use DNA or blood-based biomarkers, the proprietary method from Geneoscopy Inc. (St. Louis, MO, USA) analyzes RNA extracted from patient stool samples to provide the phenotypic and quantitative information necessary to accurately detect precancerous lesions. More...
25 Apr 2022
Image: Researchers have identified a blood plasma biomarker for early-stage AD (Photo courtesy of Pexels)

Blood Plasma Biomarker May Facilitate Rapid Diagnosis of Early-Stage Alzheimer’s Disease

The discovery of a unique ratio of metabolites from blood samples of early-stage Alzheimer’s disease patients promises to speed diagnosis, allowing earlier treatments to be initiated. More...
22 Apr 2022
Image: BD Rhapsody TCR/BCR multiomic assay advances immunology research capabilities in multiomics (Photo courtesy of BD)

New BD Assay Speeds Discovery in Autoimmune Disorders, Immuno-Oncology, and Infectious Diseases

Becton, Dickinson and Company (BD Franklin Lakes, NJ, USA) has launched the BD Rhapsody TCR/BCR Multiomic Assay, an innovative set of reagents that enables researchers to more easily and comprehensively analyze important cells in the immune system, providing a tool to advance research in autoimmune disorders, immuno-oncology and infectious diseases. More...
22 Apr 2022
Image: A new study has affirmed a useful blood biomarker for group of brain disorders (Photo courtesy of Mayo Clinic)

Testing for Protein in Blood Receives More Support as Biomarker for Brain Disorders

Frontotemporal dementia (FTD) is a group of brain disorders characterized by changes in behavior, cognition, language or movement that has few treatment options. These disorders involve degeneration and shrinkage of the frontal and temporal lobes of the brain. Now, a test of protein in the blood has received further support as a biomarker for patients diagnosed with FTD. More...
21 Apr 2022
Image: A blood test could help diagnose skin cancer (Photo courtesy of Pexels)

Blood Test to Diagnose Skin Cancer May Help Avoid Invasive Skin Biopsies

Recent advances in liquid biopsy have proposed less-invasive alternatives for cancer diagnosis and monitoring using minimal invasion at sample collection, and circulating tumor cells (CTCs) have been considered a promising blood-based surrogate marker of primary tumors. Now, new research indicates that testing an individual’s blood can reveal the presence of CTCs. Such tests may allow patients to forego invasive skin biopsies to determine whether they have skin cancer. More...
21 Apr 2022
Image: The LUNA-FL Dual Fluorescence Cell Counter (Photo courtesy of Logos Biosystems)

Tumor Suppressor Adenomatous Polyposis Coli Regulates T Lymphocyte Migration

Familial adenomatous polyposis (FAP) is an autosomal dominant inherited disease that often results from germline mutations in the adenomatous polyposis coli (APC) gene, a tumor suppressor and polarity regulator. APC protein regulates the Wnt/β-catenin signaling pathway as a component of the β-catenin destruction complex. More...
20 Apr 2022
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.