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Molecular Diagnostics

Image: DNA droplets play an essential role in cellular functions (Photo courtesy of Tokyo University of Technology)

Novel Method Uses DNA Droplets for Early Disease Detection

By combining the technologies of DNA droplets and DNA computing, scientists have developed computational DNA droplets which can recognize specific patterns in tumor biomarker microRNA sequences. More...
06 Jun 2022
Image: DNA shed from colon cancers into bloodstream can guide chemotherapy (Photo courtesy of Unsplash)

Testing for DNA Shed from Colon Cancers into Bloodstream Guides Chemotherapy After Surgery

A new research study has shown that circulating tumor DNA (ctDNA) - genetic material shed from tumors into the bloodstream - can identify colon cancer patients who can most benefit from chemotherapy following surgery and spare other patients the need for this form of treatment. More...
06 Jun 2022
Image: New blood test can help doctors diagnose tuberculosis and monitor treatment (Photo courtesy of Pexels)

Blood Test May Be a Game-Changer for TB Diagnoses and Treatment

A new highly sensitive blood test for tuberculosis (TB) screens for DNA fragments of the Mycobacterium tuberculosis bacteria that causes the deadly disease. More...
03 Jun 2022
Image: Blood test to aid detection and evaluation of diseases associated with NETosis (Photo courtesy of Pexels)

Blood Test Detects and Monitors Cell Death to Predict Disease Severity

Using routine blood tests, a simple, low cost, accessible technology can detect NETosis which is a unique form of cell death, predict disease severity, and monitor its progression and response to treatment. More...
03 Jun 2022
Image: New article reviews efficacy of current non-invasive methods for assessing non-alcoholic fatty liver disease (Photo courtesy of Pexels)

Non-Invasive Tests for Diagnosing Liver Diseases Could Shape Future Clinical Care

Recent studies have focused on exploring non-invasive tests for NAFLD, NASH, and fibrosis, for clinical applications. Now, researchers have collated recent developments in NAFLD assessment and analyzed the benefits and limitations of the new methods in a review made available online. More...
03 Jun 2022
Image: Abnormal accumulation of tau protein in neuronal cell bodies (arrow) and neuronal extensions (arrowhead) in the neocortex of a patient who had died with Alzheimer`s disease (Photo courtesy of Wikimedia Commons)

Results of Alzheimer’s Disease Blood Tests Are Skewed by Unrelated Chronic Conditions

The affect of chronic medical conditions such as chronic kidney disease on circulating levels of phosphorylated tau proteins (p-tau) must be evaluated before a p-tau blood test can be used for diagnosis of Alzheimer’s disease and other forms of dementia. More...
02 Jun 2022
Image: Various kinds of extracellular vesicles (EVs) (Photo courtesy of American Physiological Society)

Liquid Biopsy Predicts Success of ICI Treatment in Lung Cancer Patients

Compared to an invasive tumor biopsy procedure, an extracellular vesicle-based liquid biopsy method was shown to better predict treatment response and survival in patients with non-small cell lung cancer who were undergoing treatment with immune-checkpoint inhibitors (ICIs). More...
02 Jun 2022
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