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Molecular Diagnostics

Image: Non-invasive malaria screening device uses light for diagnosis (Photo courtesy of Pexels)

Rapid Diagnostic Test Uses Light to Detect Malaria without Blood Samples

Current rapid malaria tests involve applying a blood sample to a testing strip that can detect the presence of malaria-causing plasmodium parasites in red blood cells. Now, scientists have developed a hand-held screening device that can scan a patient’s arm or finger to detect the presence of malaria, eliminating the need to draw blood. More...
09 Jan 2023
Image: Placenta accreta spectrum is a life-threatening complication that poses a threat to both mother and baby (Photo courtesy of Pexels)

First Blood Panel to Detect Deadly Placenta Accreta Spectrum

Placenta accreta spectrum (PAS) is a major life-threatening pregnancy complication for both the mother and the baby. Now, a new study aims to create a targeted test for predicting PAS during pregnancy, thus better preparing patients and practitioners for the delivery day. More...
09 Jan 2023
Image: Researchers have discovered diagnostic potential of amniotic fluid cells RNA-sequencing in deciphering rare diseases (Photo courtesy of Pexels)

Amniotic Fluid Cells RNA-Sequencing Demonstrates Diagnostic Potential in Deciphering Rare Diseases

Researchers have discovered that applying amniotic fluid cells obtained during 16-24 weeks of pregnancy as a novel sample type for RNA-sequencing in prenatal diagnosis of rare diseases could help more families with tailored clinical management. It is the first proof-of-concept study to demonstrate the potential clinical utility of amniotic fluid cells RNA-sequencing. More...
05 Jan 2023
Image: Simple nasal swab can provide early warning of emerging viruses (Photo courtesy of Pexels)

Single Immune System Molecule on Nasal Swabs Detects Stealthy Viruses Not Identified in Standard Tests

Researchers have found that testing for the presence of a single immune system molecule on nasal swabs can help detect stealthy viruses not identified in standard tests. More...
05 Jan 2023
Image: A Cas12a2 protein unzips a DNA double helix, allowing it to cut the single strands of DNA (Photo courtesy of University of Texas at Austin)

CRISPR Protein Could Yield New Tests for Many Viruses

In a first for the genetic toolset known as CRISPR, a recently discovered protein has been found to act as a kind of multipurpose self-destruct system for bacteria, capable of degrading single-stranded RNA, single-stranded DNA and double-stranded DNA. With its abilities to target so many types of genetic material, the discovery holds potential for the development of new inexpensive and highly sensitive at-home diagnostic tests for a wide range of infectious diseases. More...
05 Jan 2023
Image: The MicroScan autoSCAN-4 semi-automated system provides simplified ID/AST testing in a highly reliable and affordable package and confirmed the results of the study (Photo courtesy of Beckman Coulter)

Nanopore Sequencing Detect Pathogens in Knee Periprosthetic Joint Infection

The number of total knee arthroplasty (TKA) is currently increasing substantially, and it is expected to increase more than two times in the next decade worldwide. With the increasing number of TKA, the number of prosthetic joint infections (PJIs) is also increasing, and PJI is currently regarded as the most common etiology for revision TKA. More...
05 Jan 2023
Image: The OverC MCDBT has been granted Breakthrough Device Designation by the US FDA (Photo courtesy of Burning Rock)

Multi-Cancer Detection Blood Test to Enable Early Diagnosis and Treatment

The US Food and Drug Administration (FDA) has granted Breakthrough Device Designation to a Multi-Cancer Detection Blood Test (MCDBT) that is intended for early detection of multiple cancer types (esophageal, liver, lung, ovarian, and pancreatic cancers) in adults of either sex, aged 50-75 years old, at average risk for cancer. More...
04 Jan 2023
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