Molecular Diagnostics
Nanopore Sequencing Detect Pathogens in Knee Periprosthetic Joint Infection
The number of total knee arthroplasty (TKA) is currently increasing substantially, and it is expected to increase more than two times in the next decade worldwide. With the increasing number of TKA, the number of prosthetic joint infections (PJIs) is also increasing, and PJI is currently regarded as the most common etiology for revision TKA. More...05 Jan 2023
Multi-Cancer Detection Blood Test to Enable Early Diagnosis and Treatment
The US Food and Drug Administration (FDA) has granted Breakthrough Device Designation to a Multi-Cancer Detection Blood Test (MCDBT) that is intended for early detection of multiple cancer types (esophageal, liver, lung, ovarian, and pancreatic cancers) in adults of either sex, aged 50-75 years old, at average risk for cancer. More...04 Jan 2023
Blood-Based Screening Test for Colorectal Cancer Demonstrates Strong Clinical Performance
A blood test for the detection of colorectal cancer (CRC) has demonstrated 83% sensitivity with specificity of 90%, paving the way for the first potential US FDA-approved blood test for CRC screening. More...03 Jan 2023
Blood Test Helps Diagnose Inaccessible Brain Tumors
Presently, no blood test is available for diagnosing brain cancers, and doctors have to rely on complex surgical procedures to obtain tumor tissue for histopathological evaluation. Now, a new blood test can detect the cells released from the brain tumor that are extremely rare and hard to detect, enabling early diagnosis and treatment. More...03 Jan 2023
Clinical Microarray System Developed for Genetic Analysis Screening
In precision medicine, preoperative or postoperative genetic testing can be used to stratify patients according to disease states and select appropriate drugs, enabling efficient delivery of personalized treatment. More...02 Jan 2023
First Leukemia Diagnostic Test Based on DNA Sequencing Detects up To 51 Gene Mutations
Until 2022 the only leukemia tests done could detect two gene mutations. Now, a new leukemia diagnostic test is capable of detecting 51 gene mutations, marking a significant technological and medical advancement. More...02 Jan 2023
Biomarker Test Detects Alzheimer’s Neurodegeneration in Blood
Scientists have applied their knowledge of molecular biology and biochemistry of tau proteins in different tissues, such as the brain, to develop a technique to selectively detect “brain-derived tau,” or BD-tau, a novel marker of Alzheimer’s disease neurodegeneration, while avoiding free-floating “big tau” proteins produced by cells outside the brain. More...28 Dec 2022
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