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Molecular Diagnostics

Image: The Xpert Ebola Assay cartridge (Photo courtesy of Cepheid Inc.).

Rapid Diagnostic Assay for Ebola Field Tested

Rapid diagnostic methods are essential in control of Ebola outbreaks and lead to timely isolation of cases and improved epidemiologic surveillance, but diagnosis during Ebola outbreaks in West Africa has relied on PCRs performed in laboratories outside the region.   More...
02 Feb 2016
Image: Molecular surface of the capsid of human rhinovirus, one of the viruses which cause acute respiratory infections (Photo courtesy of A. J. Cann).

Blood Test Could Identify Which Patients Need Antibiotics

Acute respiratory infections caused by bacterial or viral pathogens are among the most common reasons for seeking medical car and despite improvements in pathogen-based diagnostics, most patients receive inappropriate antibiotics.  More...
31 Jan 2016
Image: Human papillomavirus (HPV)-positive head and neck squamous cell carcinoma (HNSCC) identified by in situ hybridization (Photo courtesy of Jennifer L. Hunt, MD, and Wikimedia).

Oral HPVs Associated with Risk of Incident Head and Neck Cancers

A prospective study suggests that detection in the oral cavity of certain human papillomavirus types is associated with higher risk of incident head and neck squamous cell carcinoma, suggesting that the role of HPV in HNSCC may be even more important than currently recognized.  More...
31 Jan 2016
Image: T1 weighted sagittal cervical spine MRI showing degenerative disc disease, osteophytes, and osteoarthritis of C5-C6 (Image courtesy of Wikimedia).

New Approach to Aid in Diagnosing Lower Back Pain Revealed

In a clinical study, scientists have identified a potential new method, based on biochemical profiling of serum for circulating cytokines, that may assist in refining personalized diagnoses of disc diseases and possibly even in distinguishing between severe and mild conditions.   More...
27 Jan 2016
Image: Bone marrow aspirate of acute myeloid leukemia: Azurophilic granularity can be seen in essentially all of the blasts and variability in nuclear size and contour is observable (Photo courtesy of Dr. John Lazarchick, MD).

Early and Accurate Prediction of Leukemia Made Possible

Acute myeloid leukemia is the most common type of leukemia in adults and recent studies demonstrate that early and accurate prediction of this aggressive cancer is possible how it will develop in individuals.  More...
25 Jan 2016
Image: The IVIS Lumina Series III Preclinical in vivo Imaging System (Photo courtesy of Perkin Elmer).

Key Genes Identified for Leukemia Development

Human leukemia is characterized by the prevalence of recurrent chromosomal translocations, resulting in the generation of chimeric fusion proteins with aberrant oncogenic activities.   More...
25 Jan 2016
Image: Clinical features of local recurrences that are defined as the reappearance of melanoma in or contiguous with an excision scar or graft and bearing an in situ component (Photo courtesy of Dr. Paola Savoia).

Blood Test Monitors DNA Fragments for Melanoma Metastases

A blood test which monitors blood levels of DNA fragments from dead cancer cells does a superior job than the current standard test at tracking the severity and potential spread of metastatic melanoma.  More...
25 Jan 2016
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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