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Molecular Diagnostics

Next-Generation Sequencing of Targeted Capture Genes a Sensitive Method for Diagnosis of Inherited Eye Disorders

A recent study showed that a targeted enrichment and next-generation sequencing method for genetic diagnostic testing of patients with inherited eye disorders was more accurate and sensitive than an approach based on exome sequencing, which focuses on the DNA in the 1% of the human genome that code for proteins.  More...
30 Nov 2014
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DNA Sequencing Identifies Mitochondrial Mutations in Glaucoma Patients

Diagnosis of glaucoma may be simplified by the development of a gene sequencing technique that detects mutations in the mitochondrial DNA of glaucoma patients.   More...
26 Nov 2014
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Human Genome Mapping Gaps Found by Latest Technology

Thousands of never-before-seen genetic variants in the human genome have been uncovered using a new genome sequencing technology and these discoveries close many human genome mapping gaps that have long resisted sequencing.  More...
26 Nov 2014
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Molecular Test Identifies Acute Transplant Rejection

The development of noninvasive molecular assays to improve disease diagnosis and patient monitoring is a critical need in renal transplantation, as acute rejection increases the risk for chronic graft injury and failure.  More...
25 Nov 2014
Image: Histopathology of ovarian serous papillary borderline tumor, intracystic, without surface cortical involvement (Photo courtesy of Brown University).

Prognostic Biomarker Candidates Identified for Ovarian Cancer

Two independent classes of novel candidate prognostic markers for ovarian cancer have been identified advancing efforts to develop targeted therapies for the disease.  More...
25 Nov 2014

Kidney Transplant Patients Identified at High Risk of Rejection

A quantitative real-time PCR-based assay can identify kidney transplant patients who are at high risk of acute rejection.  More...
18 Nov 2014
Histopathology of colonic adenocarcinoma; the glands are enlarged and filled with necrotic debris (Photo courtesy of the University of Utah).

Promising Blood Biomarkers Isolated for Colorectal Cancer

The search for blood-borne biomarkers that could be used to screen for colorectal cancer has uncovered two promising candidates that may one day lead to the development of a simple blood test.  More...
12 Nov 2014
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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