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Molecular Diagnostics

Abnormal accumulation of tau protein in neuronal cell bodies (arrow) and neuronal extensions (arrowhead) in the neocortex of a patient who had died with Alzheimer\'s disease. (Credit: Wikimedia Commons)

A Phosphorylated Tau Protein Is Diagnostic for Early Stage Alzheimer’s Disease in Down Syndrome Patients

A blood test that determines circulating levels of the Alzheimer's disease (AD) biomarker protein phospho-tau217 (p-tau217) was found to distinguish AD from other neurodegenerative diseases in persons with Down syndrome. More...
01 Sep 2022
Image: In vivo tracheobronchial biopsy from patient with COVID-19-associated pulmonary aspergillosis (CAPA) and invasive Aspergillus tracheobronchitis (Photo courtesy of The Lancet Respiratory Medicine).

Mechanism Behind Deadly Fungal Infection with Influenza or Covid-19 Deciphered

Every year, hundreds of thousands of people worldwide end up in intensive care with influenza or Covid-19. About 15% of them develop an additional lung infection with the common fungus Aspergillus (aspergillosis). More...
31 Aug 2022
Image: Micrograph of triple-negative breast cancer cells (Credit: Baylor Medical College)

Gene Deletion Underlies Resistance to Chemotherapy in Triple-Negative Breast Cancer

A proteognomics approach was used to identify biomarkers in samples from triple negative breast cancer (TNBC) patients that were associated with resistance to chemotherapy treatment. More...
29 Aug 2022
Image: Histology of anaplastic thyroid carcinoma that features cellular pleomorphism, large atypical cells, myxoid degeneration, and bizarre giant cells (Photo courtesy of Cesar A. Moran, MD).

Mutation Testing Utilized in Anaplastic Thyroid Cancer

Mutations in two key oncogenes are associated with patient outcomes in anaplastic thyroid carcinoma (ATC), pointing to the utility of tumor mutation testing during treatment decision making for individuals with the disease. More...
26 Aug 2022
Image: Results from STORK prenatal genetic test, shown in foreground (Photo courtesy of Columbia University Irving Medical Center).

Prenatal Test Reduces Time of Detecting Chromosomal Abnormalities

A newly developed prenatal test can determine if a fetus or embryo has the right number of chromosomes at a fraction of the time and cost of currently available clinical genetic tests.

 More...
24 Aug 2022
Image: The new multiplex QIAstat-Dx Viral Vesicular Panel is designed to support research and surveillance efforts (Photo courtesy of QIAGEN)

First Syndromic Test Differentiates Between Monkeypox and Five Pathogens with Similar Symptoms

The first-ever syndromic test differentiates between monkeypox and five other pathogens which cause similar symptoms and produce similar-looking vesicular lesions. More...
18 Aug 2022
Image: A DNA test that identifies Lyme disease in horses could have applications for humans (Photo courtesy of Unsplash)

DNA Test for Lyme Disease in Horses Could Diagnose Difficult-to-Detect Illnesses in Humans

Scientists aiming to help heal a sick horse have created an ultra-sensitive DNA test that could have applications for difficult-to-detect illnesses in humans such as Lyme disease. More...
18 Aug 2022
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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